Explore the latest in retinal disorders from The JAMA Network, including recent advances in treatment of age-related macular degeneration and diabetic retinopathy.
A woman in her 30s was referred for evaluation of severe bilateral optic disc edema, retinal hemorrhages, and a gradual decrease in vision during a 3-week period. What would you do next?
This case series study investigates whether the aqueous humor of retinoblastoma eyes has sufficient tumor-derived DNA to perform genetic analysis of the tumor, including DNA copy number alterations.
This multicenter cohort study describes the yearly progression rate of atrophic lesions as determined by fundus autofluorescence in the retrospective Progression of Stargardt Disease study.
This study examines the prevalence of age-related macular degeneration in Australia.
A woman in her late 20s presented with blurry vision in both eyes. A dilated ophthalmoscopic examination revealed mild optic nerve pallor and bilateral serous macular detachment. What would you do next?
This case report is about the ophthalmic manifestations of hemophagocytic lymphohistiocytosis, a rare and often fatal disease commonly seen in infants.
This case series assesses the visual function of 3 patients with sickle cell disease and temporal macular atrophy but with no visual symptoms.
This population-based study examines the prevalence of and risk factors for retinal emboli and associations with ethnicity, stroke, and renal disease in a large, contemporary, multiethnic Asian population.
This cross-sectional study describes the phenotypical characteristics of patients with age-related macular degeneration carrying a rare variant in the complement factor H gene.
This study uses the SEER database to explore the clinical characteristics of diffuse large B-cell lymphoma and determine factors associated with overall survival among patients with primary vitreoretinal and ocular adnexal–uveal disease.
This case series quantifies the microstructural changes of the retina in infants with congenital Zika syndrome following Zika exposure in utero.
This cross-sectional study evaluates the repeatability and reproducibility of optical coherence tomographic angiography–derived retinal vascular quantitative metrics in patients with retinal disease.
This case series describes initial and serial multimodal imaging findings in acute macular neuroretinopathy with attention to choroidal vascular changes.
This study uses deep learning methods for the automated assessment of age-related macular degeneration from color fundus images.