Explore the latest in epilepsy and seizures, including the epidemiology, etiology, diagnosis and management of seizure disorders.
This Viewpoint describes the neurological disorder known as psychogenic nonepileptic attacks (PNEA)—including the symptoms, appropriate diagnostic testing, and treatment with cognitive behavioral therapy—and how it can be distinguished from epilepsy to avoid treating patients with PNEA with potentially harmful epileptic medications or surgery.
This case series study assesses the potential role of febrile seizures and other risk factors associated with sudden death in childhood and describes the epidemiology, mechanisms, and prevention of sudden death in childhood.
This review of electrocorticographic recordings and clinical meta-data assesses seizure control in 12 patients with focal epilepsy who were treated with closed-loop invasive brain stimulation.
This case series evaluates an exome-based gene panel approach to maximize diagnostic yield for children with idiopathic epilepsy.
This case report describes an infant who presented with intrauterine growth retardation, retarded psychomotor development, and seizures. The patient was diagnosed as having Coats-plus syndrome.
This cohort study examines the association of seizure spread with seizure recurrence after surgery in patients who underwent medial temporal resections for drug-resistant temporal lobe epilepsy.
A man in his 60s presents to an epilepsy monitoring unit with transient episodes of expressive speech difficulties, paroxysmal dizziness, and involuntary nonsuppressible jerks of the right arm that begin without warning. What is your diagnosis?
This open cohort study derives prediction models to estimate the risk of psychiatric adverse effects from levetiracetam use in patients with epilepsy.
This cohort study examines the use of antiepileptic drugs and differences between valproate and topiramate prescribing in women of childbearing age with epilepsy.
This study reviews protocols for treating convulsive status epilepticus from 33 emergency medical services systems in California to determine if they had incorporated updated evidence-based guidelines.
This multicenter cohort study assesses outcomes of piriform cortex resection among patients with temporal lobe epilepsy.
This comparative analysis assesses the efficacy, procedural morbidity, and epilepsy outcomes of 2 patient populations undergoing stereoelectroencephalography vs subdural electrode implantation for evaluation of intractable epilepsy.
This study uses exome sequencing and genetic evaluation to explain the shared condition of 4 children from 2 unrelated families who were affected by refractory epileptic seizures, respiratory failure, brain abnormalities, and death in the neonatal period.
This Viewpoint discusses the US Food and Drug Administration’s approval of Epidiolex, the first cannabis-derived treatment, for 2 epilepsy syndromes and discusses wider implications.
This Viewpoint suggests approaches to cultural barriers in understanding epilepsy and seizures in Hispanic communities.
This study investigates the utility of reinterpreting the genomic test results of pediatric patients who previously underwent genomic epilepsy testing.
This population-based cohort study of children in Denmark evaluates whether maternal use of valproate or other antiepileptic drugs during pregnancy is associated with the risk of attention-deficit/hyperactivity disorder (ADHD) in offspring.
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