Explore this JAMA Internal Medicine series documenting the ways that overuse of medical care fails to improve outcomes, harms patients, and wastes resources.
This randomized clinical trial examines the impact of electronic decision support on postdischarge adverse drug events and deprescribing among hospitalized patients 65 years or older at 11 hospitals in Canada.
This cross-sectional study characterizes the prevalent use of medications that may raise BP and examine their associations with BP control and antihypertensive use.
This qualitative study examines the characteristics and expected impact of 626 Choosing Wisely recommendations.
This cohort study analyzes inpatient and outpatient episodes of procedural and surgical care to assess the prevalence and costs of low-value preprocedural urinalyses in the US from 2007 to 2017.
This cross-sectional study investigates the relationship between loneliness and high-risk medication use in adults older than 65 years.
This cohort study uses Medicare data to measure and report low-value care use across and within individual health systems and identify system characteristics associated with higher use.
This cohort study examines outcomes associated with chronic kidney disease as defined by a fixed vs an age-adapted estimated glomerular filtration rate threshold.
This cohort study and meta-analysis examines differences by sex in US thyroid cancer incidence ratios compared with subclinical thyroid cancer rates at autopsy to understand more about gender inequities in thyroid cancer diagnosis.
This quality improvement study assesses the frequency of standardized screenings tied to performance metrics within a national network of federally qualified health centers.
This cross-sectional study evaluates the degree of anticoagulant use among nursing home residents with advanced dementia and atrial fibrillation at the end of life.
This cohort study examines use of preoperative testing before 3 low-risk ambulatory surgical procedures across diverse practice settings in Michigan.
This cohort study examines levels of glycemic control among nursing home residents with diabetes and compares rates of intensive glycemic control with high-risk antihyperglycemic agents across levels of cognitive impairment.
This open-label, multicenter, randomized clinical trial assesses whether providing relevant patient-managed web-based education in addition to usual care decreases the need for upper gastrointestinal tract endoscopic procedures vs usual care alone in patients with uninvestigated dyspepsia referred for endoscopy.
This quality improvement study uses data from medical intensive care units to investigate the association between time-limited trials and nonbeneficial treatments.
This survey study of physicians, nurse practitioners, and physician assistants explores practitioner understanding of diagnostic reasoning.
This cross-sectional study examines changes in the outpatient retail dispensing frequency of proposed treatments for coronavirus disease 2019 after the March 13, 2020, declaration of a national emergency due to the pandemic.
This cohort study uses data from the electronic health record of patients admitted to Cleveland Clinic Hospitals to assess the outcomes of adults with noncardiac inpatient admissions who were treated for hypertension.
This qualitative study of online vouchers for discounted DTC imaging services reveals consumerization of medicine and calls for regulations to balance convenience and cost with patient safety and physician oversight.
This meta-analysis assesses randomized clinical trials of statins to determine the time to benefit for prevention of a first major adverse cardiovascular event in adults aged 50 to 75 years.
This retrospective cohort study evaluates the effectiveness of early noninvasive cardiac testing in patients presenting to an emergency department with chest pain.
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