Explore the latest in clinical pharmacy and pharmacology from The JAMA Network, including topics in drug safety, development, pharmacogenetics, and pharmacoeconomics.
This pooled analysis of phase 3 trials evaluates the efficacy of deoxycholic acid injection compared with submental liposuction among patients with submental liposis.
This Medical News article examines the use of stomach acid suppressors to treat mild gastric reflux in infants.
This study examines assesses inappropriate antibiotic prescribing 12 months after stopping a randomized clinical trial of a behavioral intervention intended to reduce the rate of inappropriate antibiotic prescribing for acute respiratory infections.
This cohort study uses data from the Taiwan National Health Insurance database to assess the association between use of non–vitamin K oral anticoagulants with vs without concurrent medications and risk of major bleeding in patients with nonvalvular atrial fibrillation.
This Clinical Evidence Synopsis summarizes a Cochrane review on the efficacy of long-acting β-agonists (LABAs) combined with long-acting muscarinic antagonists vs LABAs combined with inhaled corticosteroids for patients with stable chronic obstructive pulmonary disease.
This population-based cohort study examines the association of maternal antidepressant medication use during pregnancy with intellectual disability in offspring and investigates the importance of parental mental illness for such an association.
This population-based, case series study examines the incidence of suicide attempts during treatment with methylphenidate in patients with attention-deficit/hyperactivity disorder.
This systematic review and meta-analysis examines the responses of children and adolescents with common psychiatric disorders who receive selective serotonin reuptake inhibitors, serotonin-norepinephrine reuptake inhibitors, or placebo.
A 15-year-old boy presented to a hospital with pain and purpura of his left thigh after an intramuscular injection. What is your diagnosis?
This study assesses the association of dissemination of an educational document about the lack of efficacy of docusate with docusate administration and whether changes in docusate administration were associated with changes in the administration of comparable laxatives.
This cross-sectional analysis of trial documents submitted to regulators examines the degree to which the study purpose is explained to potential participants in randomized clinical trials of antibiotics.
This study examines PCSK9i cost-sharing requirements for Medicare Part D plans nationwide, which insure 41 million beneficiaries.
This study evaluates the cost-effectiveness of evolocumab in patients with atherosclerotic cardiovascular disease when added to standard background therapy.
This Viewpoint promotes using outcomes-based pricing strategies for proprotein convertase subtilisin/kexin type 9 inhibitors.
This case series investigates whether low-dose naltrexone is an effective treatment for recalcitrant Hailey-Hailey disease.
This cohort study investigates the frequency, clinical spectrum, and optimum treatment approach to neurological complications associated with anti–PD-1 inhibitor use.