Explore the latest in respiratory failure and ventilation, including definitions and management of ARDS, noninvasive ventilation, and more.
This narrative review analyzes existing research and clinical guidelines associated with the occurrence of cardiac arrest and the use of cardiopulmonary resuscitation in hospitalized children and adolescents.
This cohort study evaluates whether patients with COVID-19 have a higher incidence of full-thickness tracheal lesions and tracheoesophageal fistulas than matched controls and investigates potential mechanisms.
This case series describes 2 patients with coronavirus disease 2019 and orbital compartment syndrome, optic disc edema, and retinal hemorrhage in the setting of prolonged prone positioning in the intensive care unit.
This case-control study examines the association of COVID-19 with the respiratory muscles in Dutch critically ill patients.
This randomized trial compares the effects of fluvoxamine, a selective serotonin reuptake inhibitor with immunomodulatory effects vs placebo on a composite of dyspnea or pneumonia and oxygen desaturation among adult outpatients with polymerase chain reaction–confirmed mild coronavirus disease 2019 (COVID-19) illness.
This randomized clinical trial compares the ability to prevent intubation in preterm infants by using nasal intermittent positive pressure ventilation for the initial treatment of respiratory distress syndrome or postextubation with either a cannula with long and narrow tubing or short binasal prong and mask interfaces.
This randomized trial compares the effects of hydroxychloroquine vs placebo on clinical status at 14 days (home, requiring noninvasive or invasive ventilation or extracorporeal membrane oxygenation, hospitalized, died) among adults hospitalized with coronavirus disease 2019 (COVID-19).
This cohort study investigates whether the prone position is associated with improved oxygenation and decreased risk for intubation in spontaneously breathing patients with severe COVID-19 hypoxemic respiratory failure.
A 9-year-old boy presents with progressive dyspnea, snoring, dysphagia, and weight loss; biopsy and culture results revealed diffuse non-necrotizing granulomas and oropharyngeal flora with negative acid-fast bacilli and Grocott methenamine silver stains. What is your diagnosis?
This cohort study assesses mortality rates among patients with COVID-19 admitted to intensive care who were treated with tocilizumab.
This randomized clinical trial evaluates the effect of early tocilizumab administration vs standard therapy in preventing clinical worsening in patients hospitalized with COVID-19.
This randomized clinical trial examines the effects of tocilizumab vs usual care in patients hospitalized with COVID-19 and moderate-to-severe pneumonia.
This cohort study describes the ventilatory support provided within 30 days of death in older adults with chronic obstructive pulmonary disease, congestive heart failure, cancer, or dementia.
This review synthesizes the literature regarding tracheostomy and laryngectomy management in the context of the COVID-19 pandemic.
This cohort study assesses the complications, safety, and timing of tracheotomy performed for critically ill patients with COVID-19.
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