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    Pain Medicine

    Explore the latest in pain medicine, including the latest in procedural management of back and spine pain and guidelines for use of opioids.

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    • Surgeons’ Perspectives on Changing the Default Number of Doses for Opioid Prescriptions in Electronic Health Record Systems
      JAMA Network Open
      Research
      May 26, 2023

      This qualitative study assesses surgeons’ perspectives regarding a change in the default number of doses for opioid prescriptions written through an electronic health record system to adolescents and young adults undergoing tonsillectomy.

      Health Policy Health Informatics Otolaryngology Substance Use and Addiction Medicine Opioids
      Full Text | pdf link PDF open access
    • Limited Evidence Backs Antidepressant Use for Managing Chronic Pain
      JAMA
      News
      May 24, 2023
      Full Text | pdf link PDF free
    • Reducing Opioid Use for Chronic Pain With a Group-Based Intervention: A Randomized Clinical Trial
      JAMA
      Research
      May 23, 2023

      This randomized clinical trial compares the efficacy of a multicomponent, group-based, self-management intervention vs usual care in reducing opioid use and improving pain-related disability in patients taking strong opioids to treat chronic pain from nonmalignant causes.

      Substance Use and Addiction Medicine Opioids
      Full Text | pdf link PDF
    • Prescribing Opioids for Pain
      JAMA
      Review
      May 23, 2023

      This JAMA Clinical Guidelines Synopsis summarizes the Centers for Disease Control and Prevention’s 2022 clinical practice guideline for prescribing opioids for pain.

      Guidelines Substance Use and Addiction Medicine Opioids
      Full Text | pdf link PDF | CME & MOC is active quiz
    • Assessment of Initial Depressive State and Pain Relief With Ketamine in Patients With Chronic Refractory Pain
      JAMA Network Open
      Research
      May 19, 2023

      This cohort study examines clinical pain trajectories with repeated ketamine administration to explore whether racemic ketamine dose, pretreatment depressive, or pretreatment anxiety symptoms mediate pain relief in patients with treatment-resistant chronic pain.

      Anesthesiology Clinical Pharmacy and Pharmacology Pharmacy and Clinical Pharmacology Psychiatry and Behavioral Health Depressive Disorders
      Full Text | pdf link PDF open access
    • Associations of Co-occurring Symptom Trajectories With Sex, Race, Ethnicity, and Health Care Utilization in Children
      JAMA Network Open
      Research
      May 18, 2023

      This cohort study assesses co-occurring pain, psychological, and sleep disturbance symptom trajectories in a diverse cohort of children and the association of symptom trajectory with health care utilization

      Pediatrics Health Disparities Sleep Medicine Child and Adolescent Psychiatry Health Policy
      Full Text | pdf link PDF open access
    • Examining Mental Health, Education, Employment, and Pain in Sickle Cell Disease
      JAMA Network Open
      Research
      May 18, 2023

      This cross-sectional study examines the associations of educational attainment, employment status, and mental health with pain episode frequency and severity among individuals with sickle cell disease.

      Hematology Psychiatry and Behavioral Health Sickle Cell Disease
      Full Text | pdf link PDF open access
    • Estimated Rates of Incident and Persistent Chronic Pain Among US Adults, 2019-2020
      JAMA Network Open
      Research
      May 16, 2023

      This cohort study uses data from the 2019-2020 National Health Interview Survey Longitudinal Cohort to assess rates of incident and persistent chronic pain and high-impact chronic pain among US adults across demographic groups.

      Neurology
      Full Text | pdf link PDF open access
    • Sciatica Surgery Only Temporarily Lessens Pain, Disability
      JAMA
      News
      May 16, 2023
      Neuropathy Orthopedics Surgery
      Full Text | pdf link PDF
    • Are We Undertreating Pain—A Review of the CDC 2022 Opioid Prescription Guidelines in the Context of Otolaryngology
      JAMA Otolaryngology–Head & Neck Surgery
      Opinion
      May 1, 2023

      This Viewpoint discusses the 2022 Centers for Disease Control and Prevention guidelines for opioid prescription in the context of otolaryngology.

