[Skip to Content]
Access to paid content on this site is currently suspended due to excessive activity being detected from your IP address Please contact the publisher to request reinstatement.
Sign In
Individual Sign In
Create an Account
Institutional Sign In
OpenAthens Shibboleth
[Skip to Content Landing]
October 1996

Usefulness of Ultrasound-Guided, Fine-needle Aspiration Biopsy for Palpable Breast Tumors

Author Affiliations

From the Second Department of Surgery, Hyogo College of Medicine, Nishinomiya, Japan (Drs Hatada, Okada, and Utsunomiya), and the Department of Surgery, Kobe-Kaisei Hospital, Kobe, Japan (Drs Aoki and Nakai).

Arch Surg. 1996;131(10):1095-1098. doi:10.1001/archsurg.1996.01430220089020

Objective:  To investigate whether ultrasound (US) guidance improves the sensitivity of fine-needle aspiration biopsy (FNAB) in patients with palpable breast tumors.

Design:  A retrospective study.

Setting:  A university hospital.

Patients:  A total of 107 patients with breast tumors (114 lesions) underwent US-guided FNAB and 138 patients (143 lesions) underwent FNAB guided by palpation (standard FNAB).

Main Outcome Measures:  The diagnoses obtained by FNAB were compared with the surgical findings and the diagnostic value of US-guided FNAB was evaluated.

Results:  The sensitivity of US-guided FNAB was 89.3%, the specificity was 82.9%, and the accuracy was 86.9%. In contrast, the sensitivity of standard FNAB was 61.1%, the specificity was 73.3%, and the accuracy was 65.0%. For breast tumors 2.0 cm or less in diameter, the sensitivity and accuracy of US-guided FNAB were significantly higher than those of standard FNAB.

Conclusion:  Ultrasound-guided FNAB can improve the preoperative diagnosis of breast cancer, especially in patients with tumors that are 2 cm or less in diameter.Arch Surg. 1996;131:1095-1098

Martin HE, Ellis EB.  Biopsy by needle puncture and aspiration . Ann Surg . 1930; 62:2169-2181.
Stewart FW.  The diagnosis of tumors by aspiration . Am J Pathol . 1933;9:801-812.
Wild JJ, Neal D.  Use of high frequency ultrasonic waves for detecting changes of texture in living tissues . Lancet . 1951;1:655-657.Article
Fornage BD, Faroux MJ, Simatos A.  Breast masses: US-guided fine-needle aspiration biopsy . Radiology . 1987;162:409-414.Article
Fornage BD.  Guided fine-needle aspiration biopsy of nonpalpable breast lesions: calculation of accuracy values . Radiology . 1990;177:884-885.Article
Wilson SL, Ehrmann RL.  The cytologic diagnosis of breast aspirations . Acta Cytol . 1978;22:470-475.
Wanebo HJ, Feldman PS, Wilhelm MC, et al.  Fine needle aspiration cytology in lieu of open biopsy in management of primary breast cancer . Ann Surg . 1984; 199:569-578.Article
Abele JS, Miller TR, Goodson WH Ill, et al.  Fine-needle aspiration of palpable breast masses: a program for staged implementation . Arch Surg . 1983;118:859-863.Article
Grant C, Goellner JR, Welch JS, et al.  Fine-needle aspiration of the breast . Mayo Clin Proc . 1986;61:377-381.Article
Hermansen C, Poulsen HS, Jensen J, et al.  Diagnostic reliability of combined physical examination, mammography and fine-needle puncture ('triple-test') in breast tumors: a prospective study . Cancer . 1987;60:1866-1871.Article
Kreuzer G, Boquoi E.  Aspiration biopsy cytology, mammography and clinical exploration: a modern set-up in diagnosis of tumors of the breast . Acta Cytol . 1976;20:319-323.
Thomas JM, Fizharris BM, Redding WH, et al.  Clinical examination, xeromammography and fine-needle aspiration cytology in diagnosis of breast tumors . BMJ . 1978;2:1139-1141.Article
Fornage BD, Sneige N, Faroux M J, et al.  Sonographic appearance and ultrasound-guided fine-needle aspiration biopsy of breast carcinomas smaller than 1 cm3 . J Ultrasound Med . 1990;9:559-568.
Barbano PR, Reali G.  Ultrasound-guided fine-needle aspiration of impalpable breast nodules . Tumori . 1993;79:418-421.
Gordon PB, Goldenberg SL, Chan NHL.  Solid breast lesions: diagnosis with US-guided fine-needle aspiration biopsy . Radiology . 1993;189:573-580.Article
Reading CC, Charboneau JW, James E M, et al.  Sonographically guided percutaneous biopsy of small (3 cm or less) masses . AJR Am J Roentgenol . 1988; 151:189-192.Article