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    Fungal Infections

    Explore the latest in fungal infections, including recent advances in diagnosis and treatment of cutaneous and systemic infection.

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    • Rapid Point-of-Care Identification of Aspergillus Species in Microbial Keratitis
      JAMA Ophthalmology
      Research
      September 28, 2023

      This diagnostic study examines the diagnostic performance of a lateral-flow assay in detecting Aspergillus species in patients presenting with bacterial or fungal infection.

      Infectious Diseases Pathology and Laboratory Medicine Cornea Ophthalmology
      Full Text | pdf link PDF
    • Endogenous Aspergillus thermomutatus Endophthalmitis in a Patient With Myelodysplastic Syndrome
      JAMA Ophthalmology
      Case Report
      July 20, 2023

      This case report describes a diagnosis of Aspergillus thermomutatus endophthalmitis in a patient with a recent history of allogeneic stem cell transplant.

      Ophthalmology Ophthalmic Images Infectious Diseases Stem Cell Transplantation
      Full Text | pdf link PDF | CME & MOC is active quiz
    • Patients With COVID-19 and Fungal Infections Had High Mortality Rates
      JAMA
      News
      July 18, 2023
      Critical Care Medicine Infectious Diseases Coronavirus (COVID-19)
      Full Text | pdf link PDF
    • Prophylaxis Against Pneumocystis jirovecii Pneumonia in Adults
      JAMA
      Review
      July 11, 2023

      This JAMA Insights Clinical Update discusses current recommendations regarding prevention of Pneumocystis pneumonia in patients who are immunocompromised.

      HIV Infectious Diseases Oncology Transplantation Hematologic Cancer
      Full Text | pdf link PDF | CME & MOC is active quiz
    • Trichophyton mentagrophytes Internal Transcribed Spacer Genotype VIII
      JAMA Dermatology
      Case Report
      July 7, 2023

      This case report describes large, annular, scaly, and erythematous plaques in the axillae and legs extending from the groin as well as involvement of the chest surrounding the areola.

      Dermatology Emergency Medicine Global Health Images in Dermatology Infectious Diseases
      Full Text | pdf link PDF | CME & MOC is active quiz
    • CDC: Candida auris Fungal Infections and Drug Resistance on the Rise
      JAMA
      News
      April 18, 2023
      Critical Care Medicine Infectious Diseases Infection Control
      Full Text | pdf link PDF free
    • An Outbreak of Fungal Endophthalmitis After Cataract Surgery in South Korea
      JAMA Ophthalmology
      Research
      March 1, 2023

      This case series study investigated the clinical features and prognoses associated with fungal endophthalmitis resulting from contaminated medical products.

      Infectious Diseases Health Care Safety Infection Control Ophthalmology Cataract and Other Lens Disorders
      Full Text | pdf link PDF
    • Pigmented Corneal Lesions After Cataract Surgery
      JAMA Ophthalmology
      Case Report
      March 1, 2023

      An 81-year-old woman was referred for darkly pigmented corneal lesions affecting the corneal endothelium and stroma after uncomplicated right cataract surgery 2 years earlier. She was being treated with maintenance loteprednol, 0.5%, eye drops for persistent low-grade anterior uveitis. What would you do next?

      Cornea Infectious Diseases Ophthalmology Clinical Challenge Cataract and Other Lens Disorders
      Full Text | pdf link PDF | CME & MOC is active quiz
    • Expansile Sphenoid Mycetoma Presenting With Headache and Galactorrhea
      JAMA Otolaryngology–Head & Neck Surgery
      Case Report
      February 1, 2023

      This case report describes an immunocompetent woman in her 30s with daily vertex headaches over 13 months duration who developed spontaneous galactorrhea and was diagnosed with noninvasive fungal sinusitis.

      Headache Neurology Obstetrics and Gynecology Infectious Diseases Otolaryngology
      Full Text | pdf link PDF
    • On the Rise, Candida auris Outwits Treatments and Travels Incognito in Health Care Settings
      JAMA
      News
      January 17, 2023

      This Medical News feature examines the relatively newly identified fungus Candida auris, a hardy species that can resist treatment with antifungal agents, is highly contagious, and is associated with serious infections and significant mortality.

      Critical Care Medicine Infectious Diseases Infection Control
      Full Text | pdf link PDF
    • Tinea Nigra Palmaris
      JAMA Dermatology
      Case Report
      December 1, 2022

      This case report describes multiple coalescing brownish black macules with irregular borders over the left palm and palmar aspect of the digits, with black pigmentary accentuation over the creases.

