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  • No Perfect Choice

    Abstract Full Text
    JAMA. 2017; 318(1):29-30. doi: 10.1001/jama.2017.5523
  • Preeclampsia Screening: Evidence Report and Systematic Review for the US Preventive Services Task Force

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    JAMA. 2017; 317(16):1668-1683. doi: 10.1001/jama.2016.18315

    This Evidence Report and systematic review to support the 2017 US Preventive Services Task Force Recommendation Statement on preeclampsia screening summarizes the benefits, accuracy, and harms of screening for preeclampsia.

  • Seven-Year Follow-up of Children Born to Women in a Randomized Trial of Prenatal DHA Supplementation

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    JAMA. 2017; 317(11):1173-1175. doi: 10.1001/jama.2016.21303

    This study reports neurodevelopmental outcomes at 7 years of children whose mothers participated in a randomized trial of docosahexaenoic acid supplementation during pregnancy to improve their child’s intelligence.

  • Where to Draw the Boundaries for Prenatal Carrier Screening

    Abstract Full Text
    JAMA. 2016; 316(7):717-719. doi: 10.1001/jama.2016.10888
  • Risk of Prenatal Opioid Prescribing

    Abstract Full Text
    JAMA. 2016; 315(22):2390-2390. doi: 10.1001/jama.2016.6962
  • Effect of Prenatal Supplementation With Vitamin D on Asthma or Recurrent Wheezing in Offspring by Age 3 Years: The VDAART Randomized Clinical Trial

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    JAMA. 2016; 315(4):362-370. doi: 10.1001/jama.2015.18589

    This randomized clinical trial assesses whether high-dose vitamin D supplementation during the third trimester of women at high risk of having children with asthma reduces asthma or recurrent wheeze in their offspring.

  • Effect of Vitamin D 3 Supplementation During Pregnancy on Risk of Persistent Wheeze in the Offspring: A Randomized Clinical Trial

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    JAMA. 2016; 315(4):353-361. doi: 10.1001/jama.2015.18318

    This randomized clinical trial compares the effects of vitamin D3 supplementation vs placebo during women’s third trimester of pregnancy on age at onset of persistent wheeze in the children in the first 3 years of life.

  • Comparison of Intended Scope of Practice for Family Medicine Residents With Reported Scope of Practice Among Practicing Family Physicians

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    JAMA. 2015; 314(22):2364-2372. doi: 10.1001/jama.2015.13734

    This cross-sectional survey study compares the intended scope of practice reported by family medicine residents with the actual scope of practice reported by recertifying family physicians on the 2014 American Board of Family Medicine examination registration questionnaire.

  • JAMA September 8, 2015

    Figure 1: Care Practices for Infants Born at Gestational Ages 22 through 28 Weeks

    Circles indicate the percent of infants born each year who received the practice, the smoothed curve shows the trend, and shading indicates the 95% CI for the curve. Shading is not visible where CIs are close to values on the curve. Percentages are among all infants except those for postnatal steroids (which include only infants who survived >12 hours; this outcome was not collected for infants who died ≤12 hours of age). Adjusted relative risks (RRs) are based on infants of all gestational ages and are shown for outcomes for which the year-gestational age interaction was not significant. When the year-gestational age interaction was significant, graphs and RRs are shown for each gestational age in eFigures 1-4 in the Supplement. RRs for the change per year were adjusted for study center, maternal race/ethnicity, infant gestational age, small size for gestational age, and sex. Total number of infants (mean [range] per year): 34 576 (1728 [1214-2022]) for antenatal steroids; 34 531 (1726 [1210-2020]) for antenatal antibiotics; 34 611 (1730 [1213-2024]) for cesarean delivery; 34 611 (1730 [1214-2024]) for intubation; 34 599 (1729 [1214-2023]) for surfactant; and 30 645 (1532 [1036-1802]) for postnatal steroids.
  • Trends in Care Practices, Morbidity, and Mortality of Extremely Preterm Neonates, 1993-2012

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    JAMA. 2015; 314(10):1039-1051. doi: 10.1001/jama.2015.10244

    This population epidemiology study used neonatal registry data to characterize trends in maternal and neonatal care, and morbidity and mortality of extremely preterm infants between 1993 and 2012.

  • Antenatal Iron Use in Malaria Endemic Settings: Evidence of Safety?

