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    Hepatitis B

    Explore the latest in hepatitis B, including recent advances in diagnosis and antiviral treatment, prevention of complications, and more.

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    • Hepatitis D: A Review
      JAMA
      Review
      November 9, 2023

      This review summarizes current evidence regarding diagnosis and treatment of hepatitis D virus.

      Hepatobiliary Disease Gastroenterology and Hepatology Viral Hepatitis Infectious Diseases
      Full Text | pdf link PDF | CME & MOC is active quiz
    • Tenofovir vs Entecavir Among Patients With HBV-Related HCC After Resection
      JAMA Network Open
      Research
      October 31, 2023

      This cohort study explores differences in recurrence-free survival and overall survival associated with tenofovir disoproxil vs entecavir after liver resection with curative intent in patients with hepatocellular cancer (HCC) related to hepatitis B virus (HBV).

      Gastroenterology and Hepatology Infectious Diseases Oncology Surgery Surgical Oncology
      Full Text | pdf link PDF open access
    • Assessment of Prior Infection With Hepatitis B Virus and Fecundability in Couples Planning Pregnancy
      JAMA Network Open
      Research
      August 31, 2023

      This cohort study investigates the association of hepatitis B virus infection and time to pregnancy in couples planning pregnancy and explores whether this association varies by gravidity, health status, or lifestyle.

      Obstetrics and Gynecology Nutrition, Obesity, Exercise Viral Hepatitis Hepatobiliary Disease Gastroenterology and Hepatology
      Full Text | pdf link PDF open access
    • Maternal Hepatitis B Virus Infection and Pregnancy Outcomes of Freeze-Thaw Embryo Transfer
      JAMA Network Open
      Research
      July 14, 2023

      This cohort study assesses the association of maternal hepatitis B virus (HBV) serostatus with pregnancy outcomes in women undergoing freeze-thaw embryo transfer (FET).

      Neonatology Pediatrics Pregnancy Obstetrics Women's Health
      Full Text | pdf link PDF open access
    • Daily Low-Volume Paracentesis and Clinical Complications in Patients With Refractory Ascites
      JAMA Network Open
      Research
      July 6, 2023

      This cohort study examines the association of daily drainage volume and the incidence of complications, such as hyponatremia or acute kidney injury, in patients with cirrhosis and refractory ascites treated with devices.

      Gastroenterology and Hepatology Infectious Diseases Oncology Viral Hepatitis Hepatitis C
      Full Text | pdf link PDF open access
    • Overcome Health Inequities to Eliminate Viral Hepatitis
      JAMA
      Opinion
      May 16, 2023

      This Viewpoint outlines the progress made toward eliminating hepatitis B and C but emphasizes the work that remains to prioritize diagnosis and treatment of populations disproportionately affected by viral hepatitis, including ensuring that there are systems in place to treat those infected and care for those at risk.

      Hepatobiliary Disease Gastroenterology and Hepatology Health Inequities Equity, Diversity, and Inclusion Infectious Diseases
      Full Text | pdf link PDF
    • Universal Adult Hepatitis B Screening and Vaccination as the Path to Elimination
      JAMA
      Opinion
      May 16, 2023

      This Viewpoint describes new recommendations from the CDC regarding universal screening of adults for hepatitis B virus infection.

      Infectious Diseases Vaccination Viral Hepatitis Hepatobiliary Disease Gastroenterology and Hepatology
      Full Text | pdf link PDF
    • Maternal Preconception Hepatitis B Virus Infection and Risk of Congenital Heart Diseases in Offspring Among Chinese Women Aged 20 to 49 Years
      JAMA Pediatrics
      Research
      May 1, 2023

      This cohort study explores the association of maternal preconception hepatitis B virus infection with congenital heart diseases in offspring.

      Global Health Infectious Diseases Viral Hepatitis Hepatobiliary Disease Antenatal Exposures and Child Outcomes
      Full Text | pdf link PDF
    • Estimated Use of Prescription Medications Among Individuals Incarcerated in Jails and State Prisons in the US
      JAMA Health Forum
      Research
      April 14, 2023

      This cross-sectional study evaluates treatment with prescription medications in jails and state prisons relative to noncorrectional settings in the US.

      Health Policy Diabetes and Endocrinology Diabetes Psychiatry and Behavioral Health Hypertension
      Full Text | pdf link PDF open access
    • Examining the Hepatitis B Care Cascade Through an Equity Lens
      JAMA Network Open
      Opinion
      April 10, 2023
      Gastroenterology and Hepatology Health Policy Health Inequities Health Disparities Infectious Diseases
      Full Text | pdf link PDF open access
    • Racial Disparities in Treatment Initiation and Outcomes of Chronic Hepatitis B Virus Infection in North America
      JAMA Network Open
      Research
      April 10, 2023

      This cohort study examines treatment for chronic hepatitis B among a racially diverse group of individuals in North America.

