Explore the latest in sarcomas, including recent advances in classification, diagnosis, and medical and surgical management.
This essay describes the author’s experience in interacting with a patient diagnosed with a serious illness and how focusing on the patient’s interests and making them happy was an example of a low-tech, high-touch intervention.
An patient with a history of bullous pemphigoid treated with oral prednisolone presented with multiple round, dark brown to violaceous-colored firm nodules on the right leg and 2 nodular masses with hemorrhagic crusts on the right foot. Complete blood cell count and creatinine and liver function test results were normal, and results of HIV antibody testing were negative. What is the diagnosis and what would you do next?
This cohort study examines the outcomes observed after guideline-based 5- and 10-year follow-up in patients with gastrointestinal stromal tumor at low risk of recurrence following surgery.
This nonrandomized controlled trial of patients with advanced soft tissue sarcoma analyzed the immunomodulatory effects of intratumoral glycopyranosyl lipid A in stable-emulsion formulation with concurrent radiotherapy.
This case report describes a novel gene fusion of PAX3::INO80D in a biphenotypic sinonasal carcinoma in a woman in her 40s.
This nonrandomized clinical trial investigates the safety and effectiveness of trabectedin with radiotherapy in patients with myxoid liposarcoma.
This ancillary analysis of 2 randomized clinical trials of patients receiving neoadjuvant chemoradiotherapy or preoperative image-guided radiotherapy examines the prognostic significance of pathologic complete response on survival outcomes in patients with soft tissue sarcoma receiving neoadjuvant chemoradiotherapy.
This case report describes a large, purpuric plaque involving most of the right face with associated periorbital swelling but without ulceration.
A man in his 50s with a history of mycosis fungoides presents with bleeding wounds and nodules on the bilateral hips and forearms. What is your diagnosis?
This case report describes a man in his 60s who was referred to the department of dermatology for further evaluation of a lesion on the nose.
This case report describes a man with untreated HIV infection who presented with Kaposi sarcoma caruncular lesions that resolved completely with medical treatment.
This phase 2 nonrandomized clinical trial examines the association of cabazitaxel treatment for patients with advanced dedifferentiated liposarcoma with progression-free survival.
This case report describes a man in his 70s who presented with a bilobed, cylindrical mucosal mass that had been expelled from his mouth after an episode of nausea and violent vomiting.
This case report describes a Mediterranean HIV-negative man in his 60s with hypertension, osteoporosis, a history of flaccid paralysis after polio syndrome, and a 4-year history of progressive development of purplish, reddish cutaneous plaques and nodules limited to the lower limbs.
An adolescent girl presented with an asymptomatic slightly reddish verrucous plaque on the right temple; the skin lesion was nail sized when first noticed 1½ years ago, then gradually developed over the previous 8 months. What is your diagnosis?
A 32-year-old woman with fever, flulike symptoms, and altered mental status developed sudden-onset blurry vision in her right eye. Following intravenous antibiotics and antivirals, laboratory and imaging results were negative and her mental status improved but blurry vision persisted in the right eye. What would you do next?
This case report describes a diagnosis of orbital embryonal rhabdomyosarcoma in a man aged 22 years who presented with eyelid ptosis and diplopia.
This randomized clinical trial investigates whether carotuximab plus pazopanib improves progression-free survival vs pazopanib alone in adult patients with advanced angiosarcoma.
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