Explore JAMA Network Open’s collection on clinical pharmacy and pharmacology, including topics in drug safety and development, pharmacogenetics, and more.
This cross-sectional study characterizes trends in ambulatory insulin use, overall and based on insulin characteristics, among adults with type 2 diabetes in the United States from 2016 to 2020.
This systematic review and network meta-analysis of randomized clinical trials compares outcomes associated with the use of lasmiditan, rimegepant, and ubrogepant vs triptans for acute management of migraine headaches.
This randomized clinical trial examines the effect of medication reconciliation on unplanned hospital returns among Swiss patients who were older, had polypharmacy, or met both conditions.
This cohort study compares the safety and clinical outcomes associated with chlorthalidone vs hydrochlorothiazide use among older adults with varying levels of kidney function.
This cohort study examines whether proton pump inhibitor use during pregnancy is associated with the rate of preeclampsia.
This cohort study investigates whether serious hypoglycemia is reduced in a Medicaid population receiving calcium-channel blockers with insulin secretagogues.
This randomized clinical trial examines the effect of the use of pictorial information including carotid ultrasonographic images with explanation on prescribing of lipid-lowering and antihypertensive drugs.
This cohort study compares the risk of stroke and/or systemic embolism and major bleeding among patients with nonvalvular atrial fibrillation and high risk of gastrointestinal bleeding who received non–vitamin K antagonist oral anticoagulants vs warfarin.
This systematic review and network meta-analysis assesses neuraminidase inhibitors and an endonuclease inhibitor for safety and efficacy against seasonal influenza in children and adults.
This cohort study assesses whether the number of hospitalists providing care is associated with subsequent hospital complications and length of stay.
This population-based cohort study examines the association between the initial wave of the COVID-19 pandemic and changes in medication dispensation patterns among nursing home residents in the province of Ontario, Canada.
This economic evaluation examined the cost-effectiveness of adding dapagliflozin to guideline-directed medical therapy for heart failure with reduced ejection fraction in a simulated cohort of patients with or without diabetes.
This cohort study examines how primary care physicians’ personal formularies differ at 4 institutions; evaluates associations between personal formularies and patient, physician, and practice site characteristics; and examines the variability of the top 200 core drugs prescribed at the 4 sites.
This study characterizes N-nitrosodimethylamine (NDMA) formation following the addition of ranitidine to simulated gastric fluid using combinations of fluid volume, pH levels, and nitrite concentrations, including physiologic levels.
This cross-sectional study uses data from the National Health and Nutrition Examination Survey to assess the prevalence of aspirin use among older adults in the US with and without diabetes.
This cross-sectional study evaluates the prevalence of proton pump inhibitor use among patients with cancer at 4 French comprehensive cancer centers.
This population-based cohort study assesses the clinical implications of discontinuing the use of statins while maintaining other drugs in a cohort of older patients receiving polypharmacy.
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