Explore the latest in anticoagulation from The JAMA Network, including dosing, safety, and reversal of newer oral agents, periprocedural management, and more.
This review provides an evidence-based update on the perioperative management of patients receiving non–vitamin K oral anticoagulant therapy.
This cohort study assesses whether continued preoperative aspirin use preoperatively is associated with increased bleeding complications among patients undergoing thyroid surgery.
This case report describes 3 patients treated with lenalidomide as an alternative to thalidomide for recurrent erythema multiforme.
This randomized clinical trial evaluates the short-term safety of ticagrelor when compared with clopidogrel in patients with ST-elevation myocardial infarction treated with fibrinolytic therapy.
This randomized clinical trial compares anticoagulation vs antiplatelet therapy in patients with cancer and acute ischemic stroke.
This review of 304 carpal tunnel release procedures examines the necessity of stopping antithrombotic medications prior to carpal tunnel release surgery.
This meta-analysis assesses the efficacy and safety of direct oral anticoagulants in addition to background antiplatelet therapy for secondary prevention in patients with acute coronary syndrome.
This multicenter study investigates the incidence of delayed traumatic intracranial hemorrhage in older adults with head trauma and specifically across anticoagulant and antiplatelet medications.
A 45-year-old man with superior mesenteric vein thrombosis (SMVT) and with mesenteric ischemia was treated with partial small bowel resection and 2 weeks of enoxaparin. Three weeks later, he underwent bowel resection for recurrent SMVT and developed venous thromboembolism on intravenous heparin. Lab results were consistent with heparin-induced thrombocytopenia (4Ts score, 6). What would you do next?
This cohort study compares the association between use of warfarin vs non–vitamin K oral anticoagulants (NOACs) and in-hospital mortality among patients with intracerebral hemorrhage.
This cohort study uses a large national insurance claims database to determine the risk of developing intraocular hemorrhages with novel oral antithrombotic therapy compared with traditional antithrombotic agents.
This systematic review uses the MEDLINE and EMBASE databases to identify the available therapies for livedoid vasculopathy and their clinical outcomes.
This study assesses whether anti–factor Xa–guided dosing, compared with standard dosing, reduces the rate of venous thromboembolism in adults admitted to a level I trauma intensive care unit.
This population-based cohort study uses the Norwegian national registries to determine the association between warfarin use and cancer incidence among persons aged 52 to 82 years.
This randomized clinical trial evaluates whether chewing a loading dose of ticagrelor, 180 mg, vs traditional oral administration of an equal dose enhances platelet inhibition at 30 minutes and 1 hour after loading dose administration in patients with ST-segment elevation myocardial infarction.
This secondary analysis reports on the association of low-dose and standard-dose intravenous alteplase treatment with age, ethnicity (Asian vs non-Asian), and severity of acute ischemic stroke among patients in the ENCHANTED randomized clinical trial.
This systematic review and meta-analysis compares the clinical effectiveness of coronary computed tomography angiography with that of functional stress testing for patients with suspected coronary artery disease.
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