      Gastroenterology and Hepatology Health Policy Health Inequities Health Disparities Infectious Diseases
      Full Text | pdf link PDF open access
    • Factors Associated With Quality Care Among Adults With Rheumatoid Arthritis
      JAMA Network Open
      Research
      December 12, 2022

      This cohort study assesses the prevalence of meeting successive markers of quality care for individuals with rheumatoid arthritis and characteristics associated with meeting these markers.

      Rheumatology Rheumatoid Arthritis Health Care Quality Gastroenterology and Hepatology Infectious Diseases
      Full Text | pdf link PDF open access
    • Association of Heavy Alcohol Intake and ALDH2 rs671 Polymorphism With Hepatocellular Carcinoma and Mortality in Patients With Hepatitis B Virus–Related Cirrhosis
      JAMA Network Open
      Research
      July 25, 2022

      This cohort study investigates the association of heavy alcohol intake, aldehyde dehydrogenase 2 gene (ALDH2) rs671 polymorphism, and hepatitis B virus infection with hepatocellular carcinoma development and mortality in patients with cirrhosis.

      Gastroenterology and Hepatology Hepatobiliary Disease Viral Hepatitis Infectious Diseases Genetics and Genomics
      Full Text | pdf link PDF open access
    • Association of Nationwide Hepatitis B Vaccination and Antiviral Therapy Programs With End-Stage Liver Disease Burden in Taiwan
      JAMA Network Open
      Research
      July 18, 2022

      This cohort study examines the associations of nationwide hepatitis B vaccination and antiviral therapy programs implemented in Taiwan with the burden of end-stage liver disease by age, period, and cohort.

      Public Health Gastroenterology and Hepatology Health Policy Hepatobiliary Disease Infectious Diseases
      Full Text | pdf link PDF open access
    • Risk of Hepatocellular Carcinoma With Tenofovir vs Entecavir Treatment for Chronic Hepatitis B Virus: A Reconstructed Individual Patient Data Meta-analysis
      JAMA Network Open
      Research
      June 29, 2022

      This meta-analysis reconstructs individual participant data from high-quality, propensity score–matched cohort studies and provides more accurate and precise estimates of hepatocellular carcinoma (HCC) risk among patients with chronic hepatitis B virus.

      Gastroenterology and Hepatology Pharmacy and Clinical Pharmacology Clinical Pharmacy and Pharmacology Hepatobiliary Disease Gastroenterology
      Full Text | pdf link PDF open access
    • Regional Differences in Mortality Rates and Characteristics of Decedents With Hepatitis B Listed as a Cause of Death, United States, 2000-2019
      JAMA Network Open
      Research
      June 28, 2022

      This cross-sectional study assesses characteristics of US decedents with hepatitis B–listed deaths during 2010 to 2019 and compares rates with 2000 to 2009.

      Public Health Gastroenterology and Hepatology Infectious Diseases Viral Hepatitis Hepatobiliary Disease
      Full Text | pdf link PDF open access
    • A Patient With Jaundice and Malaise
      JAMA
      Case Report
      June 28, 2022

      A woman with a history of intravenous heroin use and chronic inactive hepatitis B virus infection had sudden onset of painless jaundice and malaise. Vital signs, mentation, and physical examination were normal except for scleral icterus; she reported no history of travel outside the US and no raw meat ingestion; aminotransferase and bilirubin levels were newly elevated, but she had no acute hepatitis A or C virus infection. What is the diagnosis and what would you do next?

      Infectious Diseases Clinical Challenge Hepatobiliary Disease Gastroenterology and Hepatology Viral Hepatitis
      Full Text | pdf link PDF | CME & MOC is active quiz
    • Age Range Is Expanded for Universal Hepatitis B Vaccination
      JAMA
      News
      May 10, 2022
      Vaccination Viral Hepatitis Hepatobiliary Disease Gastroenterology and Hepatology Infectious Diseases
      Full Text | pdf link PDF
    • Association Between 2-Dose vs 3-Dose Hepatitis B Vaccine and Acute Myocardial Infarction
      JAMA
      Research
      April 5, 2022

      This large prospective cohort study compares the rates of acute myocardial infarction between recipients of a 2-dose hepatitis B vaccine and recipients of a 3-dose hepatitis B vaccine.

      Vaccination Viral Hepatitis Ischemic Heart Disease Acute Coronary Syndromes Cardiology
      Full Text | pdf link PDF free
    • Trends in Pricing and Out-of-Pocket Spending on Entecavir Among Commercially Insured Patients, 2014-2018
      JAMA Network Open
      Research
      January 21, 2022

      This cross-sectional study of health claims from patients with private insurance examines trends in the cost of entecavir prescribed for chronic hepatitis B treatment.

      Infectious Diseases Viral Hepatitis Hepatobiliary Disease Health Care Economics, Insurance, Payment Gastroenterology and Hepatology
      Full Text | pdf link PDF open access
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