Intraocular Inflammation

This cohort study assesses the real-world incidence of intraocular inflammation, including retinal vasculitis and/or retinal vascular occlusion for patients with neovascular age-related macular degeneration who underwent brolucizumab treatment.

A 12-year-old girl with bilateral panuveitis presented for abnormal gait. Her subsequent workup revealed elevated inflammatory markers and subcentimeter chest and abdominal lymph nodes. What would you do next?

This case report describes a teenage boy with left diffuse commotia retina, multiple choroidal ruptures, subfoveal hemorrhage, optic disc hemorrhage, and disseminated vitreous, retinal, and choroidal hemorrhage after a fireworks blast.

A 14-year-old boy had ocular and periocular pain with photophobia in his right eye. Routine blood tests showed a serum creatinine level of 1.57 mg/dL. What would you do next?

A 34-year-old woman presents with blurred vision and photophobia after having cosmetic iris implants placed 6 months earlier. What would you do next?

This survey study assesses the degree of uniformity in mapping of uveitis clinical concepts to ICD-10 codes across health care systems using the same electronic health record system.

A 50-year-old woman presents with left eye redness and headaches. Her best-corrected visual acuity is 20/20 OD and 20/25 OS. On examination, her left eye has 2 temporal scleral nodules with surrounding hyperemia and no scleromalacia. Laboratory test results show elevated levels of rheumatoid factor and C-reactive protein, and Lyme IgG, IgM, and reflex Western blot assays are positive for antibodies. Further testing shows she is negative for rheumatoid arthritis-associated nodular scleritis; however, new scleral thinning with persistence of the scleral nodules is noted. What would you do next?

This mendelian randomization and cohort study evaluates associations of tuberculosis with several noninfectious uveitis conditions, particularly Behçet disease, in cohorts in China and Japan, including a subgroup given T-SPOT.TB assays.

This case report describes a patient with coronavirus disease 2019 who experienced severe ocular neuropathy with panuveitis, resulting in permanent loss of visual acuity.

This cohort study uses ophthalmologic examination data from patients evaluated at Pointe-à-Pitre University Hospital to investigate the ocular manifestations of serologically confirmed systemic Zika virus infection.

An 81-year-old woman presents with systemic hypertension and atrial fibrillation after undergoing Descemet membrane endothelial keratoplasty. What would you do next?

This case report describes serous retinal detachments involving the macula of the right and left eyes.

This cohort study assesses the potential for uveitis recurrence, the behavior of dark without pressure, and visual outcomes in a cohort of Sierra Leonean survivors of Ebola virus disease 2 years following the 2013 to 2016 Ebola epidemic.

This case series describes diffuse or segmental ciliary body mass in 3 individuals, in whom it was a clinical sign and tissue source for biopsy in the diagnosis of ocular sarcoidosis.

This article discusses a study published in JAMA of the effect of methrotrexate vs mycophenolate as the single immunosuppressive agent on the treatment of noninfectious intermediate, posterior, and panuveitides.

An 81-year-old man presents with a gradual decline in his vision bilaterally over 2 years and a chronic cough. What would you do next?