Explore the latest in hepatobiliary disease, including recent advances in treatment of viral hepatitis, hepatobiliary cancers, and more.
A 55-year-old man with several weeks of malaise, a 6.8-kg weight loss, a CT scan with multifocal liver masses and elevated alkaline phosphatase, ALT, and AFP levels had a heterogeneously enhancing pancreatic-tail mass on triple-phase CT. What would you do next?
This JAMA Patient Page describes recent advancements in hepatitis C treatment.
This single-arm, 2-stage, phase 2 clinical trial assesses the safety and efficacy of intravenous gemcitabine plus nanoparticle albumin-bound–paclitaxel for treatment of adults with advanced cholangiocarcinoma.
This JAMA Clinical Guidelines Synopsis summarizes the 2017 practice guidance from the American Association for the Study of Liver Diseases on diagnosis and management of nonalcoholic fatty liver disease.
This case report describes metastatic calcinosis cutis associated with selective FGFR inhibitor therapy.
This JAMA Patient Page describes the endoscopic retrograde cholangiopancreatography procedure and its purposes.
A 68-year-old man has an undetectable hepatitis C (HCV) viral load, normal liver function tests, and an elevated vibration-controlled transient elastography (VCTE) measure after 12 weeks of antiviral treatment for HCV with stage 2 fibrosis by biopsy. How do you interpret the results?
This Viewpoint discusses a “Netflix” subscription model of drug payment being investigated by Louisiana for hepatitis C (HCV) drugs, in which a statewide coalition of payers would pay subscription fees over a fixed number of years for HCV drugs to treat all state residents and for efforts by the manufacturers to enhance treatment rates through patient outreach.
This multicenter study investigates the risk factors, patterns, and outcomes of late recurrence after curative liver resection for hepatocellular carcinoma.
This study evaluates the accuracy of the Pediatric End-stage Liver Disease score in estimating 90-day pretransplant mortality among of pediatric patients on the United Network for Organ Sharing waiting list.
This Insights discusses management strategies for liver neuroendocrine tumors using the most recent therapeutic options.
This cohort study examines the association of preoperative antiviral treatment with the incidences of microvascular invasion and posthepatectomy early tumor recurrence in adult patients with hepatitis B virus–related hepatocellular carcinoma.
This JAMA Patient Page describes the symptoms, diagnosis, and treatment of gallstones and biliary colic.
This JAMA Patient Page describes the symptoms, diagnosis, and treatment of choledocholithiasis.
This cohort study uses data from the Korean National Health Insurance Service database to compare the risk of hepatocellular cancer associated with entecavir vs tenofovir disoproxil fumarate in patients receiving long-term treatment for chronic hepatitis B infection.
A 55-year-old man with a history of Childs B cirrhosis presents with a 2.5-year history of right groin pain and increased urinary frequency with difficulty voiding. What is your diagnosis?
This JAMA Patient Page describes the symptoms, diagnosis, and treatment of gallbladder cancer.
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