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March 1978

Bile Duct Adenomas as Liver Nodules

Author Affiliations

From the Laboratory (Drs Cho and Rullis) and Surgical (Dr Rogers) Services, Veterans Administration Hospital, and the Departments of Pathology (Drs Cho and Rullis) and Surgery (Dr Rogers), Upstate Medical Center, State University of New York, Syracuse.

Arch Surg. 1978;113(3):272-274. doi:10.1001/archsurg.1978.01370150044007

• Bile duct adenomas can be difficult to differentiate at laparotomy from small metastatic tumor nodules in the liver. This can present a problem to the pathologist and surgeon relative to the advisability of attempted curative vs palliative surgery. We report two such cases. Review of our autopsy materials shows the incidence of bile duct adenoma to be higher than usually reported. Even though they all present as grayish-white, firm nodules, usually frozen section will reveal the true nature of the lesion. Occasionally, however, the lesions with active bile duct proliferation can cause problems in diagnosis, even after such examination. Accurate diagnosis by recognition of the entity and its histological characteristics may be very important in the surgical treatment of patients.

(Arch Surg 113:272-274, 1978)

Mixter GG, Mixter GG Jr:  Liver nodules encountered at laparotomy: Significance and treatment . Ann Surg 138:230-239, 1953.Article
Zittel RX, Wegner G:  The differential diagnosis of benign cholangioma and liver metastases . Germ Med Mo 14:531-542, 1969.
Henson SW, Gray HK, Dockerty MB:  Benign tumors of the liver: I. Adenomas . Surg Gynecol Obstet 103:23-30, 1956.
Popper H, Schaffner F: Liver: Structure and Function . New York, McGraw-Hill Book Co Inc, 1957, pp 587-589.
Von Meyenburg H:  Uber die cystenleber . Beitr Pathol Anat 64:477-532, 1918.
Edmonson HA:  Tumors of the liver and intrahepatic bile ducts , in Atlas of Tumor Pathology . Armed Forces Institute of Pathology, 1958, section 7.
Chung EB:  Multiple bile duct hamartomas . Cancer 26:287-296, 1970.Article
Levin SE, Dail DH, Saik RP:  Bile duct adenomatosis of the liver . Arch Surg 108:880, 1974.Article
Ishak KG, Rabin L:  Benign tumors of the liver . Med Clin North Am 59:995-1013, 1975.
Homer LW, White HJ, Read RC:  Neoplastic transformation of v. Meyenberg complexes of the liver . J Pathol Bacteriol 96:499-502, 1968.Article