Explore the latest in antibiotic use, overuse, resistance, and stewardship, including evolving antimicrobial susceptibility patterns and more.
This case series study assesses risk after the identification of an unexpected, severe, and lethal hospital-acquired infection caused by carbapenemase-producing Pseudomonas aeruginosa in a carbapenemase-low endemic setting in the Netherlands.
This analysis uses hospital billing databases of inpatient discharges to compare antibiotic prescribing for community-acquired pneumonia by hospital type.
This cohort study uses data from the Premier Inpatient Database to assess outcomes associated with the addition of antibiotic treatment in patients hospitalized for asthma exacerbation treated with corticosteroids who had no other indication for antibiotic therapy.
This cohort study compares the 30-day mortality among hospitalized patients with Enterobacteriaceae bacteremia treated with oral step-down therapy vs intravenous therapy.
This repeated cross-sectional analysis of antibiotic prescribing by dermatologists characterizes the use of antibiotics in dermatology, including changes over time, from 2008 to 2016.
This JAMA Patient Page describes evaluation for and diagnosis of penicillin allergy.
This narrative review summarizes the epidemiology of penicillin allergy and the clinical consequences of misattributing adverse drug events to β-lactam allergy, including development of antimicrobial resistance and adverse events associated with alternative antibiotics, and proposes an algorithm to facilitate evaluation of true penicillin allergy.
This Viewpoint summarizes recommendations from the Agency for Healthcare Research and Quality for improving antibiotic use and safety that encourages clinicians to ask if antibiotics are necessary, and to use testing and deliberate judgment to decide which ones, for how long, and if coverage can be narrowed or the drugs stopped altogether.
This analysis of surveillance data from 10 US states describes incidence, characteristics, antimicrobial resistances, and serotype distribution of early-onset and late-onset group B Streptococcus disease in infants younger than 90 days.
This cohort study describes the rates of major surgical site infection for patients undergoing cochlear implantation who receive prolonged antibiotic treatment compared with those who receive a single perioperative dose of antibiotic prophylaxis.
This double-blind, randomized clinical noninferiority trial evaluates whether placebo treatment is significantly inferior to 3 days of oral amoxicillin treatment in HIV-uninfected children aged 2 to 59 months with nonsevere fast-breathing pneumonia in a malaria-endemic region of Malawi, Africa.
This systematic review and meta-analysis compares the pooled results of randomized clinical trials that examined the effect of antibiotic preventive therapy on postoperative complications in patients undergoing rhinoplasty.
This cohort study evaluates the use of and prescribing patterns for antimicrobial medications in patients who underwent urologic procedures at Veterans Health Administration hospitals.
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