Explore the latest in esophageal cancer, including advances in understanding the epidemiology, diagnosis, management, and prevention of the disease.
This cohort study assesses the clinical utility of circulating tumor DNA as a prognostic biomarker for esophageal squamous cell carcinoma recurrence and survival.
This nonrandomized controlled trial evaluates the safety and antitumor activity of anti-TIGIT antibody tiragolumab and its combination with atezolizumab in patients with advanced solid tumors.
This nonrandomized controlled trial investigates whether the addition of pembrolizumab to perioperative chemotherapy in patients with locally advanced, resectable gastric and gastroesophageal junction adenocarcinoma increases pathologic complete response and whether the addition of maintenance pembrolizumab improves disease-free survival.
This meta-analysis investigates the efficacy and safety of nivolumab plus ipilimumab vs nivolumab alone in the treatment of advanced cancers other than melanoma.
This cross-sectional study examines temporal trends in incidence rates of esophageal cancer, adenocarcinoma of the esophagus, and squamous cell carcinoma of the esophagus from 1975 through 2018.
This meta-analysis evaluates whether proton therapy is associated with better efficacy and safety outcomes, including dosimetry, prognosis, and toxic effects, compared with photon therapy in patients with esophageal cancer.
This randomized clinical trial compares the efficacy and safety of simultaneous integrated boost radiotherapy with concurrent and consolidated oral S-1 chemotherapy vs radiotherapy alone for patients aged 70 years and older with inoperable esophageal squamous cell carcinoma.
This secondary analysis examines the local-regional failure, distant failure, disease-free survival, and overall survival in patients with esophageal cancer who underwent definitive chemoradiotherapy during NRG Oncology randomized clinical trials.
This cohort study investigates demographic, clinical, and therapeutic factors associated with the risk of malignant neoplasms of the gastrointestinal tract after blood or marrow transplant.
This cohort study examines the association of esophagogastric cancer with bariatric surgery in a large national cohort.
This meta-analysis examines whether immunotherapy confers a survival benefit for patients with advanced esophageal squamous cell carcinoma and low expression of PD-L1.
This diagnostic study establishes and validates esophageal squamous cell cancer prediction models for the follow-up stage of esophageal cancer screening and optimization of the esophageal cancer screening program.
This cohort study explores the expression pattern and association of sialic acid–binding immunoglobulin-like lectin 15 (Siglec-15) with outcomes among patients with esophageal squamous cell carcinoma (ESCC) who received neoadjuvant chemoradiotherapy.
This cohort study examines the incidence of esophageal squamous cell carcinoma (ESCC) and the use of surveillance endoscopy in patients with low-grade intraepithelial neoplasia in China.
This prognostic study evaluates the outcomes of concurrent chemoradiotherapy and constructs decision tree models for predicting the risk of progression and mortality in patients with synchronous oligometastatic esophageal squamous cell carcinoma (ESCC).
This validation study evaluates whether diffuse reflectance spectroscopy on gastric and esophageal cancer specimens can differentiate tissue types and provide real-time feedback to the operator.
Customize your JAMA Network experience by selecting one or more topics from the list below.