Explore the latest in dementia and cognitive impairment, including advances in diagnosis, management, and prevention of the disorders.
This case study investigates the association of regional in vivo retention of the tau positron emission tomography ligand [18F]flortaucipir with the density of tau neuropathology in the corresponding brain regions in a patient with early-onset Alzheimer disease caused by a PSEN1 mutation.
This case-control study investigates cerebrospinal fluid levels of neurofilament light protein in participants with various forms of dementia, motor neuron disease, and movement disorders and controls, as determined by clinical and autopsy-definite criteria.
This case series details 3 cases of a communication barrier called binary reversals in patients with the nonfluent-agramatic variant of primary progressive aphasia.
This study uses telephone interviews of patients and their surrogates to evaluate surrogates’ knowledge of patients’ treatment goals and confidence in their ability to make patients’ treatment decisions.
This personal narrative examines the sudden end of an ill spouse’s medical career through the metaphor of a surfing mishap.
This pilot study assesses the accuracy of predictions made in 2001 by expert clinicians and researchers on technologic innovations in therapy for Alzheimer disease and cardiovascular disease by 2021.
This study examines the association of dementia with mortality and examines factors associated with dementia predictors in adults with Down syndrome.
This Medical News article discusses a recently discovered association between time of year and cognitive performance even in people with Alzheimer disease.
This population-based study examines the association of cerebrospinal fluid neurofilament light protein and neurogranin levels with the risk of mild cognitive impairment among participants in the Mayo Clinic Study of Aging.
This randomized clinical trial examines the effect of an exercise intervention on the functional levels of elderly patients hospitalized for acute care.
This cohort study assesses the association of haptoglobin genotypes with cognitive function and decline in elderly African American adults with type 2 diabetes.
This population-based, cross-sectional study explores the association between the peripapillary retinal nerve fiber layer thickness and brain alterations in the visual and limbic networks in elderly people without dementia.
This population-based study characterized patients with professional guardians using records from the Department of Veterans Affairs health care system.
This meta-analysis investigates whether concomitant use of cholinesterase inhibitors or memantine affect cognitive outcomes in Alzheimer disease (AD) clinical trials.
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