Explore the latest in gastroenterology and hepatology, including recent advances in treatment of viral hepatitis and of GI and pancreatic cancers.
This narrative review examines treatment and management of cystic fibrosis.
This observational study describes the prevalence of germline genetic testing in California and Georgia between 2013 and 2019 among patients diagnosed with cancer.
This cross-sectional study with a nested cohort assesses the number of screening colonoscopies done in patients older than 75 years with a life expectancy of fewer than 10 years.
This randomized crossover trial evaluates the effectiveness of fluoropyrimidine-based systemic chemotherapy in patients with inoperable low-grade mucinous appendiceal adenocarcinoma.
This cohort study examines the association between physical fitness and subsequent risk for inflammatory bowel disease among children and adolescents in Taiwan.
This randomized clinical trial assesses progression-free survival among patients with RAS wild-type metastatic colorectal cancer receiving panitumumab plus standard-of-care trifluridine-tipiracil as third-line therapy.
This case series assesses the gene-specific risk estimates of development of pancreatic ductal adenocarcinoma (PDAC) and extra-PDAC among first-degree relatives of patients with PDAC who carry pathogenic or likely pathogenic germline variants in cancer syndrome–associated genes.
This randomized clinical trial compares the efficacy and safety of simultaneous integrated boost radiotherapy with concurrent and consolidated oral S-1 chemotherapy vs radiotherapy alone for patients aged 70 years and older with inoperable esophageal squamous cell carcinoma.
This Viewpoint describes new recommendations from the CDC regarding universal screening of adults for hepatitis B virus infection.
This Viewpoint outlines the progress made toward eliminating hepatitis B and C but emphasizes the work that remains to prioritize diagnosis and treatment of populations disproportionately affected by viral hepatitis, including ensuring that there are systems in place to treat those infected and care for those at risk.
This cohort study examines changes in probiotic use among neonates with very low birth weight in US neonatal intensive care units (NICUs) between 2012 and 2019 and the association of routine probiotic use in this population with health outcomes.
This cohort study assesses quality of life and functional outcome of patients with rectal cancer who are followed up via a watch-and-wait approach.
This cohort study of Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial data examined the association between gastrointestinal cancer and body mass index in adulthood and the association between changing body mass index and cancer risk.
This randomized clinical trial assesses the effect of administration of prophylactic amoxicillin-clavulanate vs placebo on 60-day mortality in patients hospitalized with severe alcohol-related hepatitis.
This phase 3 randomized clinical trial examines the effect of broad-spectrum perioperative antimicrobial prophylaxis on postoperative surgical site infection incidence compared with standard care antibiotics (cefoxitin).
A 70-year-old woman with hypertension, atrial fibrillation, congestive heart failure, and gallstones had 3 days of nausea, vomiting, and abdominal pain. Abdominal computed tomography showed a thickened gallbladder wall with intraluminal air adherent to the duodenum and a gallstone in the middle ileum with proximal bowel distension. What is the diagnosis and what would you do next?
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