Explore the latest in pathology and laboratory medicine, including AI applications to biopsy readings, diagnostic test interpretation, and more.
A white woman in her 70s with Alzheimer disease presented with a high hemoglobin level and red blood cell count as well as erythematous macular eruption over the trunk and limbs. What is your diagnosis?
This cohort study examines the prevalence of benign pathologic findings among adults after partial nephrectomy and potential risk factors associated with this prevelence.
A 68-year-old woman with chronic lymphocytic leukemia (CLL) presents with dyspnea on exertion, conjunctival pallor and scleral icterus, and moderate anemia with elevated reticulocytes and LDH and a 3+ anti-IgG direct antiglobulin test (DAT). How do you interpret the results?
This multicenter cohort study examines the outcomes and risk for the development of subsequent cutaneous melanoma in moderately dysplastic nevi excisionally biopsied without residual clinical pigmentation but with positive histologic margins, observed for 3 years or more.
This study assesses the rate and utility of monitoring laboratory test result abnormalities in adults and children taking terbinafine and griseofulvin for treatment of dermatophyte infections.
A 38-year-old woman with a history of gastric bypass surgery and hysterectomy had acute abdominal pain. Results of routine blood testing were unremarkable; a lung biopsy revealed spindle-cell fascicles with entrapped benign alveolar tissue but no necrosis, atypia, or mitotic activity. What would you do next?
This cross-sectional study uses data from the Medical Information Mart for Intensive Care database to investigate how laboratory values of patients in the intensive care unit (ICU) differ from the standard reference range and to examine whether these differences are associated with mortality and length of stay in the ICU.
This study investigates the utility of reinterpreting the genomic test results of pediatric patients who previously underwent genomic epilepsy testing.
This cohort study evaluated associations of increased creatinine levels, hyperkalemia, and continuation of therapy with the risk of emergency department visits, hospitalizations, and mortality within 1 year after initiation of renin angiotensin aldosterone system inhibitor (RAASI) therapy in patients with chronic kidney disease.
This Insights discusses the necessity of completion node dissection after sentinel node biopsy in patients with melanoma.
This study searched ClinicalTrials.gov to examine the reporting rates of research biopsies conducted in oncology clinical trials amd investigates what factors correlate with research biopsy reporting.
This case study investigates the presence of the GNAQ R183Q mutation in the choroidal vessels of a patient with Sturge-Weber syndrome.
This prospective cohort study evaluates the 5-year risk of cervical precancer following p16/ki-67 dual-stain triage of HPV-positive women.
A 74-year-old man taking rivaroxaban for atrial fibrillation developed a subdural hematoma and had an elevated prothrombin time (PT) with normal activated partial thromboplastin time (aPTT) and platelets prior to planned surgical evacuation. How do you interpret the results?
This cohort study of patients in 4 European countries and the United States with resected pancreatic ductal adenocarcinoma assesses the validity of the eighth edition of the American Joint Committee on Cancer TNM staging system compared with the seventh edition.
This Viewpoint discusses emerging therapies for X-linked adrenoleukodystrophy, an inherited disorder affecting the adrenals and nervous system white matter, and empahsizes the importance of newborn screening.
This Viewpoint discusses how expert review of breast pathology in borderline lesions may offer the opportunity to reduce overdiagnosis and overtreatment of breast cancer.
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