Showing 1 – 20 of 616
Relevance | Newest | Oldest |
  • Delirium in Older Persons: Advances in Diagnosis and Treatment

    Abstract Full Text
    is active quiz
    JAMA. 2017; 318(12):1161-1174. doi: 10.1001/jama.2017.12067

    This narrative review summarizes recent advances in the prevention, diagnosis, and treatment of delirium and highlights critical areas for future research.

  • JAMA August 15, 2017

    Figure 3: Proportion of Participants With Non–Insulin-Dependent Type 2 Diabetes With a Reduction in Glucose-Lowering Medication From Baseline in the Lifestyle vs Standard Care Groups

    Error bars indicate 95% CIs. If the prespecified treatment target was reached at the medical consultation, the pharmacological treatment was halved. If unchanged values or an additional reduction was observed at the following medical consultation, the medical treatment was paused.
  • JAMA June 20, 2017

    Figure 2: Literature Search Flow Diagram

    Details for reasons for exclusion are as follows. Relevance: Study aim not relevant. Setting: Study was not conducted in a setting or country relevant to US primary care. Comparative effectiveness: Study did not have a control group. Outcomes: Study did not have relevant outcomes or had incomplete outcomes. Population: Study was not conducted in children and adolescents aged 2 to 18 years. Intervention: Study used an excluded intervention/screening approach. Design: Study did not use an included design. Quality: Study did not meet criteria for fair or good quality (ie, was poor quality) using study-design specific criteria developed by the US Preventive Services Task Force for randomized clinical trials; the criteria and definitions of good, fair, poor are provided in eTable 1 in the Supplement. Language: Study was published in a non-English language. Publication date: Article was published before 1985. Unable to locate: Library services could not locate article in which study was published.aThree pharmacotherapy studies included for harms only, because weight outcomes were reported at less than 6 months.
  • Management of Depression in Older Adults: A Review

    Abstract Full Text
    is active quiz
    JAMA. 2017; 317(20):2114-2122. doi: 10.1001/jama.2017.5706

    This review offers guidance on medical and psychotherapeutic treatment options available for older frail patients with depression and who are taking several types of medications.

  • JAMA September 13, 2016

    Figure 1: Use of Pharmacological Therapies at Hospital Discharge and Use of an Invasive Coronary Strategy per Month, 2003-2013

    ACE indicates angiotensin-converting enzyme; ARB, angiotensin receptor blockers. Invasive coronary strategies included coronary angiography, percutaneous coronary intervention, and coronary artery bypass graft surgery. Curves were fitted using local polynomial smoothing. Median and range of patients per month for each year are based on complete case data for discharge medications and treatment only. Numbers of patients per month with use of pharmacological therapies ranged from 1092 to 3824 across all time periods. Numbers of patients per month with use of an invasive coronary strategy ranged from 1048 to 3591 across all time periods.
  • Association of Clinical Factors and Therapeutic Strategies With Improvements in Survival Following Non–ST-Elevation Myocardial Infarction, 2003-2013

    Abstract Full Text
    free access is active quiz
    JAMA. 2016; 316(10):1073-1082. doi: 10.1001/jama.2016.10766

    This population epidemiology study uses UK clinical database data to investigate trends in prevalence of cardiovascular risk factors and management strategies and their association with trends in mortality among patients with non–ST-elevation myocardial infarction (NSTEMI) between 2003 and 2013.

  • Primary Care Screening and Treatment for Latent Tuberculosis Infection in Adults: Evidence Report and Systematic Review for the US Preventive Services Task Force

    Abstract Full Text
    free access is active quiz
    JAMA. 2016; 316(9):970-983. doi: 10.1001/jama.2016.10357

    This Evidence Report to support the 2016 update of the US Preventive Services Task Force Recommendation Statement on primary care screening for and treatment of latent tuberculosis infection in adults summarizes evidence on screening test accuracy and benefits and harms of screening and treatment.

  • Tobacco Smoking Cessation in Adults and Pregnant Women: Behavioral and Pharmacotherapy Interventions

    Abstract Full Text
    JAMA. 2016; 315(18):2011-2012. doi: 10.1001/jama.2016.2535

    This JAMA Clinical Guidelines Synopsis summarizes the US Preventive Services Task Force’s 2015 guideline on screening for tobacco smoking and provision of cessation interventions.

