Explore the latest in adverse drug events from The JAMA Network, including postmarketing surveillance, risk mitigation, and the pharmacogenetics of safety.
This case report describes the occurrence of generalized lichen nitidus following anti–PD-1 antibody treatment.
This cohort study evaluates if age influences clinical outcome and immune adverse events in patients treated by immunotherapy for `metastatic melanoma.
This case report of a woman who developed Stevens-Johnson syndrome during pregnancy describes the treatment of her newborn with the culprit drug.
This Patient Page provides information on Stevens-Johnson syndrome and toxic epidermal necrolysis and advises patients on care and treatment as well as ways to avoid recurrences.
This Viewpoint discusses the need to balance speed of approval and safety of drugs in the US Food and Drug Administration’s process of drug approval.
This Medical News article examines the use of stomach acid suppressors to treat mild gastric reflux in infants.
This population-based, case series study examines the incidence of suicide attempts during treatment with methylphenidate in patients with attention-deficit/hyperactivity disorder.
This systematic review and meta-analysis examines the responses of children and adolescents with common psychiatric disorders who receive selective serotonin reuptake inhibitors, serotonin-norepinephrine reuptake inhibitors, or placebo.
This cross-sectional analysis of trial documents submitted to regulators examines the degree to which the study purpose is explained to potential participants in randomized clinical trials of antibiotics.
A 15-year-old boy presented to a hospital with pain and purpura of his left thigh after an intramuscular injection. What is your diagnosis?
This cohort study investigates the frequency, clinical spectrum, and optimum treatment approach to neurological complications associated with anti–PD-1 inhibitor use.
This case series investigates whether low-dose naltrexone is an effective treatment for recalcitrant Hailey-Hailey disease.
This nonrandomized interventional cohort study investigates the safety and efficacy of cryolipolysis for reduction of lateral and central submental fat.
This cohort study describes the incidence of antibiotic-associated adverse drug events for adult inpatients receiving systemic antibiotic therapy.
This case series describes alemtuzumab-induced neutropenia in 2 patients with multiple sclerosis.
This study characterizes purpuric skin eruptions caused by epidermal growth factor receptor inhibitors.
This Viewpoint questions the use of anthracyclines in the treatment of gastroesophageal cancers.