Explore the latest in colorectal cancer, including advances in the diagnosis, management, screening, and prevention of the disease.
This randomized clinical trial examines the efficacy and toxic effects of postoperative capecitabine vs oxaliplatin plus capecitabine with radiotherapy for stage II and III rectal cancer.
This diagnostic study evaluates the accuracy and assessment time of an artificial intelligence (AI)–augmented digital system compared with standard microscopic assessment for interpretation of slides with colorectal polyp samples.
This secondary analysis of a randomized clinical trial investigates the treatment sequence for total neoadjuvant therapy of chemoradiotherapy followed by consolidation chemotherapy before total mesorectal excision surgery in patients with rectal cancer.
This cohort study uses data from the Health Professionals Follow-up Study, Nurses’ Health Study, and Nurses’ Health Study II to develop a dietary score that correlates with gut sulfur–metabolizing bacteria and to examine its association with colorectal cancer risk.
This cross-sectional study examines trends in the incidence of early-onset colorectal cancer among Black and White US residents aged 40 to 49 years.
This prognostic study develops and validates clinical calculators to predict recurrence-free survival and overall survival among patients with locally advanced rectal cancer treated with chemotherapy, radiotherapy, and surgery.
This systematic review summarizes the patient-reported factors associated with older adults’ decisions to continue screening for breast, prostate, colorectal, and cervical cancer.
This cross-sectional study evaluates the representation of racial and ethnic minority groups in breast, prostate, lung, and colorectal cancer studies with a focus on precision medicine objectives.
This Special Communication illustrates the consequences of not adjusting for left truncation and describes an approach to correct for length bias.
This cohort study assesses the rates and factors associated with outpatient low-value cancer screenings among nearly 6 million veterans who visited Veterans Health Administration primary clinics.
This randomized clinical trial determines the difference in 60-day mortality between patients randomized to systemic treatment only vs primary tumor resection followed by systemic treatment.
This randomized clinical trial investigates the use of a transanal drainage tube for the prevention of anastomotic leakage after laparoscopic low anterior resection in patients with rectal cancer.
This cross-sectional study compares the prevalence of breast and colorectal cancer screening adherence and identifies factors associated with screening adherence among women residing in rural vs urban areas.
This phase 2 clinical trial examines the effect of cetuximab plus avelumab as a rechallenge strategy in patients with RAS wild-type metastatic colorectal cancer.
This cohort study investigates the association of delayed surgery with oncologic long-term outcomes in patients with nonresponsive locally advanced rectal cancer.
This cohort study evaluates stage at diagnosis among patients with gastrointestinal cancer in Japan before and during the COVID-19 pandemic.
This cross-sectional study compares current rates of prescription of fluorouracil, folinic acid, oxaliplatin, and irinotecan plus bevacizumab (FOLFOXIRI-B) with rates from 2015 to 2018 and assesses Dutch medical oncologists’ perspectives on treatment with FOLFOXIRI-B.
This economic evaluation analyzes the cost-effectiveness of screening and prevention strategies by genotype among women with Lynch syndrome.
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