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    Child Development

    Explore the latest in child development, including etiologies and early detection of developmental delay, early interventions, and more.

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    • Sex-Specific Neurodevelopmental Outcomes Among Offspring of Mothers With SARS-CoV-2 Infection During Pregnancy
      JAMA Network Open
      Research
      March 23, 2023

      This cohort study examines the risk for neurodevelopmental disorders among male and female offspring exposed in utero to SARS-CoV-2 and whether pregnancy during the COVID-19 pandemic is associated with neurodevelopmental risk independent of SARS-CoV-2 exposure.

      Antenatal Exposures and Child Outcomes Coronavirus (COVID-19) Obstetrics and Gynecology Obstetrics Pregnancy
      Full Text | pdf link PDF open access
    • Trofinetide Receives FDA Approval as First Drug for Rett Syndrome
      JAMA
      News
      March 22, 2023
      Genetics and Genomics Neurogenetics Neurology Pediatrics
      Full Text | pdf link PDF free
    • Association of Hospital Resource Utilization With Neurodevelopmental Outcomes in Neonates With Hypoxic-Ischemic Encephalopathy
      JAMA Network Open
      Research
      March 21, 2023

      This cohort study examines whether there is an association between higher resource utilization during the first 4 days of age, quantified by hospital costs, and survival without neurodevelopmental impairment among infants with hypoxic-ischemic encephalopathy (HIE).

      Pediatrics Neurology Neonatology Psychiatry and Behavioral Health Child and Adolescent Psychiatry
      Full Text | pdf link PDF open access
    • Majority of Infant Formula Health Claims Are Poorly Supported
      JAMA
      News
      March 21, 2023
      Breastfeeding Neonatology Nutrition Pediatrics
      Full Text | pdf link PDF free
    • ADHD Drugs in Pregnancy Not Linked to Children’s Brain Development
      JAMA
      News
      March 21, 2023
      Pregnancy Antenatal Exposures and Child Outcomes Women's Health Psychiatry and Behavioral Health Child and Adolescent Psychiatry
      Full Text | pdf link PDF free
    • Let’s Stop Complaining That Early Childhood Assessments Do Not Predict IQ
      JAMA Pediatrics
      Opinion
      March 13, 2023

      This Viewpoint discusses the concern about the long-term predictive validity of early childhood development (ECD) assessments and how this concern reflects a misunderstanding of the constructs of ECD and intelligence, how they are assessed, and the myriad of other influences on the growth and trajectory of intellectual ability in children.

      Pediatrics
      Full Text | pdf link PDF
    • Identifying Replicable Subgroups in Neurodevelopmental Conditions Using Resting-State Functional Magnetic Resonance Imaging Data
      JAMA Network Open
      Research
      March 13, 2023

      This case-control study identifies subgroups of children with and without neurodevelopmental conditions with shared brain characteristics using functional magnetic resonance imaging (fMRI) data from 2 large, independent data sets.

      Psychiatry and Behavioral Health Child and Adolescent Psychiatry Radiology Neuroimaging Neurology
      Full Text | pdf link PDF open access
    • Predicting the Neurodevelopmental Outcome in Extremely Preterm Newborns Using a Multimodal Prognostic Model Including Brain Function Information
      JAMA Network Open
      Research
      March 8, 2023

      This prognostic study develops a multimodal model to predict the neurodevelopmental outcome of extreme preterm newborns at age 2 years.

      Pediatrics Neonatology Psychiatry and Behavioral Health Child and Adolescent Psychiatry
      Full Text | pdf link PDF open access
    • Finding Answers
      JAMA
      Opinion
      March 7, 2023

      In this narrative medicine essay, a pharmacoepidemiologist worries that her brother’s lifelong neurological challenges may have been caused by a heritable genetic variant and that she possibly passed it to her young son, who looks uncannily like his uncle.

      Humanities Genetics and Genomics Neurogenetics Neurology A Piece of My Mind
      Full Text | pdf link PDF
    • Association of Brain Microstructure and Functional Connectivity With Cognitive Outcomes and Postnatal Growth Among Early School–Aged Children Born With Extremely Low Birth Weight
      JAMA Network Open
      Research
      March 2, 2023

      This cohort study compares brain microstructure and functional connectivity strength with cognitive outcomes in association with postnatal growth among early school–aged children born preterm with extremely low birth weight.

