Explore the latest in sarcomas, including recent advances in classification, diagnosis, and medical and surgical management.
This case report describes orbital apex syndrome in a young man with histiocytic sarcoma.
This narrative review discusses current understanding of alveolar soft-part sarcomas with a focus on new findings and treatments.
This study examines the use of next-generation sequencing for identification of potentially actionable alterations in patients with soft-tissue sarcoma.
This observational study examines the activity of anthracycline-based regimens, gemcitabine-based regimens, and pazopanib in patients with advanced epithelioid sarcoma.
This Viewpoint argues in favor of using neoadjuvant chemotherapy for the treatment of localized high-risk soft-tissue sarcoma of the extremities and trunk.
This Viewpoint argues against using neoadjuvant chemotherapy for the treatment of localized high-risk soft-tissue sarcoma of the extremities and trunk.
This case study compares diagnosis codes with pathology reports for patients diagnosed with sarcoma to assess the accuracy of disease coding at a health care center.
This study investigates the role of facility and system factors associated with survival in pediatric patients with head and neck sarcomas.
This randomized clinical trial examines whether the previously reported improvement in local progression-free survival by adding regional hyperthermia to neoadjuvant chemotherapy vs chemotherapy alone translates into improved survival in patients with soft tissue sarcoma.
A young boy presented with left facial and eye pain with intermittent diplopia on upward and lateral gaze; imaging showed a well-circumscribed posterior-medial extraconal mass extending into the orbital apex with dorsal extension into the left cavernous sinus. What is your diagnosis?
A man in his 20s presented with a 2-month history of vague right upper quadrant abdominal pain, 5-kg weight loss, loss of appetite, and increasing abdominal distension. What is your diagnosis?
This case report describes a patient with human herpesvirus 8–associated inflammatory cytokine syndrome.
This clinical trial of pembrolizumab in combination with metronomic cyclophosphamide assesses the efficacy and safety of PD-1 targeting in combination with metronomic chemotherapy in sarcomas.
A woman in her 30s presented with a palpable, nontender, firm mass in the neck. She had a medical history of high-grade osteosarcoma with areas of leimyosarcoma of the tibia. What is your diagnosis?
A 6-year-old girl presented to the ophthalmology emergency service with 4 days of double vision associated with headache and fever. She had a history of upper respiratory tract infection with nasal congestion and discharge being treated with oral antibiotics. What would you do next?
A woman in her 80s presented with a 2-week history of an enlarging left parietal scalp mass that continued to enlarge. She subsequently developed progressive generalized weakness, slowed speech, and focal right-handed weakness. What is your diagnosis?
This case report describes the use of topical immunotherapy with diphencyprone to treat painful nodular acral recurrence of Kaposi sarcoma.
A man had worsening abdominal discomfort and a large recurrent umbilical hernia, early satiety but no nausea or vomiting, night sweats, and weight loss; examination revealed an umbilical hernia, palpable abdominal mass, and lower extremity edema. What is your diagnosis?
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