Explore the latest in intraocular inflammation, including recent advances in the diagnosis and management of uveitis and chorioretinitis.
This randomized trial compares the effects of oral methotrexate, 25 mg weekly vs oral mycophenolate mofetil, 3 g daily, on measures of inflammation in patients with noninfectious uveitis.
This article discusses a study published in JAMA of the effect of methrotrexate vs mycophenolate as the single immunosuppressive agent on the treatment of noninfectious intermediate, posterior, and panuveitides.
This Medical News article examines the increasing incidence of herpes zoster ophthalmicus—shingles of the eye—and the need for more widespread vaccination against shingles.
An 81-year-old man presents with a gradual decline in his vision bilaterally over 2 years and a chronic cough. What would you do next?
This systematic review determines guideline efficacy by reconciling discrepancies in the incidence of endophthalmitis and evaluating outcomes of studies assessing ophthalmologic screening for candidemia.
This case series reports findings of posterior-predominant uveitis in 6 patients who were treated with ledipasvir-sofosbuvir for hepatitis C.
This case series assesses the utility of metagenomic deep sequencing in identifying rubella virus infection in patients with uveitis.
This secondary analysis of data from a phase 1/2 clinical trial examines the association between immune response and intraocular inflammation after ocular gene therapy with recombinant adeno-associated virus 2 carrying the ND4 gene in patients with Leber hereditary optic neuropathy.
This case report describes a young adult with a retinal-choroidal anastomosis secondary to toxoplasmosis chorioretinitis in early childhood.
A 50-year-old woman presented to the ophthalmology clinic with more than 9 months of eye pain and redness in both eyes despite receiving treatment after a hospitalization for pneumonia, myocarditis, and hypereosinophilic syndrome. What would you do next?
A 26-year-old white man had recurrent episodes of ocular redness and blurry vision coincident with nodular skin elevation in a left-arm tattoo. Slit lamp examination revealed inflammatory cells in the anterior chamber of the left eye; punch biopsy of the tattooed skin revealed pigment-containing macrophages. What is the diagnosis and what would you do next?
This case of a woman with idiopathic retinal vasculitis, aneurysms, and neuroretinitis reports findings before and after diagnosis.
This case-control study examines the association between uveitis and psychological stress in patients with active and controlled uveitis.
A white man in his mid-80s with an ocular history of remote left cataract extraction was referred for possible birdshot chorioretinopathy. Multiple yellow-white subretinal deposits were scattered throughout the left posterior pole with parafoveal coalescence, and optical coherence tomography showed choroidal thickening and irregularity of the overlying retinal pigment epithelium. What would you do next?
This study of 3 patients with birdshot chorioretinopathy tests the feasibility of swept-source optical coherence tomography angiography in the detection of choroidal lesions.
This case report describes a pediatric patient with an unusual cause of eye pain and loss of visual acuity after hospitalization for seizures and meningoencephalitis.
This analysis of 2 electronic health care systems compares ICD-10 coding of 27 uveitis diseases to identify discrepancies in coding.
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