      Pediatrics Neonatology Neurology
      Full Text | pdf link PDF open access
    • Telehealth Treatment of Behavior Problems in Young Children With Developmental Delay: A Randomized Clinical Trial
      JAMA Pediatrics
      Research
      March 1, 2023

      This randomized clinical trial investigates the effects of an internet-delivered parent-child interaction therapy for children aged 3 years with developmental delay.

      Pediatrics Health Care Delivery Models Mobile Health and Telemedicine
      Full Text | pdf link PDF
    • Is There Enough Choline for Children in Food Aid?
      JAMA Pediatrics
      Opinion
      March 1, 2023

      This Viewpoint discusses food insecurity and the importance of choline-fortified food aid products.

      Pediatrics Nutrition
      Full Text | pdf link PDF
    • Outdoor Play as a Mitigating Factor in the Association Between Screen Time for Young Children and Neurodevelopmental Outcomes
      JAMA Pediatrics
      Research
      March 1, 2023

      This cohort study analyzes data for young children to investigate the association of higher screen time with neurodevelopmental outcomes and whether this association is mediated by outdoor play.

      Media and Youth Pediatrics
      Full Text | pdf link PDF open access has multimedia
    • Associations Between Infant Screen Use, Electroencephalography Markers, and Cognitive Outcomes
      JAMA Pediatrics
      Research
      March 1, 2023

      This cohort study analyzes data for children from the population-based study Growing Up in Singapore Toward Healthy Outcomes (GUSTO) to examine the associations between infant screen time, electroencephalography markers, and school-age cognitive outcomes using a mediation analysis.

      Media and Youth Neurology Pediatrics
      Full Text | pdf link PDF open access
    • Dental Caries in Medicaid-Insured Preschool Children With or Without Special Health Care Needs in Northeast Ohio
      JAMA Network Open
      Research
      February 28, 2023

      This cross-sectional study uses data from Pediatric Providers Against Cavities in Children’s Teeth study to investigate caries experience, including untreated decay, among Medicaid-enrolled preschoolers with or without special health care needs.

      Pediatrics Dental Medicine
      Full Text | pdf link PDF open access
    • Sex Differences in Mental Health Problems and Psychiatric Hospitalization in Autistic Young Adults—Reply
      JAMA Psychiatry
      Letter
      February 22, 2023
      Autism Spectrum Disorders Pediatrics Psychiatry and Behavioral Health Child and Adolescent Psychiatry
      Full Text | pdf link PDF
    • Sex Differences in Mental Health Problems and Psychiatric Hospitalization in Autistic Young Adults
      JAMA Psychiatry
      Letter
      February 22, 2023
      Autism Spectrum Disorders Psychiatry and Behavioral Health Child and Adolescent Psychiatry
      Full Text | pdf link PDF
    • Measures of Brain Connectivity and Cognition by Sex in US Children
      JAMA Network Open
      Research
      February 21, 2023

      This cross-sectional study of US children aged 9 to 11 years assesses functional connectivity hubs displaying prominent sex differences and the association between global functional connectivity density and total cognitive scores.

      Pediatrics Neurology
      Full Text | pdf link PDF open access
    • Bidirectional Associations Between Adiposity and Cognitive Function and Mediation by Brain Morphology in the ABCD Study
      JAMA Network Open
      Research
      February 16, 2023

      This cohort study assesses bidirectional associations between adiposity and cognitive function in youth in the United States and tests mediational pathways through the lateral prefrontal cortext.

      Pediatrics Nutrition, Obesity, Exercise Obesity Neurology Adolescent Medicine
      Full Text | pdf link PDF open access
    • Trends in Screen Time Use Among Children During the COVID-19 Pandemic, July 2019 Through August 2021
      JAMA Network Open
      Research
      February 15, 2023

      This cohort study evaluates changes in children’s screen time from before the pandemic to during the pandemic, from July 2019 through August 2021.

      Pediatrics Media and Youth Coronavirus (COVID-19)
      Full Text | pdf link PDF open access
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