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    Acute Kidney Injury

    Explore the latest in acute kidney injury, including advances in prevention, diagnosis, and management.

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    • Brugada Pattern, Tall Peaked T Waves, Absence of P Waves, and Broad QRS Complexes
      JAMA Internal Medicine
      Case Report
      March 27, 2023

      This case report presents the electrocardiogram findings of a patient in their 70s with chest tightness and shortness of breath for 5 hours and loss of consciousness for 10 minutes.

      Acid Base, Electrolytes, Fluids Cardiology Colorectal Cancer Gastrointestinal Cancer Nephrology
      Full Text | pdf link PDF | CME & MOC is active quiz
    • Computer-Estimated Heart Rate vs True Heart Rate—Be Aware of the Software
      JAMA Internal Medicine
      Case Report
      March 13, 2023

      This case report describes a patient in their 60s with gastrointestinal bleeding and shock with heart rate overcounting by software indicating severe hyperkalemia.

      Critical Care Medicine Emergency Medicine Challenges in Clinical Electrocardiography Resuscitation Acid Base, Electrolytes, Fluids
      Full Text | pdf link PDF | CME & MOC is active quiz
    • Sodium-Glucose Transport Protein 2 Inhibitor Use for Type 2 Diabetes and the Incidence of Acute Kidney Injury in Taiwan
      JAMA Network Open
      Research
      February 22, 2023

      This cohort study investigates the association of sodium-glucose transport protein 2 inhibitor (SGLT2i) use and the incidence of acute kidney injury (AKI) in patients with type 2 diabetes in Taiwan.

      Diabetes and Endocrinology Pharmacy and Clinical Pharmacology Clinical Pharmacy and Pharmacology Diabetes Adverse Drug Events
      Full Text | pdf link PDF open access
    • Association of Kidney Function With Development of Alzheimer Disease and Other Dementias and Dementia-Related Blood Biomarkers
      JAMA Network Open
      Research
      January 24, 2023

      This cohort study evaluates the association of kidney function with risk of diagnosis of incident Alzheimer disease or dementia and with the blood biomarkers neurofilament light, phosphorylated tau, and glial fibrillary acidic protein.

      Neurology Nephrology Chronic Kidney Disease Dementia and Cognitive Impairment
      Full Text | pdf link PDF open access
    • Neonatal Acute Kidney Injury Association With Mortality—Culprit, Innocent Bystander, or Canary in the Coal Mine?
      JAMA Network Open
      Opinion
      December 13, 2022
      Pediatrics Urology Critical Care Medicine Nephrology Neonatology
      Full Text | pdf link PDF open access
    • Frequency of Acute Kidney Injury and Association With Mortality Among Extremely Preterm Infants
      JAMA Network Open
      Research
      December 13, 2022

      This cohort study examines the frequency and markers of acute kidney injury in extremely low-birth-weight and extremely preterm infants.

      Pediatrics Neonatology Critical Care Medicine Urology Nephrology
      Full Text | pdf link PDF open access
    • The ATN Framework—Moving Preclinical Alzheimer Disease to Clinical Relevance
      JAMA Neurology
      Opinion
      October 1, 2022
      Dementia and Cognitive Impairment Neurology Nephrology
      Full Text | pdf link PDF
    • Highlights of Consensus-Based Recommendations for Acute Kidney Injury in Children
      JAMA Network Open
      Opinion
      September 30, 2022
      Pediatrics Consensus Statements Nephrology
      Full Text | pdf link PDF open access
    • Consensus-Based Recommendations on Priority Activities to Address Acute Kidney Injury in Children: A Modified Delphi Consensus Statement
      JAMA Network Open
      Review
      September 30, 2022

      This consensus statement identifies the work priorities across the pediatric acute kidney injury landscape of care, education, research, and advocacy.

      Pediatrics Consensus Statements Nephrology
      Full Text | pdf link PDF open access
    • Clinical Decision Support to Prevent Acute Kidney Injury After Cardiac Catheterization: Moving Beyond Process to Improving Clinical Outcomes
      JAMA
      Opinion
      September 6, 2022
      Cardiology Percutaneous Coronary Intervention Ischemic Heart Disease Health Care Quality Nephrology
      Full Text | pdf link PDF
    • Effect of Clinical Decision Support With Audit and Feedback on Prevention of Acute Kidney Injury in Patients Undergoing Coronary Angiography: A Randomized Clinical Trial
      JAMA
      Research
      September 6, 2022

      This cluster randomized clinical trial compares a multifaceted intervention for cardiologists in the prevention of acute kidney injury in patients undergoing coronary angiography or percutaneous coronary intervention vs usual practice.

