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January 1978

Portacaval Shunt and Hyperlipidemia

Author Affiliations

From the Departments of Surgery, Denver Veterans Administration Hospital and University of Colorado Medical Center, Denver.

Arch Surg. 1978;113(1):71-74. doi:10.1001/archsurg.1978.01370130073012

• The use of a completely diverting portacaval shunt for the purpose of lowering the serum concentration of cholesterol and low-density lipoproteins is reviewed and a recommendation provided that such a shunt for hyperlipidemia should be considered for type II individuals.

(Arch Surg 113:71-74, 1978)

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Russell D, Heimann KW, Levin SE, et al:  Portacaval shunt for homozygous hypercholesterolaemia . Lancet 2:1205, 1976.Article
Cywes S, Davies MRQ, Louw JH, et al:  Portacaval shunt in two patients with homozygous type II hyperlipoproteinaemia . South Afr Med J 50:239-242, 1976.
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Starzl TE, Putnam CW, Porter KA, et al:  Portal diversion for the treatment of glycogen storage disease in humans . Ann Surg 178:525-539, 1973.Article
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Starzl TE, Chase HP, Putnam CW, et al:  Follow-up of patient with portacaval shunt for the treatment of hyperlipidemia . Lancet 2:714-715, 1974.Article
Starzl TE, Chase HP, Putnam CW, et al:  Portacaval shunt in hyperlipidemia . Lancet 2:1263, 1974.Article
Putnam CW, Porter KA, Starzl TE:  Hepatic encephalopathy and light and electron micrographic changes of the baboon liver after portal diversion . Ann Surg 184:155-161, 1976.Article
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Coyle JJ, Schwartz MZ, Marubbio AT, et al:  The effect of portacaval shunt on plasma lipids and tissue cholesterol synthesis in the dog . Surgery 80:54-60, 1976.
Horak W, Gangl A, Funovics J, et al:  Effect of portacaval shunt and arterialization of the liver on bile acid metabolism . Gastroenterology 69:338-341, 1975.
Guzman IJ, Coyle JJ, Schneider PD, et al: The effect of selective visceral caval shunt on plasma lipids and cholesterol dynamics. Surgery to be published.
Edwards KDG, Herz R, Sealey JE, et al:  Lowering of blood pressure, plasma renin substrate, cholesterol and triglyceride by portacaval anastomosis in rats fed on a 60% sucrose/5% lard diet . Clin Sci Mol Med 51:1455-1465, 1976.
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Chase HP, Morris T:  Cholesterol metabolism following portacaval shunt in the pig . Atherosclerosis 24:141-148, 1976.Article
Carew TE, Saik RP, Johansen KH, et al:  Low density and high density lipoprotein turnover following portacaval shunt in swine . J Lipid Res 17:441-450, 1976.
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Bilheimer DW, Goldstein JL, Grundy SM, et al:  Reduction in cholesterol and low density lipoprotein synthesis in a patient with homozygous familial hypercholesterolemia . J Clin Invest 56:1420-1430, 1975.Article
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Eaton RP:  Glucagon and lipoprotein . Metabolism 25:1415-1418, 1976.Article