  • JAMA April 19, 2016

    Figure 3: Hazard Ratios for the Primary End Point in Prespecified Subgroups of Interest at 12 Weeks After Randomization

    Hazard ratios for the primary end point (cardiovascular death, myocardial infarction [MI], or severe recurrent ischemia leading to urgent revascularization) with losmapimod vs placebo in various subgroups at 12 weeks. Predictors of cardiovascular risk included age 60 years or older, prior MI, prior coronary artery bypass graft (CABG) surgery, non–ST elevation with ST-segment depression, diabetes mellitus requiring pharmacotherapy or coexistent arterial disease in at least 1 other peripheral territory. PCI indicates percutaneous coronary intervention. Data marker sizes are weighted based on number of individuals in each subgroup.
  • Effects of Nicotine Patch vs Varenicline vs Combination Nicotine Replacement Therapy on Smoking Cessation at 26 Weeks: A Randomized Clinical Trial

    Abstract Full Text
    free access
    JAMA. 2016; 315(4):371-379. doi: 10.1001/jama.2015.19284

    This randomized trial compares the efficacy of varenicline, nicotine patch, and combination nicotine replacement therapy (patch plus lozenges) on smoking abstinence at 26 weeks among adults interested in quitting smoking.

  • Pharmacological Interventions for Sleepiness and Sleep Disturbances Caused by Shift Work

    Abstract Full Text
    JAMA. 2015; 313(9):961-962. doi: 10.1001/jama.2014.18422

    This JAMA Clinical Evidence Synopsis summarizes data from a Cochrane review of pharmacological interventions for sleepiness and sleep disturbances caused by shift work.

  • Sustained Care Intervention and Postdischarge Smoking Cessation Among Hospitalized Adults: A Randomized Clinical Trial

    Abstract Full Text
    free access is expired quiz has multimedia
    JAMA. 2014; 312(7):719-728. doi: 10.1001/jama.2014.9237

    Rigotti and coauthors report the results from a randomized clinical trial on the effect of a sustained care intervention on postdischarge smoking cessation among hospitalized adults.

  • JAMA July 16, 2014

    Figure 1: Adjusted Odds Ratios of 30-Day Major Adverse Cardiac Events Stratified by Stroke Prior to Surgery and Time Elapsed Between Stroke and Surgery

    MACE indicates major adverse cardiac events (acute myocardial infarction, ischemic stroke, or cardiovascular death). Adjusted for sex, age, body mass index, all comorbidities, all pharmacotherapy, surgery group, and surgery risk.
  • Pharmacotherapy for Adults With Alcohol Use Disorders in Outpatient Settings: A Systematic Review and Meta-analysis

    Abstract Full Text
    free access is expired quiz
    JAMA. 2014; 311(18):1889-1900. doi: 10.1001/jama.2014.3628

    Jonas and coauthors conducted a systematic review and meta-analysis of the benefits and harms of medications for adults with alcohol use disorders that included 122 randomized clinical trials and 1 cohort study (22 803 participants). In an Editorial, Bradley and Kivlahan discuss the importance of patient-centered care and shared decision making for patients with alcohol use disorders.

  • Pharmacological Treatment of Parkinson Disease: A Review

    Abstract Full Text
    is expired quiz
    JAMA. 2014; 311(16):1670-1683. doi: 10.1001/jama.2014.3654

    Connelly and Lang provide an evidence-based review of the initial pharmacological management of the classical motor symptoms of Parkinson disease and describe the management of medication-related motor complications as well as selected nonmotor symptoms of Parkinson disease.

  • JAMA April 9, 2014

    Figure: Treatment-Eligible Hypertension and Adults With Above-Goal BP According to JNC 7 and the 2014 Blood Pressure Guideline

    Proportion of all adults aged 18-59 years and aged 60 years or older considered eligible for medication treatment, and the proportion of adults with treatment-eligible hypertension who met BP goals according to JNC 7 and the 2014 blood pressure guideline. Medication-eligible hypertension is defined as receiving therapy or above goal for each guideline. NHANES indicates National Health and Nutrition Examination Survey. Percentages and 95% CIs (error bars) are weighted.
  • 2014 Evidence-Based Guideline for the Management of High Blood Pressure in Adults: Report From the Panel Members Appointed to the Eighth Joint National Committee (JNC 8)

    Abstract Full Text
    free access is expired quiz
    JAMA. 2014; 311(5):507-520. doi: 10.1001/jama.2013.284427

    In the report from the panel members appointed to the Eighth Joint National Committee (JNC 8), the guideline authors provide evidence-based recommendations for the management of hypertension including specific goals by age, race, and comorbidities.

  • New Drugs—Miracles or Mirages?

    Abstract Full Text
    JAMA. 2014; 311(4):423-423. doi: 10.1001/jama.2013.279299
  • Pharmacological Treatments for Smoking Cessation

    Abstract Full Text
    JAMA. 2014; 311(2):193-194. doi: 10.1001/jama.2013.283787
  • The Medical Letter in JAMA

    Abstract Full Text
    JAMA. 2014; 311(2):144-144. doi: 10.1001/jama.2013.283819