Explore the latest in antibiotic use, overuse, resistance, and stewardship, including evolving antimicrobial susceptibility patterns and more.
This JAMA Insights discusses the use of antibiotics for sexually transmitted infection prevention.
This cohort study compares the rate of treatment failure and adverse events associated with amoxicillin-clavulanate vs amoxicillin in children newly diagnosed with acute sinusitis in an outpatient setting.
This Viewpoint discusses whether routine vaccination is safe for children with MT-RNR1 gene variants that predispose to aminoglycoside-induced hearing loss.
This quality improvement study evaluates whether pediatric intensive care units sustained reduced blood culture rates after participation in the Bright STAR collaborative from 2017 to 2020.
This quality improvement study aims to determine whether diagnostic stewardship (avoiding unnecessary urine cultures) or antibiotic stewardship (reducing unnecessary antibiotic treatment after an unnecessary culture) is associated with better outcomes in reducing antibiotic use for asymptomatic bacteriuria.
This randomized clinical trial aims to determine whether a direct oral penicillin challenge is noninferior to the standard of care of penicillin skin testing followed by an oral challenge in patients with a low-risk penicillin allergy.
This study describes trial participation and compares clinical and patient-reported outcomes among Spanish-speaking and English-speaking participants randomized to antibiotics.
This combination cohort and case-crossover study evaluates the association between fluoroquinolone use and hospitalization with aortic aneurysm or aortic dissection.
This cohort study examines the factors involved and times to diagnosis and treatment initiation in patients with head and neck cancer at the time of presentation with symptoms.
This cohort study uses registry data to report the long-term outcomes of patients who participated in randomized clinical trials of antibiotics vs surgery in Sweden in the 1990s.
This cohort study evaluated the diagnostic accuracy of PEN-FAST as a clinical decision-making tool to enhance penicillin allergy evaluation.
This consensus statement provides clinical guidelines for the diagnosis and management of adult bacterial infective endocarditis.
This cross-sectional study assesses the characteristics of patients and physicians associated with antibiotic prescription for COVID-19.
This randomized clinical trial compares the effect of amoxicillin and clavulanate vs placebo on symptom burden in children diagnosed with acute sinusitis.
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