      Otolaryngology Head and Neck Surgery Substance Use and Addiction Medicine Opioids
      Full Text | pdf link PDF
    • Meta-analysis: Analgesics’ Value for Lower Back Pain Uncertain
      JAMA
      News
      April 25, 2023
      Clinical Pharmacy and Pharmacology Emergency Medicine Rheumatology
      Full Text | pdf link PDF free
    • Efficacy and Safety of Esketamine for Supplemental Analgesia During Elective Cesarean Delivery: A Randomized Clinical Trial
      JAMA Network Open
      Research
      April 21, 2023

      This randomized clinical trial investigates the sedative and analgesic effects of intravenous esketamine used before childbirth via cesarean delivery with epidural anesthesia in women in China.

      Anesthesiology Women's Health Obstetrics and Gynecology Pregnancy Obstetrics
      Full Text | pdf link PDF open access
    • Routine Prophylactic Esketamine for the Prevention of Maternal Pain During Cesarean Delivery
      JAMA Network Open
      Opinion
      April 21, 2023
      Anesthesiology Neonatology Pediatrics Women's Health Obstetrics and Gynecology
      Full Text | pdf link PDF open access
    • Stereotactic Radiosurgery vs Conventional Radiotherapy for Localized Vertebral Metastases of the Spine: Phase 3 Results of NRG Oncology/RTOG 0631 Randomized Clinical Trial
      JAMA Oncology
      Research
      April 20, 2023

      This randomized clinical trial assesses whether patient-reported pain relief was improved with stereotactic radiosurgery compared with conventional external beam radiotherapy for patients with 1 to 3 sites of vertebral metastases.

      Oncology Surgery Surgical Oncology Radiation Oncology Neurology
      Full Text | pdf link PDF has multimedia
    • Etiology, Diagnosis, and Modern Management of Chronic Pancreatitis: A Systematic Review
      JAMA Surgery
      Review
      April 19, 2023

      This systematic review investigates the common risk factors, etiologies, manifestations, and treatment modalities for patients with chronic pancreatitis.

      Substance Use and Addiction Medicine Surgery Alcohol Anesthesiology Gastroenterology and Hepatology
      Full Text | pdf link PDF | CME & MOC is active quiz
    • Long-term Outcomes Following a Comprehensive Quality Assurance and Process Improvement Endeavor to Minimize Opioid Use After Kidney Transplant
      JAMA Surgery
      Research
      April 5, 2023

      This quality improvement study evaluated the long-term outcomes associated with an opioid-sparing protocol in adult kidney graft recipients.

      Anesthesiology Health Care Quality Surgery Transplantation Opioids
      Full Text | pdf link PDF
    • Comparison of Postpartum Opioid Prescriptions Before vs During the COVID-19 Pandemic
      JAMA Network Open
      Research
      April 3, 2023

      This cross-sectional study of privately insured women compares postpartum opioid prescription fills after the onset of the COVID-19 pandemic in March 2020 with fills before the pandemic.

      Obstetrics and Gynecology Pregnancy Obstetrics Pharmacoepidemiology Substance Use and Addiction Medicine
      Full Text | pdf link PDF open access
    • Implementation and Assessment of No Opioid Prescription Strategy at Discharge After Major Urologic Cancer Surgery
      JAMA Surgery
      Research
      April 1, 2023

      This cohort study assesses a protocol for eliminating postdischarge opioid prescriptions after major urologic cancer surgery by assessing patients who receive usual, reduced, or no opioids.

      Surgery Surgical Oncology Urology Urologic Cancer Perioperative Care and Consultation
      Full Text | pdf link PDF
    • Chronic Pain at Multiple Sites Tied to Increased Dementia Risk
      JAMA
      News
      March 21, 2023
      Dementia and Cognitive Impairment Neurology
      Full Text | pdf link PDF
    • Association of Primary Care Visit Length With Potentially Inappropriate Prescribing
      JAMA Health Forum
      Research
      March 10, 2023

      This cross-sectional study of a multistate sample of electronic health record data examines the association between primary care visit length and potentially inappropriate prescribing.

      Health Policy Health Disparities Health Inequities Health Care Quality Antibiotic Use, Overuse, Resistance, Stewardship
      Full Text | pdf link PDF open access
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