Explore the latest in colorectal cancer, including advances in the diagnosis, management, screening, and prevention of the disease.
This randomized crossover trial evaluates the effectiveness of fluoropyrimidine-based systemic chemotherapy in patients with inoperable low-grade mucinous appendiceal adenocarcinoma.
This randomized clinical trial assesses progression-free survival among patients with RAS wild-type metastatic colorectal cancer receiving panitumumab plus standard-of-care trifluridine-tipiracil as third-line therapy.
This cohort study assesses quality of life and functional outcome of patients with rectal cancer who are followed up via a watch-and-wait approach.
This cohort study examines the association of estimated life expectancy with colonoscopy findings and recommendations for surveillance colonoscopy among adults older than 65 years in New Hampshire.
This case report presents the electrocardiogram findings of a patient in their 70s with chest tightness and shortness of breath for 5 hours and loss of consciousness for 10 minutes.
This nonrandomized clinical trial assesses the recommended phase 2 dose of regorafenib, ipilimumab, and nivolumab immunotherapy for patients with refractory microsatellite stable metastatic colorectal cancer.
This randomized clinical trial assesses whether 2 tailored interventions delivered remotely were effective at increasing the rate of any or all needed cancer screenings in rural women.
This cross-sectional study compares rates of molecular testing and targeted therapy among patients with non–small cell lung cancer (NSCLC) and colorectal cancer (CRC) use by practice type and across practices.
This case-control study conducted in Sweden examines the association between birth by cesarean delivery and development of early-onset colorectal cancer before age 50 years.
This phase 3 randomized clinical trial assesses locoregional control rates after hyperthermic intraperitoneal chemotherapy with mitomycin C during cytoreductive surgery among adults with locally advanced colorectal cancer in Spain.
This cohort study evaluates the cancer spectrum and risks in children and adults with germline PTEN variants.
This case-control study examines how recent weight loss of patients with colorectal cancer may affect estimates of the association of colorectal cancer risk with overweight or obesity.
This cohort study investigates the effectiveness of circulating tumor DNA methylation in early detection of colorectal cancer recurrence.
This randomized clinical trial assesses the effect of adding panitumumab vs bevacizumab to standard first-line chemotherapy on overall survival among patients with RAS wild-type, left-sided, metastatic colorectal cancer.
This cohort study examines all-cause and cancer-specific mortality among patients in the Veterans Affairs health system whose colorectal cancer was not detected by colonoscopy.
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