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    Breast Cancer

    Explore the latest in breast cancer, including recent guidelines and advances in screening, genetic testing, and precision treatment.

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    • Safety of Targeted Axillary Dissection After Neoadjuvant Therapy in Patients With Node-Positive Breast Cancer
      JAMA Surgery
      Research
      June 7, 2023

      This cohort study assesses 3-year clinical outcomes in patients with node-positive breast cancer who underwent targeted axillary dissection alone or in combination with axillary lymph node dissection.

      Oncology Surgery Surgical Oncology Women's Health
      Full Text | pdf link PDF
    • Cross-Sectional Analysis of Insurance Coverage for Lymphedema Treatments in the United States
      JAMA Surgery
      Research
      June 7, 2023

      This cross-sectional study analyzes health insurance coverage for lymphedema treatments from the top 3 insurance companies per state based on market share and enrollment data to determine individual access to pneumatic compression and surgical treatments across the United States.

      Health Care Economics, Insurance, Payment Women's Health Health Policy Physical Therapy Oncology
      Full Text | pdf link PDF
    • Evidence-Based De-Escalation in Axillary Management—Is Less Really More?
      JAMA Surgery
      Opinion
      June 7, 2023
      Women's Health Oncology Surgery Surgical Oncology
      Full Text | pdf link PDF
    • Outcomes of Different Quality of Life Assessment Modalities After Breast Cancer Therapy: A Network Meta-analysis
      JAMA Network Open
      Research
      June 6, 2023

      This network meta-analysis compares expert panel and computerized evaluation modalities with patient-reported outcome measures of aesthetic outcomes after surgical treatment among patients with breast cancer.

      Surgery Oncology Cancer Survivorship Women's Health Surgical Oncology
      Full Text | pdf link PDF open access
    • Pausing Endocrine Therapy for Pregnancy After Breast Cancer Found Safe
      JAMA
      News
      June 6, 2023
      Oncology Pregnancy Obstetrics Women's Health Obstetrics and Gynecology
      Full Text | pdf link PDF free
    • Germline Genetic Testing After Cancer Diagnosis
      JAMA
      Research
      June 5, 2023

      This observational study describes the prevalence of germline genetic testing in California and Georgia between 2013 and 2019 among patients diagnosed with cancer.

      Colorectal Cancer Endometrial Cancer Gastroenterology Gastrointestinal Cancer Cancer Genetics
      Full Text | pdf link PDF free
    • Association of Circulating Cardiomyocyte Cell-Free DNA With Cancer Therapy–Related Cardiac Dysfunction in Patients Undergoing Treatment for ERBB2 -Positive Breast Cancer
      JAMA Cardiology
      Research
      May 31, 2023

      This cohort study analyzes biomarker data for patients with ERBB2-positive breast cancer to determine the association between circulating cardiomyocyte cell-free DNA and subsequent cancer therapy–related cardiac dysfunction after anthracycline chemotherapy and ERBB2-targeted therapy.

      Cardiology Clinical Pharmacy and Pharmacology Adverse Drug Events Women's Health Oncology
      Full Text | pdf link PDF
    • Clinical Characteristics and Outcomes of Cancer Cases Among Syrian Refugees From Southern Turkey
      JAMA Network Open
      Research
      May 23, 2023

      This cross-sectional study examines the incidence and survival rates for Syrian adults and children with cancer residing in Turkey as refugees.

      Oncology Pediatric Cancer Global Health Violence Global Violence
      Full Text | pdf link PDF open access
    • Association of Allostatic Load With All-Cause Mortality in Patients With Breast Cancer
      JAMA Network Open
      Research
      May 18, 2023

      This cohort study evaluates the association of allostatic load with all-cause mortality in patients with breast cancer.

      Oncology Women's Health Health Policy Health Inequities Equity, Diversity, and Inclusion
      Full Text | pdf link PDF open access
    • A Letter to the Aunt I Never Met
      JAMA
      Opinion
      May 16, 2023

      In this narrative medicine essay, a family physician writes to her deceased aunt about how their shared genetics connects their histories through which she hopes to create a future unavailable to her aunt in the 1970s.

      Humanities Genetics and Genomics Narrative Medicine Cancer Genetics A Piece of My Mind
      Full Text | pdf link PDF
    • The After
      JAMA
      Opinion
      May 15, 2023

      In this narrative medicine essay, a family physician marks the moments of dread, fear, trauma, joy, and relief that began the day she was diagnosed with breast cancer to the more than 10 years of survival.

