Explore the latest in clinical pharmacy and pharmacology, including topics in drug safety, development, pharmacogenetics, and pharmacoeconomics.
This quality improvement study examines trends in pharmacy closures in the United States between 2009 and 2015, as well as pharmacy, community, and market factors that might be associated with such closures.
This systematic review and meta-analysis examines the risk for serious infections, opportunistic infections, and cancers in individuals receiving interleukin inhibitor therapies for rheumatologic diseases.
This cohort study examines the association between use of 5α-reductase inhibitors and prostate cancer mortality among US Medicare beneficiaries.
This JAMA Women’s Health summarizes evidence-based use of bisphosphonates for fracture prevention in women with postmenopausal osteoporosis, and reviews potential harms of the drugs and alternative agents (denosumab, raloxifene) for patients with contraindications or intolerance to alendronate, risedronate, or zoledronate.
This Viewpoint argues that using a pack-splitting strategy for dispensing drugs that are sold in blister card packages can yield substantial cost savings for some expensive drugs.
This cluster randomized clinical trial investigates the effect of clinical geriatric assessments and collaborative medication reviews by geriatrician and family physician on health-related quality of life and other patient-relevant outcomes in home-dwelling older patients receiving polypharmacy.
This population-based case-control study of individuals aged 66 years and older in Ontario, Canada, examines whether angiotensin receptor blockers are associated with a higher risk of suicide than angiotensin-converting enzyme inhibitors.
This cross-sectional study describes the characteristics of abbreviated new drug applications approved by the US Food and Drug Administration, focusing on those with limited generic competition or with history of shortages.
This secondary analysis of a randomized clinical trial investigates outcomes 1 year after cessation of the SCORE2 treatment schedule (24 months after randomization) in patients treated with anti–vascular endothelial growth factor (anti-VEGF) therapy for macular edema due to central retinal or hemiretinal vein occlusion.
This cohort study investigates the prevalence and cost of overpayments for topical dermatologic prescription drugs.
This article discusses the currently available treatments for depression in bipolar disorder and summarizes best practices for treatment.
This randomized clinical trial examines whether providing essential medicines at no charge to outpatients who reported not being able to afford medicines improves treatment adherence.
This study compares the sensitivity, specificity, and estimated number needed to treat to prevent 1 atherosclerotic cardiovascular disease event in 10 years according to statin criteria from 5 major guidelines.
This economic evaluation examines whether pharmaceutical industry payments to gastroenterologists are associated with how often they prescribe the pharmaceuticals’ drugs for inflammatory bowel disease.
This cross-sectional study uses Centers for Medicare & Medicaid Services data to evaluate the association between industry payments to physicians who prescribe gabapentinoids and gabapentinoid prescribing behavior.
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