Explore JAMA Network Open’s collection on clinical pharmacy and pharmacology, including topics in drug safety and development, pharmacogenetics, and more.
This cross-sectional study describes the characteristics of abbreviated new drug applications approved by the US Food and Drug Administration, focusing on those with limited generic competition or with history of shortages.
This cluster randomized trial evaluates whether electronic medication reconciliation reduces medication discrepancies, adverse drug events, and other adverse outcomes compared with usual care.
This interrupted time series analysis and cross-sectional study examines changes in alprazolam prescribing patterns after a national policy change that reduced alprazolam subsidies in Australia.
This cross-sectional study uses data from the Veterans Health Administration and Medicaid to examine changes in varenicline prescribing from the time of US Food and Drug Administration (FDA) approval through publication and removal of public health advisories.
This systematic review and meta-analysis evaluates results of 12 randomized clinical trials, comparing changes in lean body mass in 4474 postmenopausal women who were vs were not receiving estrogen-based hormone therapy.
This multicenter nonrandomized clinical trial with crossover design study determines the feasibility and results of implementing 2 core stewardship intervention strategies, preauthorization and postprescription audit and review, in community hospitals.
This population-based cohort study examines the sex-based variations in burdensome interventions (care transitions, invasive procedures, and use of physical restraints) and antibiotic therapy at the very end of life among nursing home residents with advanced dementia in Ontario, Canada.
This case series uses data from the US Food and Drug Administration’s Adverse Event Reporting System to assess the postmarketing safety profile of sipuleucel-T.
This cohort study evaluates whether the 2016 release of the Centers for Disease Control and Prevention (CDC) guidelines for opioid prescribing was associated with changes in the rates of opioid and benzodiazepine coprescription among commercially insured patients and US Medicare Advantage beneficiaries.
This cohort study examines the use of antipsychotic medication in youths, aged 3 to 24 years, following a new diagnosis of attention-deficit/hyperactivity disorder.
This quality improvement study examines whether over-the-counter medication dispensing behavior in Australian pharmacies complies or conflicts with the protocols indicated in practice standards and guidelines of a national professional pharmacy organization.
This cross-sectional study examines changes in revenues of manufacturers of drugs for treatment of hepatitis C and health care organizations after list price reductions.
This cohort study uses data from the Surveillance, Epidemiology, and End Results (SEER)–Medicare database to investigate the association between androgen deprivation therapy and diagnosis of Alzheimer disease or dementia among elderly men with prostate cancer.
This cohort study of Japanese participants with acute decompensated heart failure in the Kyoto Congestive Heart Failure study evaluates the association of mineralocorticoid receptor antagonist use with all-cause mortality and hospital readmission.
This population-based cohort study examines the rates of naloxone coprescription since implementation of state laws mandating coprescription for persons at risk for opioid overdose.
This cross-sectional analysis of the Disclosure UK database examines the concentration and patterns of drug company payments to health care organizations in the United Kingdom.
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