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  • New Heart Failure Guidelines Released

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    JAMA. 2005; 294(8):892-892. doi: 10.1001/jama.294.8.892
  • Effect of Oral Iron Repletion on Exercise Capacity in Patients With Heart Failure With Reduced Ejection Fraction and Iron Deficiency: The IRONOUT HF Randomized Clinical Trial

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    JAMA. 2017; 317(19):1958-1966. doi: 10.1001/jama.2017.5427

    This randomized clinical trial investigates the efficacy of oral iron supplementation for improvement of exercise capacity in adult patients with heart failure with reduced left ventricular ejection fraction.

  • Association Between Tracheal Intubation During Adult In-Hospital Cardiac Arrest and Survival

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    JAMA. 2017; 317(5):494-506. doi: 10.1001/jama.2016.20165

    This cohort study uses data from the Get With The Guidelines–Resuscitation registry to investigate the association between tracheal intubation during adult in-hospital cardiac arrest and survival to hospital discharge.

  • Association Between Tracheal Intubation During Pediatric In-Hospital Cardiac Arrest and Survival

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    JAMA. 2016; 316(17):1786-1797. doi: 10.1001/jama.2016.14486

    This cohort study using data from the Get With The Guidelines–Resuscitation quality improvement registry to investigate the association between intubation during in-hospital pediatric cardiac arrest and survival to hospital discharge.

  • Association Between Therapeutic Hypothermia and Survival After In-Hospital Cardiac Arrest

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    JAMA. 2016; 316(13):1375-1382. doi: 10.1001/jama.2016.14380

    This cohort study uses Get With the Guidelines–Resuscitation registry data to evaluate the association between use of therapeutic hypothermia and survival after in-hospital cardiac arrest.

  • Low-Dose Dopamine or Low-Dose Nesiritide in Acute Heart Failure With Renal Dysfunction: The ROSE Acute Heart Failure Randomized Trial

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    JAMA. 2013; 310(23):2533-2543. doi: 10.1001/jama.2013.282190

    To examine the effect of low-dose dopamine or low-dose nesiritide added to diuretic therapy on decongestion and renal function in patients with acute heart failure, Chen and coauthors conducted a randomized clinical trial in 360 patients with heart failure and renal dysfunction in North America.

  • Alignment of Do-Not-Resuscitate Status With Patients’ Likelihood of Favorable Neurological Survival After In-Hospital Cardiac Arrest

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    JAMA. 2015; 314(12):1264-1271. doi: 10.1001/jama.2015.11069

    This study of patients successfully resuscitated after an inpatient cardiac arrest assessed whether their postevent do-not-resuscitate staus was appropriate given their neurological prognosis.

  • Clinical Implications of QRS Duration in Patients Hospitalized With Worsening Heart Failure and Reduced Left Ventricular Ejection Fraction

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    JAMA. 2008; 299(22):2656-2666. doi: 10.1001/jama.299.22.2656
  • Short-term Intravenous Milrinone for Acute Exacerbation of Chronic Heart Failure: A Randomized Controlled Trial

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    JAMA. 2002; 287(12):1541-1547. doi: 10.1001/jama.287.12.1541
  • Effect of Vitamin D 3 on Asthma Treatment Failures in Adults With Symptomatic Asthma and Lower Vitamin D Levels: The VIDA Randomized Clinical Trial

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    JAMA. 2014; 311(20):2083-2091. doi: 10.1001/jama.2014.5052

    Castro and coauthors report the effect of vitamin D3 supplementation on asthma treatment failures in adults with symptomatic asthma and lower vitamin D levels.

  • Comparison of Physician-, Biomarker-, and Symptom-Based Strategies for Adjustment of Inhaled Corticosteroid Therapy in Adults With Asthma: The BASALT Randomized Controlled Trial

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    JAMA. 2012; 308(10):987-997. doi: 10.1001/2012.jama.10893
    Calhoun and coauthors compared physician-, biomarker-, and symptom-based strategies for adjustment of inhaled corticosteroid therapy in adults with asthma in the Best Adjustment Strategy for Asthma in the Long Term (BASALT) randomized controlled trial. In an accompanying Editorial, Reibman and O’Connor discuss inhaled corticosteroid dose adjustment in mild persistent asthma.
  • Association of Hospital Primary Angioplasty Volume in ST-Segment Elevation Myocardial Infarction With Quality and Outcomes

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    JAMA. 2009; 302(20):2207-2213. doi: 10.1001/jama.2009.1715
  • Management of Heart Failure: I. Pharmacologic Treatment

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    JAMA. 1994; 272(17):1361-1366. doi: 10.1001/jama.1994.03520170071039
  • Early Administration of Azithromycin and Prevention of Severe Lower Respiratory Tract Illnesses in Preschool Children With a History of Such Illnesses: A Randomized Clinical Trial

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    JAMA. 2015; 314(19):2034-2044. doi: 10.1001/jama.2015.13896

    This randomized trial evaluates if early administration of azithromycin, started prior to the onset of severe lower respiratory tract illness (LRTI) symptoms, in preschool children with recurrent severe LRTIs can prevent the progression of these episodes.

  • Complications Associated With Implantable Cardioverter-Defibrillator Replacement in Response to Device Advisories

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    JAMA. 2006; 295(16):1907-1911. doi: 10.1001/jama.295.16.1907
  • Biomarker-Guided vs Guideline-Directed Titration of Medical Therapy for Heart Failure

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    JAMA. 2017; 318(8):707-708. doi: 10.1001/jama.2017.10540
  • Initial Trophic vs Full Enteral Feeding in Patients With Acute Lung Injury: The EDEN Randomized Trial

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    JAMA. 2012; 307(8):795-803. doi: 10.1001/jama.2012.137
  • Inhaled Corticosteroid Reduction and Elimination in Patients With Persistent Asthma Receiving Salmeterol: A Randomized Controlled Trial

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    JAMA. 2001; 285(20):2594-2603. doi: 10.1001/jama.285.20.2594