    Abstract Full Text
    JAMA. 2015; 314(10):1003-1005. doi: 10.1001/jama.2015.10032
  • Effect of Daily Antenatal Iron Supplementation on Plasmodium Infection in Kenyan Women: A Randomized Clinical Trial

    Abstract Full Text
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    JAMA. 2015; 314(10):1009-1020. doi: 10.1001/jama.2015.9496

    This randomized trial compares the effects of daily iron supplementation vs placebo on maternal Plasmodium infection risk and neonatal outcomes among pregnant women living in a malaria endemic area.

  • JAMA August 11, 2015

    Figure 1: Adverse Outcome Rates by Deciles of Percentage of Time With Hypoxemia or Bradycardia

    The 4 panels on the left show the relationships between the percentage of time with pulse oximeter oxygen saturation (Spo2) of less than 80% and the primary outcome of late death or disability as well as the 3 secondary outcomes. Regression models were fitted with the respective dichotomous outcome as the dependent variable and percentage of time with hypoxemia as the continuous independent variable. To visualize the fit of these models, the data were subdivided into deciles of percentage of time with hypoxemia and the observed outcome rate plotted against the mean percentage of time with hypoxemia for each decile. The 4 panels on the right show the equivalent relationships between the 4 outcomes and the independent variable percentage of time with pulse rate of less than 80/min. The black curves show the fit of the unadjusted logistic regression models. The blue (A) or orange (B) curves show the fit of the logistic models after adjustment for gestational age, sex, primary caregiver level of educational attainment, use of antenatal corticosteroids, multiple birth, and study center. Zero to 25% probability of outcome is shown in blue on each y-axis. Risk gradient refers to the model parameter associated with the exposure variable (percentage of time with Spo2 <80% or pulse rate <80/min). The significance of each risk gradient was computed from the estimated coefficient associated with the respective exposure variable (Wald χ2) for the adjusted logistic model. The raw data for the decile points are provided in eTable 1 in the Supplement. Sample sizes varied by outcome (eTable 1). For the primary outcome of late death or disability, 972 infants were included in the analyses for both hypoxemia and bradycardia.
  • Legislation Introduced to Set Higher Maternity Care Standards

    Abstract Full Text
    JAMA. 2015; 313(14):1409-1409. doi: 10.1001/jama.2015.3008
  • Effect of Maternal Multiple Micronutrient vs Iron–Folic Acid Supplementation on Infant Mortality and Adverse Birth Outcomes in Rural Bangladesh: The JiVitA-3 Randomized Trial

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    JAMA. 2014; 312(24):2649-2658. doi: 10.1001/jama.2014.16819

    This randomized trial reports that antenatal multiple micronutrient compared with iron–folic acid supplementation did not reduce infant mortality to age 6 months but resulted in a non–statistically significant reduction in stillbirths and significant reductions in preterm births and low birth weight.

  • Effect of Enhanced Information, Values Clarification, and Removal of Financial Barriers on Use of Prenatal Genetic Testing: A Randomized Clinical Trial

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    JAMA. 2014; 312(12):1210-1217. doi: 10.1001/jama.2014.11479

    This randomized trial reports less prenatal testing and more informed choices among pregnant women with access to a computerized, interactive, decision-support guide and access to prenatal testing with no out-of-pocket expenses vs those receiving care per current guidelines.

  • Personalized Genomic Medicine and Prenatal Genetic Testing

    Abstract Full Text
    JAMA. 2014; 312(12):1203-1205. doi: 10.1001/jama.2014.12205
  • School-age Outcomes of Very Preterm Infants After Antenatal Treatment With Magnesium Sulfate vs Placebo

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    JAMA. 2014; 312(11):1105-1113. doi: 10.1001/jama.2014.11189

    This follow-up study to a randomized trial determined that antenatal magnesium sulfate was not associated with improved neurological, cognitive, academic, or behavioral outcomes at school age.

  • Do Women See Specialists for Routine Prenatal Care?

    Abstract Full Text
    JAMA. 2014; 311(20):2058-2058. doi: 10.1001/jama.2014.5116
  • Four-Year Follow-up of Children Born to Women in a Randomized Trial of Prenatal DHA Supplementation

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    JAMA. 2014; 311(17):1802-1804. doi: 10.1001/jama.2014.2194