Explore the latest in endocrinology from The JAMA Network, including advances in management of diabetes, thyroid disorders, and other common endocrine diseases.
A man in his 60s presented with severe fatigue, and his medical history was notable for primary hyperparathyroidism 6 years prior to presentation, for which the patient refused therapeutic management; examination revealed a large tumor on the distal part of the right fourth finger. What is your diagnosis?
A woman in her 50s with a history of systemic lupus erythematosus, congestive heart failure, and diabetes presents to the emergency department with worsening abdominal pain and a 4-day history of progressively worsening abdominal pain and diarrhea. What is your diagnosis?
This Clinical Evidence Synopsis summarizes a Cochrane review on the effects of adding oral hypoglycemic agents to insulin for patients with type 2 diabetes mellitus who have not achieved optimal glycemic control with insulin alone.
This phase 2 randomized trial compared the effects on hemoglobin A1c levels of varying doses of oral once-daily semaglutide vs placebo vs subcutaneous semaglutide in patients with type 2 diabetes.
This JAMA Clinical Guidelines Synopsis summarizes the 2017 Endocrine Society clinical practice guideline on endocrine treatment of gender-dysphoric/gender-incongruent persons.
This cohort simulation model evaluates the use of tests and treatment of latent tuberculosis infection in residents born outside the United States.
This cohort study of US women participating in the Nurses’ Health Study II prospectively evaluates the association of a history of gestational diabetes with incident cardiovascular risk.
This study evaluates the relationship between bone mineral density and intracranial aneurysm.
This cohort study uses Medicaid claims data to assess the association between antidepressant use and the risk of incident type 2 diabetes among youths by antidepressant subclass and duration of use, cumulative dose, and average daily dose.
This cross-sectional analysis of Medicaid data examines variability across US regions for rates of thyroid surgery among Medicaid beneficiaries.
This population-based cohort study compares rates of severe hypoglycemia and diabetic ketoacidosis among children, adolescents, and young adults with type 1 diabetes managed with insulin pump therapy vs insulin injection therapy.
This JAMA Clinical Guidelines Synopsis summarizes the 2016 practice guideline on management of diabetic foot sponsored by the Society for Vascular Surgery in collaboration with the American Podiatric Medical Association and the Society for Vascular Medicine.
This cohort study tests the association between early-life antibiotic use and islet or celiac disease autoimmunity in genetically at-risk children prospectively followed up for type 1 diabetes or celiac disease.
This study develops and validates a risk stratification tool to categorize risk of future hypoglycemia-related emergency department or hospital use in patients with type 2 diabetes.
This cohort study examines the probability, rate, and magnitude of tumor growth in patients with papillary thyroid cancer during active surveillance.
This cohort study determines the frequency of thyroid carcinoma in Brazilians with Li Fraumeni syndrome who are carriers of a founder TP53 p.R337H mutation.
This systematic review and meta-analysis compares the incidence and risk of endocrine adverse events following treatment with US Food and Drug Administration-approved immune checkpoint inhibitor regimens.