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    Sexual Dysfunctions

    Explore the latest in sexual dysfunctions, including erectile dysfunction, hypoactive sexual desire, orgasmic disorders, and more.

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    • Genitourinary Syndrome of Menopause and the False Promise of Vaginal Laser Therapy
      JAMA Network Open
      Opinion
      February 10, 2023
      Obstetrics and Gynecology Breast Cancer Oncology Cancer Survivorship Gynecology
      Full Text | pdf link PDF open access
    • Effect of Fractional Carbon Dioxide vs Sham Laser on Sexual Function in Survivors of Breast Cancer Receiving Aromatase Inhibitors for Genitourinary Syndrome of Menopause: The LIGHT Randomized Clinical Trial
      JAMA Network Open
      Research
      February 10, 2023

      This randomized clinical trial assesses the safety and efficacy of carbon dioxide (CO2) vs sham vaginal laser treatment after 6 months of follow-up in survivors of breast cancer receiving aromatase inhibitors with genitourinary syndrome of menopause.

      Obstetrics and Gynecology Breast Cancer Oncology Gynecology Women's Health
      Full Text | pdf link PDF open access
    • Effects of Kisspeptin on Sexual Brain Processing and Penile Tumescence in Men With Hypoactive Sexual Desire Disorder: A Randomized Clinical Trial
      JAMA Network Open
      Research
      February 3, 2023

      This randomized clinical trial investigates the physiological, behavioral, neural, and hormonal effects of kisspeptin administration in men with hypoactive sexual desire disorder.

      Diabetes and Endocrinology Endocrinology Genetics and Genomics Urology Psychiatry and Behavioral Health
      Full Text | pdf link PDF open access
    • Knowledge, Attitudes, and Practice Patterns Relating to Sexual Dysfunction Among Urologists and Andrologists in China
      JAMA Network Open
      Research
      January 12, 2023

      This survey study explores the knowledge, attitudes, and practice patterns related to sexual dysfunction among urologists and andrologists in China.

      Urology Psychiatry and Behavioral Health Global Health
      Full Text | pdf link PDF open access
    • Effects of Kisspeptin Administration in Women With Hypoactive Sexual Desire Disorder: A Randomized Clinical Trial
      JAMA Network Open
      Research
      October 26, 2022

      This randomized clinical trial of 32 premenopausal women with hypoactive sexual desire disorder examines the effectiveness of a kisspeptin infusion in enhancing sexual and attraction brain processing.

      Diabetes and Endocrinology Clinical Pharmacy and Pharmacology Endocrinology Drug Development Pharmacy and Clinical Pharmacology
      Full Text | pdf link PDF open access
    • Dyspareunia in Women
      JAMA
      Review
      May 10, 2022

      This JAMA Insights in the Women’s Health series describes the identification and management of dyspareunia to help address sexual pain; successful treatment can have benefits for both physical and mental health.

      Psychiatry and Behavioral Health Gynecology Women's Health Obstetrics and Gynecology
      Full Text | pdf link PDF | CME & MOC is active quiz
    • A Randomized Clinical Trial in Patients With a Pedophilic Disorder: A Milestone
      JAMA Psychiatry
      Opinion
      September 1, 2020
      Psychiatry and Behavioral Health
      Full Text | pdf link PDF
    • Effect of Gonadotropin-Releasing Hormone Antagonist on Risk of Committing Child Sexual Abuse in Men With Pedophilic Disorder: A Randomized Clinical Trial
      JAMA Psychiatry
      Research
      September 1, 2020

      This randomized clinical trial evaluates the immediate efficacy of testosterone-suppressing medication in reducing the risk scores in 5 domains of child sexual abuse among men with pedophilic disorder.

