Explore the latest in clinical pharmacy and pharmacology, including topics in drug safety, development, pharmacogenetics, and pharmacoeconomics.
This cohort study examines survival among patients receiving antibiotic therapy concurrent with chemotherapy with gemcitabine or fluorouracil for metastatic pancreatic ductal adenocarcinoma.
This cross-sectional study evaluates statin use for primary prevention of atherosclerotic cardiovascular disease in the US by 10-year risk and by race and ethnicity.
This cohort study uses data from Medicare fee-for-service and a commercial insurance database to evaluate prescribing patterns of oral anticoagulants for patients with venous thromboembolism and identify clinical events that precede treatment changes.
This platform randomized clinical trial examines the effectiveness of ivermectin at a targeted dose of 600 μg/kg daily compared with placebo for the treatment of early mild to moderate COVID-19.
This Medical News article discusses research presented at the American College of Cardiology and World Congress of Cardiology conference this March.
This decision analytical model study assesses projections of simulated effects of Paxlovid rollout on hospitalizations and mortality using 10 models.
This cross-sectional study examines how key demographic and predisposing factors are associated with consumer trust in pharmaceutical manufacturers.
This cross-sectional study explores the health-related values and preferences of adults who had been preterm infants and parents of preterm infants concerning the use of cyclo-oxygenase inhibitors in preterm infants to prevent patent ductus arteriosus–related morbidity and mortality.
This retrospective cohort study evaluated the outcomes of administering plasmapheresis or intravenous immunoglobulin therapy first after ineffective systemic corticosteroid treatment among inpatients with Stevens-Johnson syndrome and toxic epidermal necrolysis in Japan.
This cohort study examines the association of the use of leukotriene-receptor antagonists during pregnancy with the risk of neuropsychiatric events in offspring.
This cluster randomized clinical trial assesses the effect of a coordinated, multifaceted intervention of assessment, education, and feedback vs usual care on the prescribing of all 3 groups of recommended therapies (high-intensity statins, angiotensin-converting enzyme inhibitors or angiotensin receptor blockers, and sodium-glucose cotransporter 2 inhibitors and/or glucagon-like peptide 1 receptor agonists) for adults with type 2 diabetes and atherosclerotic cardiovascular disease.
This randomized clinical trial compares the efficacy of a treat-to-target low-density lipoprotein cholesterol (LDL-C) strategy of 50 to 70 mg/dL as the goal vs high-intensity statin therapy for the 3-year composite of death, myocardial infarction, stroke, or coronary revascularization in patients with coronary artery disease.
A 72-year-old man presented with right eye conjunctival injection, chemosis, eyelid edema, and pain with eye movements. Examination of the right eye was notable for visual acuity of 20/50, reduced ocular motility in all gazes, proptosis, and chemosis. Treatment with vancomycin and ceftriaxone and ampicillin-sulbactam was followed by a worsening in symptoms. What would you do next?
This JAMA Forum discusses implementation of the Medicare drug pricing provision of the Inflation Reduction Act of 2022 and ways the new frameworks can be tweaked to achieve the desired public health goals.
This Medical News Q&A discusses research highlights from the recent Conference on Retroviruses and Opportunistic Infections.
This study compares expenditures for diabetes medications before and after metabolic surgery among patients with diabetes in Michigan.
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