      Global Health Infectious Diseases Images in Dermatology Dermatology Skin Infections
      Full Text | pdf link PDF | CME & MOC is active quiz
    • Difficult Dermatophytosis
      JAMA Dermatology
      Opinion
      November 1, 2022
      Infectious Diseases Skin Infections Dermatology
      Full Text | pdf link PDF
    • Effect of Different Itraconazole Dosing Regimens on Cure Rates, Treatment Duration, Safety, and Relapse Rates in Adult Patients With Tinea Corporis/Cruris: A Randomized Clinical Trial
      JAMA Dermatology
      Research
      November 1, 2022

      This randomized clinical trial compares cure rates, treatment durations, safety profiles, and relapse rates of itraconazole, 100, 200, and 400 mg/d, for the treatment of tinea corporis/cruris in adult patients.

      Infectious Diseases Skin Infections Dermatology
      Full Text | pdf link PDF free
    • Botulinum Toxin A for the Treatment of Yellow Nail Syndrome and Palmar Primary Hyperhidrosis
      JAMA Dermatology
      Case Report
      October 1, 2022

      This case report describes a 23-year-old man with excessive sweating of the bilateral palms and 20 yellow nails.

      Dermatology Nail Disorders Infectious Diseases
      Full Text | pdf link PDF
    • An 18-Year-Old Woman With Recurrent Skin, Nail, and Oral Mucosal Abnormalities
      JAMA
      Case Report
      September 20, 2022

      An 18-year-old woman had a 14-year history of recurrent skin, nail, and oral mucosal abnormalities, treated with 3- to 6-month courses of itraconazole; the abnormalities typically recurred within 6 to 12 months of discontinuing itraconazole. Skin scrapings from the lower extremities demonstrated fungal elements; fungal culture of the skin scrapings grew Candida albicans. What is the diagnosis and what would you do next?

      Allergy and Clinical Immunology Dermatology Nail Disorders Otolaryngology Clinical Challenge
      Full Text | pdf link PDF | CME & MOC is active quiz
    • Cutaneous Blastomycosis
      JAMA Dermatology
      Case Report
      September 1, 2022

      This case report describes a verrucous oval plaque with central atrophy on the right thigh.

      Infectious Diseases Images in Dermatology Dermatology Skin Infections
      Full Text | pdf link PDF
    • Exophytic Laryngeal Mass
      JAMA Otolaryngology–Head & Neck Surgery
      Case Report
      September 1, 2022

      A 29-year-old woman presented with postnasal drip, pharyngitis, odynophagia, cervicalgia, cervical lymphadenopathy, and right-sided otalgia that had persisted for more than a week; what is your diagnosis?

      Infectious Diseases Laryngology Clinical Challenge Otolaryngology Swallowing and Dysphagia
      Full Text | pdf link PDF | CME & MOC is active quiz
    • Progressive Hoarseness and Laryngeal Obstruction in an Elderly Man
      JAMA Otolaryngology–Head & Neck Surgery
      Case Report
      September 1, 2022

      An otherwise healthy man in his 60s with no prior history of smoking, head and neck surgeries, or radiation exposure presented with a 1-year medical history of progressively worsening hoarseness and dyspnea. What is your diagnosis?

      Infectious Diseases Laryngology Otolaryngology Clinical Challenge Critical Care Medicine
      Full Text | pdf link PDF | CME & MOC is active quiz
    • Tinea Pseudoimbricata
      JAMA Dermatology
      Case Report
      May 1, 2022

      This case report describes multiple erythematous to hyperpigmented plaques comprising concentric rings with associated scale on the upper back.

      Infectious Diseases Images in Dermatology Dermatology Skin Infections
      Full Text | pdf link PDF | CME & MOC is active quiz
    • Decreased Vision and Eye Pain in a 55-Year-Old Man
      JAMA Ophthalmology
      Case Report
      March 1, 2022

      A 55-year-old man with advanced primary open-angle glaucoma presented with 1 day of decreased vision and eye pain. He had undergone trabeculectomy and 5-fluorouracil injection 1 month prior. What would you do next?

      Infectious Diseases Ophthalmology Clinical Challenge Glaucoma
      Full Text | pdf link PDF | CME & MOC is active quiz
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