Explore the latest in clinical pharmacy and pharmacology, including topics in drug safety, development, pharmacogenetics, and pharmacoeconomics.
This randomized clinical trial tests the efficacy of patient activation interventions with or without financial incentives to promote prescribing of thiazide diuretics in patients with hypertension and improve the quality of hypertension management.
This study examines the FDA Adverse Event Reporting System and PubMed databases for cases of noninfectious pneumonia acquired after FDA approval of the drug ustekinumab.
This cohort study assesses self-reported quality of life among patients referred to oncodermatology clinics for pruritus associated with immunotherapy.
This cohort study of Tennessee Medicaid enrollees from 1999 through 2014 investigates the risk of unexpected death among children and youths aged 5 through 24 years without psychosis who are new users of antipsychotic medications compared with new users of control medications.
This study evaluates the interindividual variability in low-density lipoprotein cholesterol reduction with the PCSK9 inhibitor drug evolocumab.
This analysis uses hospital billing databases of inpatient discharges to compare antibiotic prescribing for community-acquired pneumonia by hospital type.
This cohort study evaluates the association of adherence and treatment intensity with cardiovascular outcomes in patients with documented cardiovascular disease, type 2 diabetes without cardiovascular disease or chronic kidney disease, and chronic kidney disease without cardiovascular disease.
This systematic review and meta-analysis examines randomized clinical trials (RCTs) of modern cancer drugs in the adjuvant setting to determine the incidence of severe adverse events reported in placebo groups.
This secondary analysis of a randomized clinical trial examines the association of modern chemoradiotherapy with survival among patients with stage I to II small cell lung cancer compared with that among patients with stage III small cell lung cancer.
This case report describes cyclosporine-induced gingival hypertrophy in a child with aplastic anemia.
This national survey study uses US Census Bureau data to estimate the proportion of non–US-born and noncitizen health care professionals in the United States in 2016.
This cohort study uses registry and Medicare claims data to investigate associations between prescription for a renin-angiotensin system (RAS) inhibitor at hospital discharge after transcatheter aortic valve replacement (TAVR) and 1-year all-cause mortality and heart failure readmissions.
This survey study examines the association of higher insulin costs with nonadherence in patients with diabetes.
This Viewpoint discusses obstacles that limit the use of biosimilar filgrastim in the United States compared with countries in the European Union and Japan and discusses strategies that might help biosimilar filgrastim use become more widespread.
This study examines the presence and extent of undeclared financial conflicts of interest among authors of clinical practice guidelines related to high-revenue medications.
This cohort study uses electronic health record data from the Clinical Practice Research Datalink database to examine the association between antihypertensive treatment prescriptions and all-cause mortality, cardiovascular disease, and adverse events in low-risk patients with mild hypertension.
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