This systematic review characterizes associations between 3 aspects of antibiotic therapy (optimal time to antibiotic initiation, initial antibiotic selection, and criteria for the transition from intravenous to oral therapy) and short-term mortality in adults hospitalized with community-acquired pneumonia.
This randomized trial compares the efficacy of varenicline, nicotine patch, and combination nicotine replacement therapy (patch plus lozenges) on smoking abstinence at 26 weeks among adults interested in quitting smoking.
This randomized trial compares the effects of endovascular revascularization and supervised exercise vs supervised exercise alone on walking distance and quality of life among patients with peripheral artery disease and intermittent claudication.
This cohort study reports the effects of an oral fixed-dose regimen of daclatasvir, asunaprevir, and beclabuvir on sustained virologic response in patients without cirrhosis who had chronic hepatitis C virus infection.
Gershon and coauthors conducted a population-based, longitudinal cohort study to estimate the long-term benefits of combination long-acting β-agonists (LABAs) and inhaled corticosteroids compared with LABAs alone among patients with chronic obstructive pulmonary disease. Calverley comments in an Editorial.
Ebberts and colleagues compare the efficacy and safety of varenicline and sustained-release bupropion vs varenicline alone in 506 adult cigarette smokers in a randomized, blinded, placebo-controlled, 12-week clinical trial (52-week follow-up) at 3 centers from October 2009 through April 2013.
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