Explore the latest in acid base, electrolytes, and fluids, including metabolic and respiratory acidosis and alkalosis, hyperkalemia, and more.
This survey study investigates whether cannabis use is associated with risk of diabetic ketoacidosis in adults with type 1 diabetes.
This cohort study evaluated associations of increased creatinine levels, hyperkalemia, and continuation of therapy with the risk of emergency department visits, hospitalizations, and mortality within 1 year after initiation of renin angiotensin aldosterone system inhibitor (RAASI) therapy in patients with chronic kidney disease.
This randomized clinical trial evaluates the efficacy and safety of fludrocortisone in the treatment of cerebral salt wasting in patients with tuberculous meningitis.
In this Viewpoint, Roger I. Glass traces the discovery of the oral rehydration solution during a cholera epidemic in Bangladesh in the 1960s to treat severe diarrhea by promoting electrolyte balance and attributes oral rehydration therapy with saving hundreds of thousands of lives in the last 50 years.
This case report presents the electrocardiographic findings of a young woman with anorexia nervosa who had chest pain and persistent weight loss.
This systematic review and meta-analysis describes the methods to measure fluid balance, define fluid overload, and evaluate the association between fluid balance and outcomes in critically ill children.
This cohort study examines the morbidity in patients with peritoneal surface cancers who receive cytoreductive surgery with hyperthermic intraperitoneal chemotherapy.
This analysis evaluates the potential causal association between genetic variants related to elevated serum calcium levels and risk of coronary artery disease and myocardial infarction using mendelian randomization.
This case series study examines the myopathy, lactic acidosis, and sideroblastic anemia associated with YARS2-related mitochondrial disease.
A 77-year-old man presents with bowel obstruction, dehydration, a distended abdomen, and a colonic distension. What is your diagnosis?
This study examines the incidence of and risk factors for acute kidney injury among children with type 1 diabetes who are hospitalized for diabetic ketoacidosis.
This randomized clinical trial compares peritoneal dialysis and furosemide for prevention of fluid overload among infants who undergo cardiac surgery and are at high risk for acute kidney injury.
A young man had a significantly elevated calcium level, and imaging revealed a lesion in the location of the right inferior parathyroid gland and lytic bone lesions of the left mandibular ramus, left scapula, and C5 vertebra. What is your diagnosis?
This secondary analysis of a randomized clinical trial reports on whether the risk of hyperkalemia associated with use of mineralocorticoid receptor antagonists for patients with heart failure and reduced ejection fraction is reduced by sacubitril/valsartan in comparison with enalapril.
This systematic review and meta-analysis reports on the association between hydration status, the development and severity of hemolytic uremic syndrome, and the adverse outcomes of individuals infected with Shiga toxin–producing Escherichia coli.
A man had an elevated serum ionized calcium level; joint, back, and abdominal pain; constipation; fatigue; and depression; he underwent a parathyroid exploration and excision of a soft, ovoid tissue, believed to be a slightly enlarged left inferior parathyroid gland. What is your diagnosis?
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