Explore the latest in colorectal cancer, including advances in the diagnosis, management, screening, and prevention of the disease.
This survey study assesses patient attitudes and preferences about cessation of low-value colorectal cancer screening and their overall comfort using age, life expectancy calculators, and colorectal cancer risk calculators in helping make individualized screening decisions.
This systematic review and meta-analysis examines interventions used to increase the rates of colorectal cancer screening tests.
This Markov model study assesses the cost-effectiveness of capecitabine and bevacizumab maintenance therapy after induction chemotherapy for treatment of metastatic colorectal cancer.
This multicenter, phase 2, single-arm trial assesses the activity of cetuximab plus irinotecan as third-line treatment for patients with RAS and BRAF wild-type metastatic colorectal cancer who were initially sensitive to and then resistant to first-line irinotecan- and cetuximab-based therapy.
This cohort study investigates possible mechanisms underlying primary resistance to immune checkpoint inhibitors of metastatic colorectal cancers displaying microsatellite instability or mismatch repair deficiency.
This cohort study uses propensity score matching analysis to compare outcomes of laparoscopic surgery with those of open surgery among patients with liver metastases from colorectal cancer.
This open-label, randomized phase 2 trial evaluates progression-free survival with chemotherapy plus bevacizumab vs cetuximab among patients with progression of metastatic colorectal cancer (mCRC) after bevacizumab plus chemotherapy.
This cohort study of women in the Nurses’ Health Study II assesses the association of obesity and weight gain since early adulthood with early-onset colorectal cancer.
This phase II feasibility study explores the long-term oncological outcomes and health-related quality of life of patients with cT1-3N0M0 rectal cancer who underwent neoadjuvant chemoradiotherapy followed by transanal endoscopic microsurgery.
This diagnostic study investigates whether nuclear ZEB2 expression in colorectal cancer is associated with early recurrence and reduced survival in 2 independent patient cohorts.
This population-based cohort study compares surgical outcomes of Dutch patients diagnosed as having colorectal cancer through the fecal immunochemical test–based screening program (screen-detected) and patients with non–screen-detected colorectal cancer.
This cross-sectional analysis of 71 articles discussing the ACOSOG Z6051 and ALaCaRT trials of laparoscopic vs open resection for rectal cancer evaluates the frequency of misinterpretation of these inconclusive trials and determines whether interpretations were concordant with the findings of the primary studies.
This cluster randomized clinical trial examines the effectiveness of implementing an electronic health record-embedded mailed fecal immunochemical test outreach program vs usual care for colorectal cancer screening among patients at community health centers.
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