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March 1978

Epidural Injection of Local Anesthetic and Steroids for Relief of Pain Secondary to Herpes Zoster

Author Affiliations

From the Departments of Anesthesiology, University of Florida College of Medicine (Drs Perkins and Hanlon), and the Veterans Administration Hospital (Dr Perkins), Gainesville, Fla.

Arch Surg. 1978;113(3):253-254. doi:10.1001/archsurg.1978.01370150025003

• We treated 12 cases of cutaneous herpes zoster (HZ) with epidural bupivacaine and methylprednisolone acetate. Treatment was effective for HZ of less than seven weeks' duration. The course of HZ of greater than three months' duration (postherpetic neuralgia) was not improved. The administration of epidural bupivacaine plus methylprednisolone acetate was no more effective than when bupivacaine alone was used. Epidural injection of bupivacaine with or without methylprednisolone acetate is the treatment of choice for the pain of cutaneous HZ.

(Arch Surg 113:253-254, 1978)

De Moragas JH, Kierland RR:  The outcome of patients with herpes zoster . Arch Dermatol 75:193-196, 1957.Article
Eaglstein WH, Katz R, Brown JA:  The effects of early corticosteroid therapy on the skin eruption and pain of herpes zoster . JAMA 211:1681-1683, 1970.Article
Mani M, Keh L, Lee KN, et al: Sympathetic blockade for herpes zoster and post-herpetic neuralgia. Read before the annual meeting of the American Society of Anesthesiologists, San Francisco, Oct 13, 1976.