Connective Tissue Disease of the Skin

This case report describes a 78-year old woman with a stage IIA BRAF wild-type melanoma on the left leg who experienced a grade 2 vitiligo, a marked skin thickening, and painful swelling of the limbs.

This nonrandomized controlled trial investigates the overall response rate associated with apremilast as an add-on therapy among patients with recalcitrant cutaneous dermatomyositis.

This Patient Page describes the symptoms, diagnosis, and treatment of sarcoidosis of the skin.

This case report describes 2 women with severe and refractory discoid lupus erythematosus that was treated with anifrolumab.

This cohort study evaluates the incidence of dermatomyositis and its trend over time in the US Department of Veterans Affairs health care system.

This descriptive case series investigates the potential association between the use of proton pump inhibitors and drug-induced lupus erythematosus in cases reported in 2 large pharmacovigilance databases.

A man in his 60s with systemic sclerosis complicated by scleroderma kidney crisis, heart failure, interstitial lung disease, sclerodactyly, and Raynaud phenomenon presented with a pruritic rash. What is your diagnosis?

This case report describes a woman in her 20s with a history of psoriasis and juvenile dermatomyositis who presented for management of worsening psoriasis at a time when her juvenile dermatomyositis had been in remission for several years.

This case report describes violaceous papules on the nasal alae and medial periorbital skin, hypopigmented indurated plaques on the bilateral upper extremities and back, and verrucous plaques on the lower extremities and back.

This case report describes ragged cuticles; flat-topped pink papules overlying the bilateral metacarpophalangeal, proximal interphalangeal, and distal interphalangeal joints that were consistent with Gottron papules; and a spontaneous skin ulceration on the right knee.

A teenaged boy presented with a 1-year history of asymptomatic cutaneous lesions on the face that had spread to the trunk and extremities; he also had asthenia and mild intermittent arthralgias. What is your diagnosis?

This case report describes multiple small, symmetrical, reddish brown papules on the cheeks, nose, and eyelids.

This case report describes 3 patients with systemic sclerosis or mixed connective tissue disease with scleroderma features who experienced salt-and-pepper dyspigmentation that responded to treatment with mycophenolate mofetil.

This Clinical Evidence Synopsis presents key findings from a Cochrane review of interventions for cutaneous disease in systemic lupus erythematosus.

A man in his 50s presented with a depressed skin groove on his forehead and linear hair loss. Examination revealed 2 long curved alopecic patches on the left side of the vertex and frontal scalp area extending to the left eyebrow. What is your diagnosis?

This case report describes scarred erythematous patches on the labia majora, labia minora, and inguinal folds with no mucosal involvement.