Explore the latest in sarcomas, including recent advances in classification, diagnosis, and medical and surgical management.
A young man with a history of adenosine deaminase–deficient severe combined immunodeficiency presented with atrophic papules and plaques on the trunk and extremities. What is your diagnosis?
This survey study collaborates with patients with dermatofibrosarcoma protuberans through social media to evaluate sources of diagnostic delay, risk of recurrence, and flat presentation of dermatofibrosarcoma protuberans.
A 71-year-old healthy woman has an enlarging, immobile, painless mass in her right gluteal area, with no neurovascular deficits; computed tomography reveals an 11-cm heterogeneous lipomatous tumor involving the right gluteal musculature. What is the diagnosis and what would you do next?
This case study describes a man in his 60s who presented with a 2-year history of gradual-onset right facial weakness leading to paralysis.
An African American man with a history of bipolar disorder presented to the emergency department with an enlarging right-sided tongue mass that had caused mild discomfort and halitosis over the course of 1 week. What is your diagnosis?
This systematic review evaluates the use of imatinib to treat locally advanced or metastatic dermatofibrosarcoma protuberans.
This case report describes a man in his 50s with a hemorrhagic nodule on his left lower cheek that developed at the site of an abrasion from a motor vehicle crash.
This case report describes orbital apex syndrome in a young man with histiocytic sarcoma.
This case study documents osteosarcoma in 240-million-year-old stem-turtle, which suggests that cancer is not a modern physiological defect.
This narrative review discusses current understanding of alveolar soft-part sarcomas with a focus on new findings and treatments.
This population-based study describes the incidence, latency period, and outcomes of radiotherapy-associated angiosarcoma among patients with breast cancer from the Netherlands Cancer Registry.
This study examines the use of next-generation sequencing for identification of potentially actionable alterations in patients with soft-tissue sarcoma.
This observational study examines the activity of anthracycline-based regimens, gemcitabine-based regimens, and pazopanib in patients with advanced epithelioid sarcoma.
This Viewpoint argues in favor of using neoadjuvant chemotherapy for the treatment of localized high-risk soft-tissue sarcoma of the extremities and trunk.
This Viewpoint argues against using neoadjuvant chemotherapy for the treatment of localized high-risk soft-tissue sarcoma of the extremities and trunk.
This case study compares diagnosis codes with pathology reports for patients diagnosed with sarcoma to assess the accuracy of disease coding at a health care center.
This study investigates the role of facility and system factors associated with survival in pediatric patients with head and neck sarcomas.
This randomized clinical trial examines whether the previously reported improvement in local progression-free survival by adding regional hyperthermia to neoadjuvant chemotherapy vs chemotherapy alone translates into improved survival in patients with soft tissue sarcoma.
A young boy presented with left facial and eye pain with intermittent diplopia on upward and lateral gaze; imaging showed a well-circumscribed posterior-medial extraconal mass extending into the orbital apex with dorsal extension into the left cavernous sinus. What is your diagnosis?
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