Explore the latest in soft-tissue tumors, including recent advances in classification, diagnosis, and medical and surgical management.
This nonrandomized controlled trial reports the oncological outcomes of the deintensification (from 50 Gy to 36 Gy) of a preoperative radiotherapy regimen for adults with myxoid liposarcoma.
This nonrandomized clinical trial evaluates the use of doxorubicin and pembrolizumab in patients with metastatic/unresectable anthracycline-naive sarcoma.
This cohort study compares the risk of secondary sarcoma among patients treated with combinations of surgery, radiation, and chemotherapy with patients treated with surgery alone and with the general population.
This cross-sectional study evaluates whether socioeconomic status, insurance status, or race/ethnicity are associated with the presence of metastases at the time of diagnosis of sarcoma.
This case report describes spinal cord infarction in a middle-aged man diagnosed with cardiac myxoma.
This case report describes a diffuse retinal cavernous hemangioma.
This randomized trial compares the effect of doxorubicin plus olaratumab vs doxorubicin plus placebo on overall survival in patients with advanced/metastatic soft tissue sarcoma and leiomyosarcoma.
A middle-aged woman presented with a tender, pruritic, 4-cm erythematous patch on the forehead that enlarged over the course of 6 weeks. What is your diagnosis?
This nonrandomized phase 1/2 clinical trial evaluates the use of trabectedin in combination with low-dose radiotherapy for treating metastatic soft-tissue sarcomas in adult patients.
This phase 2 clinical trial examines whether talimogene laherparepvec in combination with pembrolizumab is associated with increased tumor-infiltrating lymphocyte infiltration and programmed death-ligand 1 expression, and thus with increased antitumor activity in patients with locally advanced or metastatic sarcoma.
This Clinical Challenge describes an exceedingly rare cause for pain in the right nostril of a 31-year-old woman.
A woman in her 40s presented with a 10-year history of progressive skin thickening and subcutaneous enlargement of the right side of her nose and right cheek. What is your diagnosis?
This case report describes a patient in their 30s who presented with sudden onset of 3 generalized tonic-clonic seizures, double vision, and several days of headache, and was diagnosed with a skull base and orbital solitary plasmacytoma.
This cross-sectional study characterizes secondary genomic alterations in patients with epithelioid hemangioendothelioma and their association with clinical outcomes.
This case report describes a 42-year-old man who presented with isolated racemose angioma.
This case report describes a patient with amelanotic volar melanoma manifesting with some dermoscopic similarities to volar angioma
This case report describes a parent and child with von Hippel–Lindau disease and unusual complications.
This medical record review identifies factors and diagnostic errors that contribute to the initial misdiagnosis of optic nerve sheath meningiomas.
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