Explore the latest in antibiotic use, overuse, resistance, and stewardship, including evolving antimicrobial susceptibility patterns and more.
This randomized clinical trial compares antibiotic use among adult patients in Pakistan receiving bismuth subsalicylate vs placebo for diarrhea.
This multicenter nonrandomized clinical trial with crossover design study determines the feasibility and results of implementing 2 core stewardship intervention strategies, preauthorization and postprescription audit and review, in community hospitals.
This population-based cohort study examines the sex-based variations in burdensome interventions (care transitions, invasive procedures, and use of physical restraints) and antibiotic therapy at the very end of life among nursing home residents with advanced dementia in Ontario, Canada.
This Medical Letter review summarizes indications, dosing, and cost of Nuzyra, a semisynthetic tetracycline derivative, for once-daily intravenous and oral treatment of community-acquired bacterial pneumonia and acute bacterial skin and skin structure infections in adults
This randomized clinical trial evaluates the effectiveness of a bundle of evidence-supported treatments under conditions of routine care in a representative population hospitalized for community-acquired pneumonia.
This Clinical Guideline Synopsis reviews the Tokyo Guidelines 2018 on antimicrobial therapy for acute cholangitis and cholecystitis.
This JAMA Patient Page describes the utility of and procedures for administering intravenous antibiotics at home.
This national cohort study assesses the association of type and duration of prophylaxis with surgical site infection, acute kidney injury, and Clostridium difficile infection.
This time series study evaluates whether increasing the threshold for identifying uropathogens is associated with a decrease in antimicrobial treatment.
This Patient Page describes how and why children may be evaluated for penicillin allergy.
This nested case-control study uses a large primary care population database in the United Kingdom to analyze the relative and absolute risk estimates of peripheral neuropathy among adults issued prescriptions for oral fluoroquinolone or amoxicillin-clavulanate antibiotics.
This medical record review investigates whether use of topical clindamycin and/or oral tetracyclines during management of epidermal growth factor receptor (EGFR) inhibitor–related papulopustular eruption is associated with antibiotic-resistant bacterial infection.
This systematic review and meta-analysis reviews 21 prospective trials to evaluate short-course antibiotic prophylaxis vs extended-course antibiotic prophylaxis with regard to rates of surgical site infection after ear, nose, throat, and oral and maxillofacial surgery.
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