Left Ventricular Hypertrophy | Cardiology | JAMA Network
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JAMA Patient Page
November 17, 2004

Left Ventricular Hypertrophy

JAMA. 2004;292(19):2430. doi:10.1001/jama.292.19.2430

The major pumping chamber of the heart is the left ventricle. This heart chamber pumps oxygenated blood into the aorta, the large blood vessel that delivers blood to the body's tissues. If the left ventricle has to work too hard, its muscle hypertrophies (enlarges) and becomes thick. This is called left ventricular hypertrophy (LVH). Because of the increased thickness, blood supply to the muscle itself may become inadequate. This can lead to cardiac ischemia (not enough blood and oxygen at the tissue level), myocardial infarction (heart attack), or heart failure. The November 17, 2004, issue of JAMA includes several articles about reducing the risks of heart failure and death from LVH by treating high blood pressure.