Explore the latest in opioid use disorders from The JAMA Network, including recent advances in opioid rehabilitation programs, treatments, and public health interventions.
This medical record review study compares the clinical characteristics of endogenous endophthalmitis in patients with and without injection drug use.
This case series examines patient use of an opioid-based drug after rhinoplasty to establish an optimal pain management regimen that also mitigates the misuse or diversion of physician-prescribed opioid medications.
A comprehensive urine drug screen for a 50-year-old woman taking daily methadone, immediate-release morphine, gabapentin, duloxetine, and celecoxib for pain was positive for methadone and morphine but also codeine and hydromorphone. How do you interpret the results?
This randomized clinical trial compares the efficacy of 4 oral combination analgesics among adult patients treated for moderate to severe acute extremity pain at 2 urban emergency departments in the United States.
This observational cohort study determines the opioid prescribing patterns among ophthalmologists and elucidates ophthalmologists’ role in the prescription opioid abuse epidemic.
This Viewpoint discusses the president’s recent declaration of a public health emergency in response to the opioid crisis in the United States.
In this Viewpoint, former CDC Director Tom Frieden outlines 10 steps the federal government should take to prevent opioid addiction among nonusers and treat addiction and prevent overdoses among current users.
This systematic review and meta-analysis outlines the evidence for nonpharmacological interventions for postoperative pain management after total knee arthroplasty.
This randomized clinical trial compares the effectiveness of extended-release naltrexone with that of buprenorphine-naloxone in maintaining short-term abstinence from heroin and other illicit substances.
In this Viewpoint, authors from the US CDC’s National Center for Injury Prevention and Control discuss infrastructure investments, legal changes, and clinical and public health strategies for reducing overdose deaths among opioid users.
This randomized clinical trial examines whether collaborative care for patients with opioid and/or alcohol use disorders improves the delivery of evidence-based treatments and increases self-reported abstinence compared with usual primary care.
This Viewpoint describes an organization created to share stories and experiences of medical professionals.
This multicenter cohort study examines the procedural sedation practices, adverse events, and risk factors for children undergoing painful procedures in Canadian emergency departments.
This study of insurance claims data investigates whether the 2012 issuance of a black box warning against codeine use following tonsillectomy was followed by changes in prescribing patterns.