Explore the latest in bipolar and related disorders, including recent advances in management of manic depression in children and adults.
This case-control study examines the real-time changes and associations between physical activity, sleep patterns, and energy and mood levels in people with and those without bipolar or depressive disorder.
This cohort study explores the association of polygenic risk scores for major depression, bipolar disorder, and schizophrenia with the risk for depression in the Danish population.
This study examines whether using aripiprazole for the first time or adding it to a treatment regimen lead to serious outcomes for patients with a history of taking antipsychotic medications.
This series of within-individual cohort studies assesses whether hydroxylmethyl glutaryl coenzyme A (HMG-CoA) reductase inhibitors, L-type calcium channel antagonists, and biguanides are associated with reduced rates of psychiatric hospitalization and self-harm in individuals with serious mental illness.
This Arts and Medicine essay reviews the 2 best graphic medicine publications of 2018: Ellen Forney’s Rock Steady, about her approach to self-managing her bipolar disorder, and Marnie Galloway’s Slightly Plural, about overcoming cultural myths of pregnancy and motherhood to develop one’s own story of parenting.
This cross-sectional, longitudinal study examines neuroimaging measures of emotion processing and regulation neural circuitries with symptoms of bipolar disorder in offspring of parents with bipolar disorder compared with offspring of parents with non–bipolar disroder psychopathologies and offspring of healthy parents.
This study uses normative modeling to map regional brain alterations to examine brain structural heterogeneity in adults with schizophrenia and bipolar disorder vs healthy individuals.
This population-based cohort study characterizes neurocognitive functions in 7-year-old children at familial high risk of schizophrenia and bipolar disorder in the Danish High Risk and Resilience Study VIA 7.
This Finnish nationwide cohort study examines the comparative effectiveness of pharmacologic treatments in the prevention of rehospitalization in a nationwide cohort of patients with bipolar disorder.
This Viewpoint argues that the therapeutic approach to bipolar disorder should mimic that for cancer, with immediate aggressive treatment and vigilant monitoring and follow-up to prevent long-term sequelae of disability, cognitive deficits, and suicide.
This randomized clinical trial evaluates the efficacy and safety of transcranial direct current stimulation as add-on therapy in patients with bipolar depression.
This study uses data from the population-based Generation R Study of Rotterdam, the Netherlands, to assess an association of genetic risk for schizophrenia and bipolar disorder with infant neuromotor development.
This genome-wide association study tests whether a polygenic score for schizophrenia is associated with treatment response to lithium in bipolar affective disorder and explores the potential molecular underpinnings of this association.
This case-control study examines the association between polygenic liability for schizophrenia and psychotic presentations of bipolar disorder.
This Viewpoint discusses a neurocomputational model of bipolar disorder and makes predictions about how mood changes will escalate, resolve, and reverse in bipolar disorder.
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