Explore the latest in sarcomas, including recent advances in classification, diagnosis, and medical and surgical management.
This nonrandomized clinical trial investigates the safety and effectiveness of trabectedin with radiotherapy in patients with myxoid liposarcoma.
This ancillary analysis of 2 randomized clinical trials of patients receiving neoadjuvant chemoradiotherapy or preoperative image-guided radiotherapy examines the prognostic significance of pathologic complete response on survival outcomes in patients with soft tissue sarcoma receiving neoadjuvant chemoradiotherapy.
A man in his 50s with a history of mycosis fungoides presents with bleeding wounds and nodules on the bilateral hips and forearms. What is your diagnosis?
This case report describes a large, purpuric plaque involving most of the right face with associated periorbital swelling but without ulceration.
This case report describes a man in his 60s who was referred to the department of dermatology for further evaluation of a lesion on the nose.
This case report describes a man with untreated HIV infection who presented with Kaposi sarcoma caruncular lesions that resolved completely with medical treatment.
This phase 2 nonrandomized clinical trial examines the association of cabazitaxel treatment for patients with advanced dedifferentiated liposarcoma with progression-free survival.
This case report describes a man in his 70s who presented with a bilobed, cylindrical mucosal mass that had been expelled from his mouth after an episode of nausea and violent vomiting.
This case report describes a Mediterranean HIV-negative man in his 60s with hypertension, osteoporosis, a history of flaccid paralysis after polio syndrome, and a 4-year history of progressive development of purplish, reddish cutaneous plaques and nodules limited to the lower limbs.
An adolescent girl presented with an asymptomatic slightly reddish verrucous plaque on the right temple; the skin lesion was nail sized when first noticed 1½ years ago, then gradually developed over the previous 8 months. What is your diagnosis?
A 32-year-old woman with fever, flulike symptoms, and altered mental status developed sudden-onset blurry vision in her right eye. Following intravenous antibiotics and antivirals, laboratory and imaging results were negative and her mental status improved but blurry vision persisted in the right eye. What would you do next?
This case report describes a diagnosis of orbital embryonal rhabdomyosarcoma in a man aged 22 years who presented with eyelid ptosis and diplopia.
This randomized clinical trial investigates whether carotuximab plus pazopanib improves progression-free survival vs pazopanib alone in adult patients with advanced angiosarcoma.
A 33-year-old woman with a history of hereditary bilateral retinoblastoma as an infant presents with 1 week of right lower extremity swelling. What is your diagnosis?
This cohort study investigates variations in treatment management in young adults vs older adults with extremity soft-tissue sarcomas.
This genetic association study examines immune-related gene expression in osteosarcoma samples from The Cancer Genome Atlas project and assesses the association of gene expression profiles with survival outcomes.
This case report describes diffuse yellow pigmentation and scattered ecchymotic lesions.
A 39-year-old woman with alveolar rhabdomyosarcoma and bone metastases presents with lower back pain. The treatment regimen recently was changed to gemcitabine hydrochloride and docetaxel, and imaging shows edema in both psoas muscles. What is your diagnosis?
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