Explore the latest in fungal infections, including recent advances in diagnosis and treatment of cutaneous and systemic infection.
This systematic review and network meta-analsysis compares antifungal prophylaxis drugs for patients with hematological disease or who are undergoing hematopoietic stem cell transplantation (HSCT).
An older adult presents with a solitary, well-circumscribed pink plaque with overlying yellow-white micaceous scale on the elbow at the site of a prior injury. What is your diagnosis?
This population-based cohort study examines associations of voriconazole and other antifungal medications with risk of keratinocyte carcinomas in recipients of lung transplants.
A woman from the Southeastern US with a history of smoking, poorly controlled diabetes, and inhalational medical marijuana use had 4 months of productive cough, weight loss, subjective fevers, 3 days of worsening chest pain, and a large right upper lobe cavitary mass on chest CT unresponsive to antibiotics. AFB smear and GeneXpert MTB/RIF testing were negative; she developed a right-sided tension pneumothorax after intubation for hypoxemia, and chest tube placement yielded charcoal-colored pleural fluid. What is the diagnosis and what would you do next?
This cohort study examines the association between use of oral or topical terbinafine and malformations and spontaneous abortions in women who receive terbinafine during pregnancy.
This cross-sectional study investigates which features of a typical postfungal keratitis corneal scar are most associated with vision loss and evaluates the use of corneal imaging metrics as cornea-specific outcomes for clinical studies.
This case report describes a man in his 50s with diabetes mellitus who presented with 2 months of right-sided aural fullness and tinnitus without fever or pain and was subsequently diagnosed with Blastomyces dermatitidis–associated skull base osteomyelitis.
This randomized trial compares the effect of prophylactic caspofungin vs fluconazole on invasive fungal disease among patients between the ages of 3 months to 30 years with acute myeloid leukemia.
This JAMA Insights Clinical Update reviews infection control and treatment strategies to manage Candida auris, a new drug-resistant fungal species that can cause severe invasive infection with high morbidity and mortality in patients with underlying comorbid illnesses.
This JAMA Patient Page describes causes, control, and prevention of infection with the yeast Candida auris.
This case report describes a woman in her 40s who became infected with Talaromyces marneffei and other pathogens after developing an adult-onset immunodeficiency syndrome.
A man with a perforation of the hard palate was admitted following 3 weeks of dysphagia; 1 week of nasal regurgitation, nonproductive cough, and breathy voice; a 25-pound weight loss over the preceding 2 months; and a 1-year history of HIV infection and hepatic tuberculosis. What is your diagnosis?
A woman in her 50s with refractory acute myeloid leukemia and a history of breast cancer presented with new pulmonary nodules, elevated serum β-D-glucan levels, and subsequent pink papules on trunk and extremities. What is your diagnosis?
This systematic review determines guideline efficacy by reconciling discrepancies in the incidence of endophthalmitis and evaluating outcomes of studies assessing ophthalmologic screening for candidemia.
This study assesses the rate and utility of monitoring laboratory test result abnormalities in adults and children taking terbinafine and griseofulvin for treatment of dermatophyte infections.
This case report describes a pregnant woman who developed tinea manus from Trichophyton erinacei infection transmitted to her from her pet hedgehogs.
This pharmacoepidemiology study uses Swedish and Norwegian registry data to investigate associations between fluconazole use during pregnancy and subsequent stillbirth and neonatal death.
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