Explore the latest in pain medicine, including the latest in procedural management of back and spine pain and guidelines for use of opioids.
This case-control cohort study compares the total number of opioid pain medications prescribed after gynecologic and abdominal surgery, the number of requests for opioid prescription refills, and postoperative pain scores and complications before and after implementation of an ultrarestrictive opioid prescription protocol.
This narrative review addresses the rewarding and analgesic effects of opioids, the epidemiology of the opioid crisis, and interventions used to treat and prevent opioid use disorder.
In this narrative medicine essay, the author shares how he assembled the tools to help him manage his pain from fibromyalgia and argues for reuniting pain medicine with compassion.
This cohort study using the Optum Research Database examines whether opioid prescriptions provided by dental clinicians for pain management of third molar extractions to opioid-naive US adolescents and young adults was associated with subsequent opioid use and abuse.
This Special Communication, the fifth annual update on medical overuse, discusses 10 studies published in 2017 that are most relevant to understanding medical overuse in adults.
This Medical News & Perspectives article discusses recently enacted state laws that allow prescribed opioids to be substituted with medical marijuana.
This pharmacoepidemiology study describes trends in first prescriptions for gabapentin and pregabalin in UK primary care practices and rates of these prescriptions for an off-label indication or with coprescription of opioids or benzodiazepines between 1993 and 2017.
This systematic review identifies 238 trials of pregabalin for nonapproved indications and examines how often exploratory trials generate a suggestion of efficacy but are not followed up by confirmatory trials.
This study uses data from the Optum Clinformatics Data Mart to evaluate trends in outpatient prescription of opioids to persons 18 years or younger in the United States from 2004 to 2017.
This Viewpoint discusses genetic models of trigeminal neuralgia pathogenesis.
This randomized, placebo-controlled clinical trial compares the effects of intensive vs placebo patient education as a part of first-line care among patients with acute low back pain who were recruited between 2013 and 2015 from various institutions in Sydney, Australia.
This randomized clinical trial investigates the effect of perioperative gabapentin treatment vs placebo on postsurgical pain in patients undergoing head and neck mucosal surgery.
This matched cohort study examines the association of the addition of celecoxib to the standard analgesia regimen with opioid use in patients after head and neck cancer surgery.
This cohort study assesses the association of institutional availability of multimodal analgesia pathways with adoption and adherence to such pathways, and the frequency of opioid prescriptions at discharge among adults following thyroid and parathyroid surgery.
This observational study compares postoperative use of opioids between the United States and Hong Kong in patients undergoing head and neck surgery.
This randomized clinical trial examines the efficacy of low-dose amitriptyline vs an active comparator in reducing pain, disability, and work absence and hindrance in individuals with chronic low back pain.
This study examines findings from decades of published research to determine whether use of cannabinoid analgesia is associated with experimental pain relief among healthy adults.
This meta-analysis of participant-level data assesses the effect of placebo treatments on pain-associated functional neuroimaging responses in the neurologic pain signature, a multivariate brain pattern tracking nociceptive pain.
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