Explore the latest in cutaneous drug reactions, including advances in understanding the mechanisms and genetics of adverse events.
This Delphi consensus exercise with more than 50 dermatology experts explores the need for a skin-directed epidermal necrolysis assessment tool that incorporates disease morphologic traits, terminology, and sites of involvement.
This retrospective cohort study evaluated the outcomes of administering plasmapheresis or intravenous immunoglobulin therapy first after ineffective systemic corticosteroid treatment among inpatients with Stevens-Johnson syndrome and toxic epidermal necrolysis in Japan.
A 75-year-old man with myelodysplastic syndrome that has been well controlled with lenalidomide develops multiple nonhealing cutaneous ulcers. What is your diagnosis?
This case series characterizes the clinical features and the clinical time course of TNF inhibitor–induced psoriasiform eruptions in children.
This systematic review and meta-analysis of 38 studies including 2917 patients evaluates the prevalence of antibiotics associated with Stevens-Johnson syndrome and toxic epidermal necrolysis worldwide.
This analysis of pooled data from 3 randomized clinical trials evaluates the association between immune-related adverse events and atezolizumab efficacy in patients with advanced non–small cell lung cancer.
A 56-year-old woman with metastatic hormone receptor–positive, ERBB2-negative breast cancer presents with pruritic, erythematous, scaly macules and papules on her forearms, faces, chest, and upper back. What is your diagnosis?
A woman in her 80s initially presented with numerous, primarily photodistributed, crusted, and ulcerated plaques of the trunk and extremities and a medical history of essential thrombocytosis treated with hydroxyurea for 14 years. What is your diagnosis?
This Patient Page describes the symptoms, diagnosis, and treatment of drug reaction with eosinophilia and systemic symptoms.
This retrospective cohort study examines the association of lymphocyte and neutrophil levels with treatment outcomes in 147 patients with epidermal necrolysis in France.
This case series describes the outcome of high-dose vitamin D treatment in 6 inpatients with acute skin injury.
This retrospective case series study of 7 patients describes the characteristic symptoms of a potentially life-threatening hypersensitivity reaction to trimethoprim-sulfamethoxazole SCoRCH, or sudden conjunctivitis, lymphopenia, and rash combined with hemodynamic changes.
This case series describes the development of morbilliform drug eruption after breast surgery.
This case report describes a 78-year old woman with a stage IIA BRAF wild-type melanoma on the left leg who experienced a grade 2 vitiligo, a marked skin thickening, and painful swelling of the limbs.
This case series describes the clinicopathological features and treatment response of acneiform eruptions following elexacaftor-tezacaftor-ivacaftor treatment in patients with cystic fibrosis.
This case series describes the different dermatologic adverse events that patients experienced while using amivantamab.
This cross-sectional study of DRESS syndrome cases creates a model capable of predicting recurrence to identify patients most at risk.
This clinical evidence synopsis summarizes a Cochrane review on the use of systemic immunomodulatory therapies to decrease mortality rates in Stevens-Johnson syndrome/toxic epidermal necrolysis.
This case-control study uses single-institution data to explore risk factors associated with vancomycin drug reaction with eosinophilia and systemic systems (DRESS) syndrome.
This systematic review with meta-analysis examines the incidence of phosphoinositide 3-kinase inhibitor–associated cutaneous adverse events in patients with cancer.
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