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  • Anaplastic Large-Cell Lymphoma in Women With Breast Implants

    Abstract Full Text
    free access
    JAMA. 2008; 300(17):2030-2035. doi: 10.1001/jama.2008.585
  • JAMA November 5, 2008

    Figure: Anaplastic Large-Cell Lymphoma in the Fibrous Capsule of a Breast Implant

    A, Overview of tumor in patient 9 (original magnification ×20) and B, cellular detail at a higher magnification (original magnification ×400). C, The tumor cells show uniform expression of CD30 (original magnification ×400) and D, CD5 expression in some tumor cells (original magnification ×400). The presence of CD30 on the tumor cells and CD5 protein on tumor cells and reactive T-cells is visualized by the brown chromogen. Immunohistochemistry was performed with BerH2 monoclonal antibody for CD30 (DAKO, Glostrup, Denmark) and CD5-4C7 antibody for CD5 (Novocastra, Newcastle Upon Tyne, England), biotin peroxidase detection system (Powervision, Immunologic, Duiven, the Netherlands), diaminobenxidine as chromogen, and hematoxylin counterstain.