Explore the latest in leukemias, including recent advances in management of acute and chronic lymphocytic and myeloid leukemias.
This case report describes a recurrence of acute lymphoblastic leukemia manifesting as heterochromia and patchy diffuse iris infiltration with an amelanotic tumor in the right eye.
This noninferiority trial examines whether all-trans retinoic acid and arsenic trioxide therapy without maintenance chemotherapy is safe and noninferior to a historically used treatment in maintaining event-free survival among pediatric patients with newly diagnosed acute promyelocytic leukemia.
A 59-year-old man presented with progressive hoarseness and dyspnea 15 months after an allogeneic stem cell transplant for treatment of acute myeloid leukemia. What is your diagnosis?
This cohort study uses quantitative and qualitative methods to compare medical and quality of life outcomes among pediatric patients with acute myeloid leukemia receiving inpatient vs outpatient neutropenia management.
A patient with chronic myelogenous leukemia presented with blurry vision and peripapillary intraretinal and preretinal hemorrhages obscuring the optic disc margins of both eyes. What would you do next?
This cohort study examines whether focal deletions within the λ variable chain region in chromosome 22q11.22 were associated with patients with B-ALL with IKZF1 alterations with the highest risk of relapse and/or death.
This nonrandomized phase 2 trial examines remission after combination therapy with ibrutinib and venetoclax in treatment-naive patients with chronic lymphocytic leukemia.
This cohort study examines the association of a celebrity’s public disclosure of an acute lymphocytic leukemia diagnosis and trends in bone marrow donor registration in Japan.
This systematic review and meta-analysis examines the relative risk of hepatotoxicity of new-generation BCR-ABL fusion oncoprotein tyrosine kinase inhibitors (TKIs) vs imatinib among patients with chronic myeloid leukemia.
This registry-based cohort study investigates postremission treatment choices and outcomes based on dynamic measurable residual disease in adults with intermediate-risk acute myeloid leukemia (AML).
This case study presents the electrocardiographic findings in a man in his 50s with a history of acute promyelocytic leukemia treated with arsenic trioxide who was hospitalized with recurrent loss of consciousness.
This cross-sectional study assesses whether health literacy, contextual factors, or sociodemographic characteristics are associated with perception of voluntariness among parents who consent for their child’s participation in a leukemia therapeutic clinical trial.
An elderly man with a history of Philadelphia chromosome–positive acute lymphocytic leukemia, diabetes, and dementia presented with decreased visual acuity and hypopyon in his right eye. What would you do next?
An adolescent boy with acute leukemia of ambiguous lineage developed tender, erythematous plaques and nodules during treatment with chemotherapy. What is your diagnosis?
A 64-year-old woman presented with 27 mm of bilateral proptosis, conjunctival injection, lower eyelid retraction, and free extraocular movements. An orbital computed tomography scan revealed marked enlargement of every extraocular muscle. What would you do next?
This randomized clinical trial assesses the effect of integrated palliative and oncology care on patient-reported and end-of-life outcomes in patients with acute myeloid leukemia.
This nonrandomized clinical trial evaluates molecular recurrence and patient-reported outcomes after tyrosine kinase inhibitor discontinuation in US patients with chronic myeloid leukemia.
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