AMA Publishing Group: Depression and Dysthymia Topic Collection http://pubs.jamanetwork.com/ en-us Mon, 13 May 2013 00:00:00 GMT Tue, 14 May 2013 18:44:40 GMT Silverchair editor@pubs.jamanetwork.com webmaster@pubs.jamanetwork.com Serotonin Reuptake Inhibitor Use, Depression, and Long-Term Outcomes After an Acute Coronary Syndrome: A Prospective Cohort Study http://pubs.jamanetwork.com/article.aspx?articleID=1687523 Mon, 13 May 2013 00:00:00 GMT Rieckmann N, Kronish IM, Shapiro PA, et al. <span class="paragraphSection">Depression is highly prevalent among patients with coronary heart disease. Selective serotonin reuptake inhibitors (SSRIs) are recommended as first-line antidepressant treatments for this population. Whereas there is a long-standing notion that SSRIs may improve cardiac disease prognosis by inhibiting platelet aggregation, SSRI use may also worsen prognosis by increasing bleeding or increasing the risk for arrhythmia.</span> 1 2 10.1001/jamainternmed.2013.910 http://pubs.jamanetwork.com/article.aspx?articleID=1687523