Explore the latest in critical care medicine, including management of respiratory failure, sepsis, HAI prevention, end-of-life care, and more.
This quality improvement study reports the outcome associated with implementing a multidisciplinary apparent cause analysis, daily discussion of extubation readiness, and daily discussion of fluid balance goals in hospital intensive care units.
This Viewpoint summarizes the major issues that led to the decision to draft a revision of the Uniform Determination of Death Act, the alternatives that were considered, why there was failure to reach consensus, and what this means for the future.
A patient in his mid-60s underwent bilateral orthotopic lung transplant and is later hospitalized for sepsis from pneumonia complicated by acute transplant rejection, without any cardiac symptoms. He develops severe acute respiratory distress syndrome requiring intubation and paralysis. Electrocardiography shows sudden ST-segment changes. What would you do next?
This case series study examines the clinical evidence cited for US Food and Drug Administration–approved clinical decision support devices for use in the critical care setting.
This cross-sectional study examines COVID-19 hospital admissions and changes in inpatient and intensive care unit (ICU) occupancy for different US states and time periods during 2020.
This cross-sectional study examines antibiotic exposure, days of therapy, types of antibiotics, and changes in use patterns among newborns in neonatal intensive care units (NICUs) across the US from 2009 to 2021.
This randomized trial assesses whether prone vs supine positioning decreases the time to successful weaning of extracorporeal membrane oxygenation (ECMO) in patients with severe acute respiratory distress syndrome (ARDS).
This clinical trial compares the efficacy of intubation withholding vs routine practice on clinical outcomes of comatose patients with acute poisoning and a Glasgow Coma Scale score less than 9.
This Arts and Medicine feature reviews The Autumn Ghost, an historical retelling of the 1952 polio epidemic in Copenhagen, Denmark, which catalyzed developments in anesthesia and respiratory support procedures that are still in use today.
This randomized clinical trial compares the efficacy of sighs in addition to usual care vs usual care alone in improving clinical outcomes among trauma patients receiving mechanical ventilation and are at risk for developing acute respiratory distress syndrome.
In this Medical News article, Johns Hopkins University computer scientist Suchi Saria, PhD, MSc, discusses the use of AI tools in early sepsis detection and other clinical applications.
In this narrative medicine essay, a retired family physician recalls sitting with her mother in the final minutes of her life after the ventilator has been removed.
Red blood cell transfusion threshold guidelines from the AABB transfusion medicine association have been updated to incorporate an expanded evidence base and to introduce guidance specific to children.
This cluster randomized trial compares use of standard- vs small-volume blood collection tubes in decreasing rates of anemia and red blood cell transfusions among patients treated in intensive care units.
This cohort study evaluates and describes red blood cell transfusion practices in intensive care units worldwide.
This JAMA Insights summarizes best clinical practices for use of whole blood, plasma, cryoprecipitate, platelets, and red blood cells in the process of blood transfusion.
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