Explore the latest in anticoagulation, including dosing, safety, and reversal of newer oral agents, periprocedural management, and more.
This randomized clinical trial evaluated whether a biomarker-driven, risk-directed approach to thromboprophylaxis would prevent thromboembolism among adults with lung and gastrointestinal (GI) cancers receiving anticancer therapies in ambulatory treatment settings.
This cohort study compares clinical outcomes for patients undergoing extended anticoagulation therapy with warfarin vs direct oral anticoagulants for treatment of venous thromboembolism (VTE).
This cohort study examines the prevalence of and eligibility for structured surveillance of adult outpatients with acute subsegmental pulmonary embolism, according to modified American College of Chest Physicians criteria.
This comparative effectiveness research assesses patterns of and factors associated with anticoagulant use and evaluates the risk of venous thromboembolism among patients with active cancer.
This cohort study compares outcomes associated with 3 direct oral anticoagulant care (DOAC) models for preventing adverse anticoagulation-related outcomes among patients with atrial fibrillation.
This randomized clinical trial of individuals with ischemic stroke assesses the safety and efficacy of treatment with a dual plasminogen activator vs usual treatment with intravenous alteplase.
This retrospective cohort study assesses the association between recent use of oral vitamin K antagonists and symptomatic intracranial hemorrhage among patients with acute ischemic stroke undergoing endovascular thrombectomy.
This randomized trial assesses the comparative effectiveness of direct oral anticoagulants vs low-molecular-weight heparin on rate of 6-month recurrence of venous thromboembolism (VTE) among patients with cancer who had a new diagnosis of VTE.
This secondary analysis of a cluster randomized crossover trial compares aspirin with enoxaparin as venous thromboembolism prophylaxis in reducing 90-day mortality for patients undergoing hip or knee arthroplasty.
This cohort study examines whether underdosing of direct oral anticoagulants not recommended by the Food and Drug Administration is associated with longitudinal adherence to anticoagulation treatment among patients with nonvalvular atrial fibrillation (NVAF).
This randomized clinical trial compares the effects of high-dose, standard-dose, and therapeutic anticoagulation on mortality and/or disease duration among patients with hypoxemic COVID-19 pneumonia in 23 hospitals in France.
This JAMA Oncology Patient Page explains the risk, diagnosis, treatment, and prevention of thrombosis in patients with cancer.
This randomized clinical trial assesses the efficacy and safety of rivaroxaban as postoperative thromboprophylaxis in patients undergoing bariatric surgery.
This cohort study investigates time trends in patient characteristics, anticoagulation treatment, and prognosis of patients with incident nonvalvular atrial fibrillation in the Netherlands.
This cohort study assesses the perceptions of patients with atrial fibrillation and their physicians about the benefits and risks of anticoagulation.
This cohort study uses national claims data to describe platelet ADP P2Y12 receptor inhibitor choice and switching among patients who underwent percutaneous coronary intervention for acute coronary syndrome.
This exploratory study of a multiplatform randomized trial investigating the effects of therapeutic-dose heparin in early-pandemic hospitalized COVID-19 patients describes findings from 3 statistical approaches to detecting differences of treatment effect in clinically relevant patient subgroups.
This comparative effectiveness study uses data from 3 US claims databases to assess the comparative safety and effectiveness of specific oral anticoagulant therapies by dementia status among older patients with atrial fibrillation.
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