AMA Publishing Group: Genetic Counseling Topic Collection http://pubs.jamanetwork.com/ en-us Wed, 10 Apr 2013 00:00:00 GMT Wed, 10 Apr 2013 22:44:53 GMT Silverchair editor@pubs.jamanetwork.com webmaster@pubs.jamanetwork.com The Indispensable Role of Professional Judgment in Genomic Medicine Professional Judgment in Genomic Medicine http://pubs.jamanetwork.com/article.aspx?articleID=1677382 Wed, 10 Apr 2013 00:00:00 GMT McGuire AL, McCullough LB, Evans JP. <span class="paragraphSection">Whole-genome sequencing and whole-exome sequencing (WGS/WES) have become increasingly affordable and accessible to individuals. There are currently 3 main pathways through which a person can receive WGS/WES: as a research participant in a genomic study; through a direct-to-consumer personal genome company; or as part of clinical care. In the research context, the extent to which findings from WGS/WES are communicated to study participants and used to inform their clinical care is a topic of much debate, but guidelines suggest that investigators may have an obligation to offer at least some results to study participants.</span> 309 14 1465 1466 10.1001/jama.2013.1438 http://pubs.jamanetwork.com/article.aspx?articleID=1677382