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Stong BC, Jacono AA. Effect of Perioperative Hyperbaric Oxygen on Bruising in Face-lifts. Arch Facial Plast Surg. 2010;12(5):356–358. doi:10.1001/archfacial.2010.66
Hyperbaric oxygen (HBO) therapy has been used for wound healing for many years. It increases the ability of blood to upload, carry, and deliver oxygen to tissue. The mechanism by which oxygen acts on wound beds is multifactorial, but includes improved oxygen delivery to relatively hypoxic and avascular tissue and increases free radical scavengers to prevent and reduce oxidative stress and tissue injury. The final common pathway for wounds treated with HBO therapy is improved and more rapid wound healing.
Wound healing is a primary interest of both patients and the collective health care industry. Physicians modify surgical techniques, pharmaceutical companies spend millions of dollars on research and development, and patients use anecdotal home remedies in their care to facilitate a more rapid recovery. One of the most challenging aspects in evaluation of wound healing has been developing an inexpensive, easy-to-use, objective measure to assess outcomes. Subtle variability between photographs may be imperceptible to even the most trained eye, resulting in inaccuracies when grading outcomes.1-3 Seeley et al4 developed digital photographic analysis of ecchymosis of the skin flaps of patients who undergo face-lift procedures using nonsurgical internal skin controls to reduce intraobserver variability.
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