Explore the latest in gynecology, including recent advances in cancer screening, family planning, management of menopause symptoms, and more.
This nested case-control study of patients enrolled in Kaiser Permanente Washington quantifies the risk of malignant ovarian cancer based on ultrasonographic characteristics of ovarian masses, including simple cysts, in a large unselected population.
This pooled analysis of individual patient data investigates the association of body mass index with subsequent breast cancer risk, in particular by age, attained age, risk factors for breast cancer, and tumor characteristics, in premenopausal women.
This randomized clinical trial assesses the efficacy of increased daily water intake vs usual fluid intake on the frequency of recurrent cystitis in premenopausal women experiencing recurrent cystitis who drink low volumes of total fluid daily.
This cohort study compares the risk for venous thromboembolism among women who use extended cyclic and continuous combined oral contraceptives (COCs) with that among women who use traditional cyclic COCs, while holding the progestogen type constant.
This phase 1 and 2 clinical trial examines progression-free survival in patients with ovarian or breast cancer treated with alisertib in combination with paclitaxel vs paclitaxel alone.
A 38-year-old woman with a history of gastric bypass surgery and hysterectomy had acute abdominal pain. Results of routine blood testing were unremarkable; a lung biopsy revealed spindle-cell fascicles with entrapped benign alveolar tissue but no necrosis, atypia, or mitotic activity. What would you do next?
This Viewpoint uses controversy over the status of statues commemorating J. Marion Sims, a Southern gynecologist who developed operative techniques for vesicovaginal fistulae on enslaved women, to discuss changing the history of attitudes toward race and discrimination in medicine and society.
This case-control study combines portions of 2 existing cohorts to investigate medial temporal lobe structure, white matter lesion load, and β-amyloid deposition in older women who underwent bilateral salpingo-oophorectomy before age 50 years and before reaching natural menopause, compared with a group of female control participants.
This study assesses whether unplanned pregnancy is associated with spontaneous fetal loss in women with epilepsy.
This prospective cohort study evaluates the 5-year risk of cervical precancer following p16/ki-67 dual-stain triage of HPV-positive women.
This cohort study uses data from the Nurses’ Health Studies to evaluate associations between use of nonsteroidal anti-inflammatory drugs and risk of epithelial ovarian cancer.
A woman in her 80s presented with somnolence, fatigue, lower urinary tract symptoms, and progressively worsening vulvar and buttock pain. What is your diagnosis?
This secondary analysis of a randomized clinical trial examines the association between driver alterations and the risk of mutations and prognosis in women with postmenopausal hormone receptor–positive, HER2-negative breast cancer.
This cross-sectional study investigates the ascertainment of pathogenic and likely pathogenic BRCA1/2 variants among US adults enrolled in the MyCode Community Health Initiative.
This randomized clinical trial compares the extent of treatment with chemotherapy and radiotherapy in women with locally advanced cervical cancer who have staging using fludeoxyglucose F 18 positron emission–computed tomography along with conventional staging with CT of the abdomen and pelvis vs those who have staging with CT alone.
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