Explore the latest in pharmacoepidemiology, including population studies of drug utilization and safety, comparative effectiveness research, and more.
This cross-sectional study uses data from the National Center for Health Statistics to identify changes in the geographical distribution of opioid-related mortality across the United States by opioid type.
This survey study evaluates the frequency of sales of over-the-counter insulin at US pharmacies.
This case-control study examines the association between the use of dipeptidyl peptidase 4 inhibitors and the risk of developing bullous pemphigoid in patients with diabetes.
This population-based cohort study investigates the prescribing patterns for combined dextromethorphan hydrobromide and quinidine sulfate after regulatory approval for treatment of pseudobulbar affect in patients with dementia and/or Parkinson disease.
This cohort study examines the incidence of myocardial infarction, stroke, and death in patients with exudative age-related macular degeneration receiving intravitreal anti–vascular endothelial growth factor injections compared with control individuals who did not receive the injections.
This study examines whether using aripiprazole for the first time or adding it to a treatment regimen lead to serious outcomes for patients with a history of taking antipsychotic medications.
This cross-sectional study uses data from the National Ambulatory Medical Care Survey to quantify patterns in outpatient benzodiazepine prescribing and compare them across specialties and indications.
This cross-sectional inventory study assesses the quantity and trends of several different opioids prescribed and dispensed for small animals and exotic species during the past 12 years in a large veterinary hospital in Philadelphia, Pennsylvania.
This series of within-individual cohort studies assesses whether hydroxylmethyl glutaryl coenzyme A (HMG-CoA) reductase inhibitors, L-type calcium channel antagonists, and biguanides are associated with reduced rates of psychiatric hospitalization and self-harm in individuals with serious mental illness.
This population-based cohort study of children in Denmark evaluates whether maternal use of valproate or other antiepileptic drugs during pregnancy is associated with the risk of attention-deficit/hyperactivity disorder (ADHD) in offspring.
This cohort study examines the trend in prescription testosterone use among male Medicare beneficiaries with and without coronary artery disease aged 50 years or older.
This cross-sectional study evaluates the changes in the mortality rates among US children and adolescents who died from prescription and illicit opioid poisonings between 1999 and 2016.
This cohort study examines the associations of second-line antidiabetic medication classes with major adverse cardiovascular events in adults with type 2 diabetes.
This cross-sectional study examines patterns of opioid prescription to US pediatric patients during visits to hospital emergency departments between 2006 and 2015 using data from the National Hospital Ambulatory Medical Care Survey.
This cohort study uses Medicaid data to estimate the role of congenital malformations among the offspring of women who took ondansetron during the first 3 months of pregnancy (between 2000 and 2013).
This systematic review and meta-analysis examines randomized clinical trials (RCTs) of modern cancer drugs in the adjuvant setting to determine the incidence of severe adverse events reported in placebo groups.
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