      Psychiatry and Behavioral Health
      Full Text | pdf link PDF open access
    • Prostate Cancer Drug Degarelix Rapidly Treats Pedophilic Disorder
      JAMA
      News
      June 23, 2020
      Psychiatry and Behavioral Health
      Full Text | pdf link PDF
    • Possible Reasons US Adults Are Not Having Sex as Much as They Used To
      JAMA Network Open
      Opinion
      June 12, 2020
      Public Health Infectious Diseases Sexually Transmitted Infections Pediatrics Adolescent Medicine
      Full Text | pdf link PDF open access
    • Trends in Frequency of Sexual Activity and Number of Sexual Partners Among Adults Aged 18 to 44 Years in the US, 2000-2018
      JAMA Network Open
      Research
      June 12, 2020

      This survey study of adults aged 18 to 44 years examines trends in reported frequency of sexual activity and number of sexual partners and the association between measures of sexual activity and sociodemographic variables.

      Public Health Adolescent Medicine Infectious Diseases Lifestyle Behaviors Pediatrics
      Full Text | pdf link PDF open access
    • Prevalence of Distress Associated With Difficulty Controlling Sexual Urges, Feelings, and Behaviors in the United States
      JAMA Network Open
      Research
      November 9, 2018

      This survey study investigates the prevalence of distress and impairment associated with difficulty controlling one’s sexual feelings, urges, and behaviors among US men and women.

      Psychiatry and Behavioral Health LGBTQIA Medicine
      Full Text | pdf link PDF open access
    • Association of Continuous Positive Airway Pressure Treatment With Sexual Quality of Life in Patients With Sleep Apnea: Follow-up Study of a Randomized Clinical Trial
      JAMA Otolaryngology–Head & Neck Surgery
      Research
      July 1, 2018

      This cohort study evaluates the association of sexual quality of life in patients with newly diagnosed obstructive sleep apnea who used continuous positive airway pressure (CPAP) for 12 months vs those who did not use CPAP.

      Critical Care Medicine Respiratory Failure and Ventilation Obstructive Sleep Apnea Pulmonary Medicine Sleep Medicine
      Full Text | pdf link PDF free
    • Prasterone (Intrarosa) for Dyspareunia
      JAMA
      Review
      October 24, 2017

      This Medical Letter review summarizes treatment options for dyspareunia, focusing on use of intravaginal prasterone for treatment of moderate to severe dyspareunia in postmenopausal women.

      Psychiatry and Behavioral Health Gynecology Women's Health Obstetrics and Gynecology
      Full Text | pdf link PDF
    • Relief for Painful Intercourse
      JAMA
      News
      January 3, 2017
      Women's Health Geriatrics
      Full Text | pdf link PDF
    • Low Testosterone in Men Should Be a Sign Rather Than a Number to Increase: A Teachable Moment
      JAMA Internal Medicine
      Opinion
      December 1, 2016

      This Teachable Moment calls attention to the need to investigate the underlying cause of low testosterone levels or symptoms of hypogonadism.

      Teachable Moment Diabetes and Endocrinology Endocrinology Genetics and Genomics Oncology
      Full Text | pdf link PDF
    • Adverse Health Events Following Intermittent and Continuous Androgen Deprivation in Patients With Metastatic Prostate Cancer
      JAMA Oncology
      Research
      April 1, 2016

      This secondary analysis of clinical trial data examines older men assigned to intermittent androgen-deprivation therapy to determine frequency of bone, endocrine, cognitive, ischemic, and thrombotic events.

      Geriatrics Oncology Prostate Cancer Urology Urologic Cancer
      Full Text | pdf link PDF free
    • Efficacy and Safety of Flibanserin for the Treatment of Hypoactive Sexual Desire Disorder in Women: A Systematic Review and Meta-analysis
      JAMA Internal Medicine
      Research
      April 1, 2016

      This systematic review and meta-analysis of randomized clinical trials assesses the efficacy and safety of flibanserin for the treatment of hypoactive sexual desire disorder in women.

      Psychiatry and Behavioral Health Gynecology Women's Health Obstetrics and Gynecology Health Care Safety
      Full Text | pdf link PDF free
    • New Drug for Sexual Desire Disorder
      JAMA
      News
      October 6, 2015
      Psychiatry and Behavioral Health
      Full Text | pdf link PDF
    • Flibanserin for Treating Low Sexual Desire in Women
      JAMA
      Patient Information
      September 22, 2015
      Clinical Pharmacy and Pharmacology Patient Information Adverse Drug Events JAMA Patient Information Psychiatry and Behavioral Health
      Full Text | pdf link PDF free
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