Explore the latest in adverse drug events, including postmarketing surveillance, risk mitigation, and the pharmacogenetics of safety.
This cohort study estimates rates of myocarditis and pericarditis after receipt of an mRNA COVID-19 vaccine among individuals in Ontario, Canada, stratified by recipients’ age and sex and by the vaccine product, schedule, and interdose interval.
This study evaluates the association between the AZD1222, BNT162b2, and mRNA-1273 vaccines and subsequent thromboembolic and thrombocytopenic events between 3 Nordic countries.
A 32-year-old woman with fever, flulike symptoms, and altered mental status developed sudden-onset blurry vision in her right eye. Following intravenous antibiotics and antivirals, laboratory and imaging results were negative and her mental status improved but blurry vision persisted in the right eye. What would you do next?
This cohort study compares outcomes of 104 patients with unresectable locally advanced non–small cell lung cancer with and without driver variations treated with the PACIFIC regimen.
This Viewpoint describes the successes and gaps in research and clinical care of Steven-Johnson syndrome and toxic epidermal necrolysis.
This case report describes the electrocardiogram findings of a patient with 1 week of progressive weakness, myalgia, dyspnea, and ptosis.
This Teachable Moment describes a man in his 70s with stage III colon cancer who presented with sensory symptoms after undergoing chemotherapy and was diagnosed with chemotherapy-induced peripheral neuropathy.
This cohort study evaluates the comparative safety and health care expenditures of inappropriate vs appropriate oral antibiotic prescriptions for common outpatient pediatric infections.
This systematic review examines the risk factors, clinical presentation, diagnostic findings, treatments, and outcomes of immune checkpoint inhibitor–induced bullous pemphigoid.
This cohort study investigates the association of montelukast treatment with adverse neuropsychiatric outcomes among patients with asthma or allergic rhinitis.
This case report describes 2 adult patients with diffuse large B-cell lymphoma who presented with small, tense blisters that appeared after receiving treatment with loncastuximab tesirine.
This cohort study with a case-crossover analytical design examines the associations between prescription stimulant use and drug-related poisonings and buprenorphine treatment retention among patients with opioid use disorder.
This cohort study assesses the outcomes of acitretin treatment for multikinase inhibitor–associated hand-foot skin reaction.
This case report describes a patient with photodistributed Stevens-Johnson syndrome and toxic epidermal necrolysis and highlights similarities to other cases reported in the literature.
This systematic review and meta-analysis of 76 randomized clinical trials examines the effects of glucagon-like peptide-1 receptor agonist use on the risk of gallbladder and biliary diseases.
This pragmatic prospective implementation trial uses a rapid genotyping platform for the m.1555A>G variant to assess whether this technology could be implemented to avoid aminoglycoside-induced ototoxicity without disrupting normal clinical practice on neonatal intensive care units.
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