      Clinical Decision Support Radiology Cardiology Cardiac Imaging Nephrology
      Full Text | pdf link PDF free
    • Complex Interaction of Lithium With Kidney and Bone Health
      JAMA Psychiatry
      Letter
      September 1, 2022
      Bipolar and Related Disorders Clinical Pharmacy and Pharmacology Nephrology Psychiatry and Behavioral Health Adverse Drug Events
      Full Text | pdf link PDF
    • Remdesivir in Patients With Severe Kidney Dysfunction: A Secondary Analysis of the CATCO Randomized Trial
      JAMA Network Open
      Research
      August 29, 2022

      This secondary analysis of a randomized clinical trial examines the risk of kidney or hepatic toxic effects among patients with impaired kidney function at baseline treated with remdesivir.

      Infectious Diseases Nephrology Pharmacy and Clinical Pharmacology Coronavirus (COVID-19) Chronic Kidney Disease
      Full Text | pdf link PDF | CME & MOC open access is active quiz
    • Sickle Cell Trait Associated With Kidney Failure and COVID-19 Death
      JAMA
      News
      August 2, 2022
      Coronavirus (COVID-19) Nephrology Sickle Cell Disease Hematology
      Full Text | pdf link PDF free
    • Association of Kidney Comorbidities and Acute Kidney Failure With Unfavorable Outcomes After COVID-19 in Individuals With the Sickle Cell Trait
      JAMA Internal Medicine
      Research
      August 1, 2022

      This genetic association study assesses the association of sickle cell trait with prepandemic health conditions in Million Veteran Program participants and assesses the severity and sequelae of COVID-19.

      Coronavirus (COVID-19) Nephrology Sickle Cell Disease Hematology
      Full Text | pdf link PDF | CME & MOC free is active quiz
    • Meta-analytic Techniques to Assess the Association Between N-acetylcysteine and Acute Kidney Injury After Contrast Administration: A Systematic Review and Meta-analysis
      JAMA Network Open
      Research
      July 5, 2022

      This systematic review and meta-analysis of N-acetylcysteine for the prevention of contrast-imaging acute kidney injury explores the heterogeneity, publication bias, and small study effect to determine the most suitable analytic method in a setting where the literature is contradictory.

      Nephrology Research, Methods, Statistics Radiology Medical Journals and Publishing
      Full Text | pdf link PDF open access
    • Development and Validation of a Personalized Model With Transfer Learning for Acute Kidney Injury Risk Estimation Using Electronic Health Records
      JAMA Network Open
      Research
      July 1, 2022

      This diagnostic study assesses the approaches to estimating acute kidney injury risk in hospitalized patients and proposes a novel model that uses machine learning.

      Health Informatics Nephrology Electronic Health Records
      Full Text | pdf link PDF open access
    • Acute Kidney Injury and the Field of Dreams—If We Predict It, Maybe They’ll Come
      JAMA Surgery
      Opinion
      June 1, 2022
      Cardiothoracic Surgery Nephrology Surgery Perioperative Care and Consultation
      Full Text | pdf link PDF
    • Utility of Biomarkers for Sepsis-Associated Acute Kidney Injury Staging
      JAMA Network Open
      Research
      May 18, 2022

      This cohort study examines associations between urinary levels of 2 cell-cycle arrest biomarkers and 30-day survival among patients with septic shock who developed acute kidney injury staged based on kidney function.

      Critical Care Medicine Pathology and Laboratory Medicine Urology Nephrology Resuscitation
      Full Text | pdf link PDF open access
    • APOL1 Risk Variants, Acute Kidney Injury, and Death in Participants With African Ancestry Hospitalized With COVID-19 From the Million Veteran Program
      JAMA Internal Medicine
      Research
      April 1, 2022

      This cohort study of US veterans hospitalized with COVID-19 with genetic information and with African ancestry through the VA Million Veteran Program to evaluates the association of APOL1 variations with.acute kidney injury

      Nephrology Equity, Diversity, and Inclusion Coronavirus (COVID-19) Genetics and Genomics Veterans Health
      Full Text | pdf link PDF | CME & MOC free is active quiz
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