Explore the latest in stem cell transplantation, including recent advances in indications for the procedure, safer conditioning regimens, and more.
This randomized trial compares the effect of intensification of consolidation therapy using sequential or “tandem” vs single autologous transplant after induction therapy on event-free survival among children and young adults with high-risk neuroblastoma.
This Viewpoint summarizes recommendations from an International Society for Stem Cell Research task force charged with developing professional standards of patient consent for stem cell–based interventions offered outside a clinical trial given the spread of unregulated stem cell clinics offering unproven therapies.
This randomized trial compares the effects of 2 doses of nonlive adjuvanted recombinant zoster vaccine vs placebo on incidence of herpes zoster in adults who had undergone autologous hematopoietic stem cell transplantation.
This cohort study estimates the risk of 30-day hospital readmission among adults receiving autologous and allogenic hematopoietic cell transplants in the United States.
This study evaluates the interrater agreement and reliability of skin-specific and range of motion variables of the 2014 National Institutes of Health response criteria for patients with chronic graft-vs-host disease as well as a skin sclerosis grading scale.
This study describes the credentials and scope of training of physician and nonphysician practitioners working for US companies marketing unproven stem cell procedures.
This cohort study analyzes infants who received allogeneic hematopoietic cell transplants at age 12 months or younger to determine changes over time in complications and outcomes.
This consensus project reports the findings of the American Society for Blood and Marrow Transplantation, Center for International Blood and Marrow Transplant Research, and European Society for Blood and Marrow Transplantation expert panel, which convened to formulate consensus recommendations regarding the use of maintenance and/or consolidation therapies after autologous hematopoietic cell transplantation in patients with lymphoma.
This phase 2 clinical trial investigates whether injecting the myocardium of patients with heart failure with a high dose of mesenchymal precursor cells derived from bone marrow stem cells, compared with a sham injection, repairs myocardial damage enough to facilitate weaning from left ventricular assist devices (LVADs).
This cohort study examines patient data in the European Society for Blood and Marrow Transplantation Registry for causes of death, risk factors, and overall survival rates among patients who received a second cancer diagnosis after being treated with stem cell transplant.
This nonrandomized controlled intervention study compared the effect of matched sibling donor hematopoietic stem cell transplantation (HSCT) vs standard care comprising transfusions and hydroxyurea on transcranial Doppler velocities, a measure of cerebral vasculopathy, at 1 year in children with sickle cell anemia requiring chronic transfusion.
In this randomized trial, nonmyeloablative hematopoietic stem cell transplantation (HSCT) resulted in longer time to disease progression among patients with relapsing-remitting multiple sclerosis compared with continued disease-modifying therapy.
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