• Of 54 patients with soft-tissue sarcomas of the proximal part of the lower extremity, 2 patients (4%) were treated with amputation, while 52 patients (96%) were treated with limb-preserving resection. Adjuvant postoperative irradiation was applied selectively when the minimum margin was less than 2 cm (22 patients). Technical improvements in exposure, resection of involved vessels or nerve, and preservation of function permitted a high rate of limb salvage with satisfactory function. At a median follow-up of 30 months for those subjects still alive, the 5-year disease-free survival rate was 65%, and only 3 patients (6%) had had a local recurrence.
(Arch Surg. 1989;124:1297-1300)
Karakousis CP, Emrich LJ, Vesper DS. Soft-Tissue Sarcomas of the Proximal Lower Extremity. Arch Surg. 1989;124(11):1297-1300. doi:10.1001/archsurg.1989.01410110055011