Explore the latest in critical care medicine from The JAMA Network, including management of respiratory failure, sepsis, HAI prevention, end-of-life care, and more.
A woman presented with constant right-sided nasal obstruction; computed tomographic scan showed complete opacification of the right paranasal sinuses with mass effect on the medial maxillary wall with mild hyperostosis posterolaterally. What is your diagnosis?
This cohort study compares estimates of sepsis incidence, outcomes, and trends based on clinical data from US hospital electronic health record systems vs claims-based ICD-9 data.
This randomized clinical trial compares the effects of an early resuscitation sepsis protocol (administration of intravenous fluids, vasopressors, and blood transfusion) vs usual care for prevention of in-hospital mortality among adults with sepsis and hypotension in Zambia.
This population-based cohort study characterizes the intensity of care and locations of death of immigrants in the last 6 months of their life in Ontario, Canada.
This cohort study assesses the validity of a pediatric version of the Sequential Organ Failure Assessment (SOFA) scoring system compared with the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3) to examine the in-hospital mortality of critically ill children with confirmed or suspected infection and sepsis.
This cohort study examines the association of evidence-based care processes in routine care for Staphylococcus aureus bacteremia with mortality at Veterans Health Administration hospitals.
This study examines the electronic health records of healthy adolescents who presented with signs and symptoms of sepsis to 12 community hospital emergency departments in southwestern Pennsylvania.
This randomized trial compares the effect of a program to promote systematic intensive care unit (ICU) admission vs standard practice on 6-month mortality in critically ill elderly patients.
This randomized trial compares the effects of ventilator lung recruitment using PEEP titration vs a conventional low-PEEP strategy on 28-day mortality in patients with moderate to severe acute respiratory distress syndrome (ARDS).
This randomized clinical trial compares the effects of an individualized blood pressure management strategy vs standard blood pressure management strategy on postoperative organ dysfunction among high-risk patients undergoing major surgery.
This Viewpoint summarizes recommendations from a specialist roundtable meeting about requirements for and appropriate use of extracorpeal organ support for patients with critical illness or organ failure.
This narrative review summarizes recent advances in the prevention, diagnosis, and treatment of delirium and highlights critical areas for future research.
This cohort study estimates the accuracy of individual complete blood cell count parameters to identify febrile infants with invasive bacterial infections.
This Viewpoint discusses Nevada’s revisions to its Uniform Determination of Death Act and the rationales behind them.