      Humanities Narrative Medicine Oncology Cancer Survivorship Women's Health
      Full Text | pdf link PDF free
    • Efficacy of Endocrine Therapy Plus Trastuzumab and Pertuzumab vs De-escalated Chemotherapy in Patients with Hormone Receptor–Positive/ ERBB2 -Positive Early Breast Cancer: The Neoadjuvant WSG-TP-II Randomized Clinical Trial
      JAMA Oncology
      Research
      May 11, 2023

      This randomized clinical trial aims to determine whether neoadjuvant de-escalated chemotherapy is superior to endocrine therapy, both in combination with pertuzumab and trastuzumab, in a highly heterogeneous hormone receptor–positive/ERBB2-positive early breast cancer.

      Cancer Biomarkers Genetics and Genomics Oncology Cancer Genetics Women's Health
      Full Text | pdf link PDF
    • Survival Outcomes in Patients With Hormone Receptor–Positive Metastatic Breast Cancer With Low or No ERBB2 Expression Treated With Targeted Therapies Plus Endocrine Therapy
      JAMA Network Open
      Research
      May 11, 2023

      This cohort study of women with hormone receptor–positive metastatic breast cancer treated with targeted therapy in combination with endocrine therapy compares the outcomes for those with low vs no ERBB2 expression.

      Oncology Cancer Genetics Cancer Biomarkers Targeted and Immune Cancer Therapy Genetics and Genomics
      Full Text | pdf link PDF open access
    • Treatment Disparities in Radiation and Hormone Therapy Among Women Covered by Medicaid vs Private Insurance in Cancer Registry and Claims Data
      JAMA Health Forum
      Research
      May 5, 2023

      This cohort study compares disparities in radiation and hormone therapy between women with breast cancer covered by Medicaid and those with private insurance using the Colorado Central Cancer Registry and data supplemented with All Payer Claims Data.

      Health Policy Health Care Economics, Insurance, Payment Women's Health Oncology Surgery
      Full Text | pdf link PDF open access
    • Adherence to Cancer Prevention Lifestyle Recommendations Before, During, and 2 Years After Treatment for High-risk Breast Cancer
      JAMA Network Open
      Research
      May 4, 2023

      This cohort study investigates whether adherence to overlapping cancer prevention lifestyle recommendations before, during, and after treatment was associated with recurrence or mortality among patients with high-risk breast cancer.

      Nutrition, Obesity, Exercise Oncology Cancer Survivorship Women's Health Lifestyle Behaviors
      Full Text | pdf link PDF open access
    • Bacterial Decolonization for Prevention of Radiation Dermatitis: A Randomized Clinical Trial
      JAMA Oncology
      Research
      May 4, 2023

      This randomized clinical trial determines the efficacy of bacterial decolonization to reduce the severity of acute radiation dermatitis compared with standard of care.

      Dermatology Oncology Radiation Oncology Women's Health Otolaryngology
      Full Text | pdf link PDF
    • Association of Staphylococcus aureus Colonization With Severity of Acute Radiation Dermatitis in Patients With Breast or Head and Neck Cancer
      JAMA Oncology
      Research
      May 4, 2023

      This cohort study assesses the association of Staphylococcus aureus colonization with acute dermatitis severity in patients with breast or head and neck cancer.

      Women's Health Pathology and Laboratory Medicine Radiation Oncology Oncology Infectious Diseases
      Full Text | pdf link PDF
    • Reexamining Time From Breast Cancer Diagnosis to Primary Breast Surgery
      JAMA Surgery
      Research
      May 1, 2023

      This case series investigates the association between time from breast cancer diagnosis to primary breast surgery and overall patient survival.

      Oncology Women's Health Surgery Surgical Oncology
      Full Text | pdf link PDF
    • Effect of Total Breast Reconstruction With Autologous Fat Transfer Using an Expansion Device vs Implants on Quality of Life Among Patients With Breast Cancer: A Randomized Clinical Trial
      JAMA Surgery
      Research
      May 1, 2023

      This randomized clinical trial of patients in the Netherlands who have undergone mastectomy compares self-reported quality of life among those receiving total breast reconstruction using autologous fat transfer with that among those receiving implant-based reconstruction.

      Oncology Women's Health Surgery Surgical Oncology
      Full Text | pdf link PDF has multimedia
    • Time to Surgery in Breast Cancer—Is Faster Always Better?
      JAMA Surgery
      Opinion
      May 1, 2023
      Oncology Surgery Surgical Oncology Women's Health
      Full Text | pdf link PDF
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